Structure and Function of the Epidermal Growth Factor (EGF⧸ErbB) Family of Receptors
Tài liệu tham khảo
Agus, 2002, Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth, Cancer Cell, 2, 127, 10.1016/S1535-6108(02)00097-1
Arteaga, 2002, Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia, Semin. Oncol, 29, 3, 10.1053/sonc.2002.35642
Arteaga, 2003, ErbB-targeted therapeutic approaches in human cancer, Exp. Cell Res, 284, 122, 10.1016/S0014-4827(02)00104-0
Bajaj, 1987, On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors, Biochim. Biophys. Acta, 916, 220, 10.1016/0167-4838(87)90112-9
Bargmann, 1986, Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185, Cell, 45, 649, 10.1016/0092-8674(86)90779-8
Bargmann, 1986, The neu oncogene encodes an epidermal growth factor receptor-related protein, Nature, 319, 226, 10.1038/319226a0
Bargmann, 1988, Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene, Proc. Natl. Acad. Sci. USA, 85, 5394, 10.1073/pnas.85.15.5394
Bargmann, 1988, Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion, EMBO J, 7, 2043, 10.1002/j.1460-2075.1988.tb03044.x
Baselga, 2001, Mechanism of action of trastuzumab and scientific update, Semin. Oncol, 28, 4, 10.1016/S0093-7754(01)90276-3
Blume-Jensen, 2001, Oncogenic kinase signalling, Nature, 411, 355, 10.1038/35077225
Brennan, 2000, HER2⧸neu: Mechanisms of dimerization⧸oligomerization, Oncogene, 19, 6093, 10.1038/sj.onc.1203967
Brown, 1994, The extracellular domain of the epidermal growth factor receptor. Studies on the affinity and stoichiometry of binding, receptor dimerization and a binding-domain mutant, Eur. J. Biochem, 225, 223, 10.1111/j.1432-1033.1994.00223.x
Burgess, 2003, An open-and-shut case? Recent insights into the activation of EGF⧸ErbB receptors, Mol. Cell, 12, 541, 10.1016/S1097-2765(03)00350-2
Burke, 1997, Dimerization of the p185neu transmembrane domain is necessary but not sufficient for transformation, Oncogene, 14, 687, 10.1038/sj.onc.1200873
Carpenter, 1987, Receptors for epidermal growth factor and other polypeptide mitogens, Annu. Rev. Biochem, 56, 881, 10.1146/annurev.bi.56.070187.004313
Carpenter, 2003, ErbB-4: Mechanism of action and biology, Exp. Cell Res, 284, 66, 10.1016/S0014-4827(02)00100-3
Carpenter, 1979, Epidermal growth factor, Annu. Rev. Biochem, 48, 193, 10.1146/annurev.bi.48.070179.001205
Carpenter, 1978, Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro, Nature, 276, 409, 10.1038/276409a0
Carpenter, 1979, Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor, J. Biol. Chem, 254, 4884, 10.1016/S0021-9258(17)30094-7
Carpenter, 1975, Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts, J. Biol. Chem, 250, 4297, 10.1016/S0021-9258(19)41417-8
Cho, 2002, Structure of the extracellular region of HER3 reveals an interdomain tether, Science, 297, 1330, 10.1126/science.1074611
Cho, 2003, Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab, Nature, 421, 756, 10.1038/nature01392
Citri, 2003, The deaf and the dumb: The biology of ErbB-2 and ErbB-3, Exp. Cell Res, 284, 54, 10.1016/S0014-4827(02)00101-5
Clynes, 2000, Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets, Nat. Med, 6, 443, 10.1038/74704
Cohen, 1986, Nobel lecture. Epidermal growth factor, Biosci. Rep, 6, 1017, 10.1007/BF01141022
Cohen, 1987, Epidermal growth factor, In Vitro Cell Dev. Biol, 23, 239, 10.1007/BF02623704
Cohen, 1980, Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity, J. Biol. Chem, 255, 4834, 10.1016/S0021-9258(19)85573-4
Cohen, 1982, A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles, J. Biol. Chem, 257, 1523, 10.1016/S0021-9258(19)68224-4
Das, 1977, Specific radiolabeling of a cell surface receptor for epidermal growth factor, Proc. Natl. Acad. Sci. USA, 74, 2790, 10.1073/pnas.74.7.2790
de Vos, 1992, Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex, Science, 255, 306, 10.1126/science.1549776
Di Fiore, 1987, erbB-2 is a potent oncogene when overexpressed in NIH⧸3T3 cells, Science, 237, 178, 10.1126/science.2885917
Downward, 1984, Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences, Nature, 307, 521, 10.1038/307521a0
Elleman, 2001, Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain, Biochemistry, 40, 8930, 10.1021/bi010037b
Ferguson, 2003, EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization, Mol. Cell, 11, 507, 10.1016/S1097-2765(03)00047-9
Franklin, 2004, Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex, Cancer Cell, 5, 317, 10.1016/S1535-6108(04)00083-2
Frykberg, 1983, Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes, Cell, 32, 227, 10.1016/0092-8674(83)90513-5
Gadella, 1995, Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation, J. Cell Biol, 129, 1543, 10.1083/jcb.129.6.1543
Garrett, 2003, The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors, Mol. Cell, 11, 495, 10.1016/S1097-2765(03)00048-0
Garrett, 2002, Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha, Cell, 110, 763, 10.1016/S0092-8674(02)00940-6
Garrett, 1998, Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor, Nature, 394, 395, 10.1038/28668
Gassmann, 1995, Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor, Nature, 378, 390, 10.1038/378390a0
Gerstner, 2002, Sequence plasticity in the antigen-binding site of a therapeutic anti-HER2 antibody, J. Mol. Biol, 321, 851, 10.1016/S0022-2836(02)00677-0
Grasberger, 1986, Interaction between proteins localized in membranes, Proc. Natl. Acad. Sci. USA, 83, 6258, 10.1073/pnas.83.17.6258
Guy, 1994, Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity, Proc. Natl. Acad. Sci. USA, 91, 8132, 10.1073/pnas.91.17.8132
Haigler, 1979, Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431, J. Cell. Biol, 81, 382, 10.1083/jcb.81.2.382
Heldin, 1995, Dimerization of cell surface receptors in signal transduction, Cell, 80, 213, 10.1016/0092-8674(95)90404-2
Hock, 1979, Isolation of the human placenta receptor for epidermal growth factor-urogastrone, Nature, 277, 403, 10.1038/277403a0
Holbro, 2003, The ErbB receptors and their role in cancer progression, Exp. Cell Res, 284, 99, 10.1016/S0014-4827(02)00099-X
Humphrey, 1991, Deletion-mutant epidermal growth factor receptor in human gliomas: Effects of type II mutation on receptor function, Biochem. Biophys. Res. Commun, 178, 1413, 10.1016/0006-291X(91)91051-D
Humphrey, 1990, Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma, Proc. Natl. Acad. Sci. USA, 87, 4207, 10.1073/pnas.87.11.4207
Jiang, 1999, Receptor signaling: When dimerization is not enough, Curr. Biol, 9, R568, 10.1016/S0960-9822(99)80357-1
Kelley, 1993, Thermodynamic analysis of an antibody functional epitope, Biochemistry, 32, 6828, 10.1021/bi00078a005
Klapper, 1999, The ErbB-2⧸HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors, Proc. Natl. Acad. Sci. USA, 96, 4995, 10.1073/pnas.96.9.4995
Klapper, 2000, Biochemical and clinical implications of the ErbB⧸HER signaling network of growth factor receptors, Adv. Cancer Res, 77, 25, 10.1016/S0065-230X(08)60784-8
Kohda, 1993, A 40-kDa epidermal growth factor⧸transforming growth factor alpha-binding domain produced by limited proteolysis of the extracellular domain of the epidermal growth factor receptor, J. Biol. Chem, 268, 1976, 10.1016/S0021-9258(18)53950-8
Kraulis, 1991, A program to produce both detailed and schematic plots of protein structures, Journal of Applied Crystallography, 24, 946, 10.1107/S0021889891004399
Lax, 1989, Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken⧸human receptor molecules, EMBO J, 8, 421, 10.1002/j.1460-2075.1989.tb03393.x
Lax, 1988, Chicken epidermal growth factor (EGF) receptor: cDNA cloning, expression in mouse cells, and differential binding of EGF and transforming growth factor alpha, Mol. Cell. Biol, 8, 1970, 10.1128/MCB.8.5.1970
Lee, 1995, Requirement for neuregulin receptor erbB2 in neural and cardiac development, Nature, 378, 394, 10.1038/378394a0
Lemmon, 1997, Two EGF molecules contribute additively to stabilization of the EGFR dimer, EMBO J, 16, 281, 10.1093/emboj/16.2.281
Mattoon, 2004, The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function, Proc. Natl. Acad. Sci. USA, 101, 923, 10.1073/pnas.0307286101
Miettinen, 1995, Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor, Nature, 376, 337, 10.1038/376337a0
Molina, 2001, Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells, Cancer Res, 61, 4744
Molina, 2002, NH(2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer, Clin. Cancer Res, 8, 347
Moriki, 2001, Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain, J. Mol. Biol, 311, 1011, 10.1006/jmbi.2001.4923
Morris, 1999, Rescue of the cardiac defect in ErbB2 mutant mice reveals essential roles of ErbB2 in peripheral nervous system development, Neuron, 23, 273, 10.1016/S0896-6273(00)80779-5
Muller, 1996, Characterization of the receptor protein-tyrosine kinase gene from the marine sponge Geodia cydonium, Prog. Mol. Subcell Biol, 17, 183, 10.1007/978-3-642-80106-8_9
Ogiso, 2002, Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains, Cell, 110, 775, 10.1016/S0092-8674(02)00963-7
Olayioye, 2000, The ErbB signaling network: Receptor heterodimerization in development and cancer, EMBO J, 19, 3159, 10.1093/emboj/19.13.3159
Riethmacher, 1997, Severe neuropathies in mice with targeted mutations in the ErbB3 receptor, Nature, 389, 725, 10.1038/39593
Sako, 2000, Single-molecule imaging of EGFR signalling on the surface of living cells, Nat. Cell Biol, 2, 168, 10.1038/35004044
Schechter, 1979, Local aggregation of hormone-receptor complexes is required for activation by epidermal growth factor, Nature, 278, 835, 10.1038/278835a0
Schlessinger, 2000, Cell signaling by receptor tyrosine kinases, Cell, 103, 211, 10.1016/S0092-8674(00)00114-8
Schlessinger, 2003, Signal transduction. Autoinhibition control, Science, 300, 750, 10.1126/science.1082024
Sibilia, 1995, Strain-dependent epithelial defects in mice lacking the EGF receptor, Science, 269, 234, 10.1126/science.7618085
Sizeland, 1992, Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line, Mol. Biol. Cell, 3, 1235, 10.1091/mbc.3.11.1235
Slamon, 2001, Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2, N. Engl. J. Med, 344, 783, 10.1056/NEJM200103153441101
Slamon, 1987, Human breast cancer: Correlation of relapse and survival with amplification of the HER-2⧸neu oncogene, Science, 235, 177, 10.1126/science.3798106
Sliwkowski, 1999, Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin), Semin. Oncol, 26, 60
Stamos, 2002, Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor, J. Biol. Chem, 277, 46265, 10.1074/jbc.M207135200
Stein, 2000, Evolutionary analysis of the ErbB receptor and ligand families, J. Mol. Evol, 50, 397, 10.1007/s002390010043
Tang, 1998, EGF family of receptors and their ligands in human cancer, 113
Threadgill, 1995, Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype, Science, 269, 230, 10.1126/science.7618084
Todaro, 1976, Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells, Nature, 264, 26, 10.1038/264026a0
Ullrich, 1984, Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells, Nature, 309, 418, 10.1038/309418a0
Ushiro, 1980, Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes, J. Biol. Chem, 255, 8363, 10.1016/S0021-9258(18)43497-7
Ward, 1995, Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor, Proteins, 22, 141, 10.1002/prot.340220207
Wrann, 1979, Identification of the EGF receptor on 3T3 cells by surface-specific iodination and gel electrophoresis, FEBS Lett, 104, 415, 10.1016/0014-5793(79)80865-0
Yamamoto, 1986, Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor, Nature, 319, 230, 10.1038/319230a0
Yamamoto, 1983, The erbB gene of avian erythroblastosis virus is a member of the src gene family, Cell, 35, 71, 10.1016/0092-8674(83)90209-X
Yarden, 1987, Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor, Biochemistry, 26, 1443, 10.1021/bi00379a035
Yarden, 2001, Untangling the ErbB signalling network, Nat. Rev. Mol. Cell. Biol, 2, 127, 10.1038/35052073