Stereotactic radiosurgery in the management of cancer pain
Tóm tắt
Pain can be a significant problem for the patient with advanced cancer, particularly if bone metastases are present. Radiation therapy is efficacious and has been a mainstay in the treatment of pain from bone metastases. In the past decade, radiosurgery has developed into a successful adjunct treatment for these patients. The indications for radiosurgery are continually expanding, and new and more sophisticated equipment is being developed to deliver more precise treatments. This article discusses the biology, rationale, evolution, and future direction of radiosurgery for the treatment of pain related to bony metastatic disease.
Tài liệu tham khảo
Healthcommunications.com: Cancer pain: overview, incidence, and prevalence. Available at http://www.oncologychannel.com/pain/index.shtml. Accessed February 2009.
Nielson OS, Munro AJ, Tannock IF: Bone metastases: pathophysiology and management policy. J Clin Oncol 1991, 9:509–519.
Tse V: Metastatic disease to the spine and related structures. Available at http://emedicine.medscape.com/article/1157987-overview. Accessed February 2009.
Hall E, Giaccia A: Radiobiology for the Radiologist, edn 6. Philadelphia: Lippincott Williams & Wilkins; 2006:378–381.
Tong D, Gillick L, Hendrickson F: Palliation of symptomatic osseous metastases. Cancer 1982, 50:893–899.
Blitzer PH: Re-analysis of the RTOG study of the palliation of symptomatic osseous metastases. Cancer 1985, 55:1468–1472.
Hartsell W, Scott C, Bruner D, et al.: Randomization of short-versus long-course radiotherapy for palliation of painful bony metastases. J Natl Cancer Inst 2005, 97:798–804.
Chow E, Harris K, Fan G, et al.: Palliative radiotherapy trials for bone metastases: a systematic review. J Clin Oncol 2007, 25:1423–1436.
Niranjan A, Gobbel GT, Kondziolka D: Experimental radiobiological investigations into radiosurgery: present understanding and future directions. Neurosurgery 2004, 55:495–507.
Pensak ML: Controversies in Otolaryngology. New York: Thieme Medical Publishing; 2001:271.
Khan F: The Physics of Radiation Therapy, edn 3. Philadelphia: Lippincott Williams & Wilkins; 2003:514–515.
Heilbrun P: Cyberknife Radiosurgery: A Practical Guide. Sunnyvale, CA: CyberKnife Society Press; 2003:vii.
University of Pittsburgh Medical Center: Neurosurgical Oncology Center page. Available at http://www.neurosurgery.pitt.edu/neuro_oncology/synergy.html. Accessed February 2009.
Haley M, Gerszten PC, Burton S: The role of radiosurgery in the treatment of bone localized cancers. In Bone and Cancer, Topics in Bone Biology. Edited by Bronner F, Farach-Carson M. London: Springer-Verlag; 2009:241–251.
Ryken T, Meeks S, Traynelis V, et al.: Ultrasonographic guidance for spinal extracranial radiosurgery: technique and application for metastatic spinal lesions. Neurosurg Focus 2001, 11:1–6.
Medical News Today: CyberKnife spinal tumor treatments increase by 56 percent: success of non-invasive procedure chronicled in the journal Spine. Available at http://www.medicalnewstoday.com/articles/63762.php. Accessed February 2009.
Varian Medical Systems: Oncology/Radiation Oncology: Trilogy overview page. Available at http://www.varian.com/us/oncology/radiation_oncology/trilogy. Accessed February 2009.
Benzil DL, Saboori M, Mogilner AY, et al.: Safety and efficacy of stereotactic radiosurgery for tumors of the spine. J Neurosurg 2004, 101:413–418.
Gagnon GJ, Nasr NM, Liao JJ: Treatment of spinal tumors using cyberknife fractionated stereotactic radiosurgery: pain and quality-of-life assessment after treatment in 200 patients. Neurosurgery 2009, 64:297–306.
Yamada Y, Lovelock M, Yenice KM, et al.: Multifractionated image-guided and stereotactic intensity modulated radiotherapy of paraspinal tumors: a preliminary report. Int J Radiat Oncol Biol Phys 2005, 62:53–61.
Gerszten P, Burton S, Ozhasoglu C, et al.: Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution. Spine 2007, 32:193–199.
Gerszten PC: Whole body and spinal radiosurgery. In Textbook of Stereotactic and Functional Neurosurgery. Edited by Lozano AM, Gildenberg PL, Tasker RR. Berlin/Heidelberg: Springer-Verlag; 2009 (in press).
Emami B, Lyman J, Brown A, et al.: Tolerance of normal tissue to therapeutic radiation. Int J Radiat Oncol Biol Phys 1991, 21:109–122.
Chang E, Shiu A, Mendel E, Mathews L, et al.: Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure. J Neurosurg Spine 2007, 7:151–160.
Chang E, Shiu A, Lii M, et al.: Phase 1 clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic radiotherapy for spinal metastases. Int J Radiat Oncol Biol Phys 2004, 59:1288–1294.