Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention

European Journal of Cancer and Clinical Oncology - Tập 17 Số 11 - Trang 1155-1163 - 1981
N Brock1, J. Pohl1, Jurij Stekar1
1Asta-Werke AG Degussa Pharma-Gruppe, Abteilung Experimentelle Tumorforschung, D-4800 Bielefeld 14, Federal Republic of Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Brock, 1981, Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention. 1. Experimental studies on the urotoxicity of alkylating compounds, Eur J Cancer, 17, 595, 10.1016/0014-2964(81)90261-9

Brock, 1979, Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide, Arzneim-Forsch (Drug Res), 29, 659

Brock, 1980, The development of mesna for the inhibition of urotoxic side effects of cyclophosphamide, ifosfamide and other osazaphosphorine cytostatics, Recent Results Cancer Res, 74, 270, 10.1007/978-3-642-81488-4_32

Vahlensiek, 1974, Zur Pathogenese, Klinik und Prophylaxe der sogenannten Cyclophosphamid-Zystitis, Munch Med Wochenschr, 116, 1889

Levy, 1977, Effect of N-acetylcysteine on some aspects of cyclophosphamide-induced toxicity and immunosuppression, Biochem Pharmacol, 26, 1015, 10.1016/0006-2952(77)90237-4

Tolley, 1975, Cyclophosphamide-induced cystitis of the urinary bladder of rats and its treatment, 68, 169

Primack, 1971, Amelioration of cyclophosphamide-induced cystitis, J Natl Cancer Inst, 47, 223

Brock, 1977, The problem of specificity and selectivity of alkylating cytostatics: studies on N-2-chloroethylamido-oxazaphosphorines, Z Krebsforsch, 88, 185, 10.1007/BF00284124

Hohorst, 1976, The problem of oncostatic specificity of cyclophosphamide (NSC-26271): studies on reactions that control the alkylating and cytotoxic activity, Cancer Treat Rep, 60, 309

Kline, 1973, Protection with N-Acetyl-l-cysteine (NSC-111180) against isophosphamide (NSC-109724) toxicity and enhancement of therapeutic effect in early murine L1210 leukemia, Cancer Chemother Rep, 57, 299

Goldin, 1977, Preclinical investigations with ifosfamide in relation to cyclophosphamide, 19

Connors, 1966, Protection against the toxicity of alkylating agents by thiols: the mechanism of protection and its relevance to cancer chemotherapy, Eur J Cancer, 2, 293, 10.1016/0014-2964(66)90042-9

Ishidate, 1953, Studies on the toxicity of “Nitromin”. Interference of cysteine upon “Nitromin” toxicity, Gann, 44, 386

Brock, 1979, Antidot gegen urotoxische Wirkangen der Oxazaphosphorin-Derivate Cyclophosphamid, Ifosfamid und Trofosfamid, Naturwissenschaften, 66, 60, 10.1007/BF00369371

Kelly, 1960, Actions of S,2-aminoethylisothiuronium Br. HBr (AET). Toxicity and protective effect against nitrogen mustard toxicity, J Pharmacol Exp Ther, 129, 218

Habs, 1981, Influence of pretreatment with disulfiram (DSF) on the acute toxicity of cyclophosphamide (CP) in male Sprague-Dawley rats, ArzneimForsch (Drug Res), 31, 530

Ellman, 1959, Tissue sulfhydryl groups, Arch Biochem Biophys, 82, 70, 10.1016/0003-9861(59)90090-6

Stekar J. In preparation (1981).

Brock, 1981, Arzneim-Forsch (Drug Res)

van Dyk, 1972, Unexpected toxicity in patients treated with iphosphamide, Cancer Res, 32, 921

Stekar J, Brock J. In preparation.

Pohl, 1980, Toxikologie, Pharmakokinetik und Interaktionen von Uromitexan, Bd. 5, 12