Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention—I

European Journal of Cancer (1965) - Tập 17 Số 6 - Trang 595-607 - 1981
N Brock1, J. Pohl1, Jurij Stekar1
1Asta-Werke, A.G. Degǔssa Pharma-Gruppe, Abteilung Experimentelle Tumorforschung, Postfach 1401 29, 4800 Bielefeld 14, Federal Republic of Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Brock, 1979, The special position of ifosfamide in the series of cytostatically active oxazaphosphorines, 39

Goldin, 1977, 19

Arnold, 1958, Neuartige Krebs-Chemotherapeutika aus der Gruppe der zyklischen N-Lost-Phosphamidester, Naturwissenschaften, 45, 64, 10.1007/BF00638623

Brock, 1973, Pharmakologische Untersuchungen mit Trofosfamid (Ixoten®), einem neuen Oxazaphosphorinoxid, Med. Monatsschr., 27, 300

Brock, 1972, Pharmacological studies with ifosfamide — a new oxazaphosphorine compound, 759

Joss, 1980, Komplikationen im Bereich der Niere und der ableitenden Harnwege im Verlauf von Tumorkrankheiten, Schweiz Med Wochenschr, 110, 390

Hill, 1975

Anderson, 1967, Cyclophosphamide hemorrhagic cystitis, J Urol, 97, 857, 10.1016/S0022-5347(17)63134-3

van Dyk, 1972, Unexpected toxicity in patients treated with iphosphamide, Cancer Res, 32, 921

Philips, 1961, Cyclophosphamide and urinary bladder toxicity, Cancer Res, 21, 1577

Vahlensiek, 1974, Zur Pathogenese, Klinik und Prophylaxe der sogenannten Cyclophosphamid-Zystitis, Münch Med Wochenschr, 116, 1889

Levy, 1977, Effect of N-acetylcysteine on some aspects of cyclophosphamide-induced toxicity and immunosuppression, Biochem Pharmacol, 26, 1015, 10.1016/0006-2952(77)90237-4

Tolley, 1975, Cyclophosphamide-induced cystitis of the urinary bladder of rats and its treatment, 68, 169

Connors, 1966, Protection against the toxicity of alkylating agents by thiols: the mechanism of protection and its relevance to cancer chemotherapy, Eur J Cancer, 2, 293, 10.1016/0014-2964(66)90042-9

Ishidate, 1953, Studies on the toxicity of “Nitromin”, Gann, 44, 386

Friedman, 1961, Colorimetric estimation of nitrogen mustards in aqueous media, Anal Chem, 33, 906, 10.1021/ac60175a029

Koss, 1967, A light and electron microscopic study of the effects of a single dose of cyclophosphamide on various organs in the rat. I. The urinary bladder, Lab Invest, 16, 44

Koss, 1970, Effects of a single dose of cyclophosphamide on various organs in the rat. II. Response of urinary bladder epithelium according to strain and sex, J Natl Cancer Inst, 44, 1195

Kunze, 1980, Proliferationskinetik regenerierender Urothelzellen in der Rattenharnblase nach Applikation von Cyclophosphamid, Virchows Arch (Cell Path, 33, 47, 10.1007/BF02899170

Brock, 1971, Activation of cyclophosphamide in man and animals, Cancer, 27, 1512, 10.1002/1097-0142(197106)27:6<1512::AID-CNCR2820270636>3.0.CO;2-Q

Brock, 1963, Uber die Aktivierung von Cyclophosphamid in vivo und in vitro, Arzneim Forsch, 13, 1021

Wagner, 1980, Über Blutspiegel und Urin-Ausscheidung von aktiviertem Cyclophosphamid und seinen Deaktivierungsprodukten beim Menschen, J Cancer Res Clin Oncol, 96, 79, 10.1007/BF00412899

Brock N, Pohl J, Schneider B, Stekar J. Publication in preparation.

Stekar J. Unpublished experiments.

Brock, 1979, Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide, Arzneim Forsch, 29, 659

Cox, 1976, The use of cyclophosphamide analogs in mechanistic studies of the metabolism of cyclophosphamide, Vol. 1, 59