Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

Adams, 1985, The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice, Nature, 318, 533, 10.1038/318533a0

Bargmann, 1986, The neu oncogene encodes an epidermal growth factor receptor-related protein, Nature, 319, 226, 10.1038/319226a0

Bargmann, 1986, Multiple independent activations of the c-neu oncogene by a point mutation altering the trans-membrane domain of p185, Cell, 45, 649, 10.1016/0092-8674(86)90779-8

Bautch, 1987, Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene, Cell, 51, 529, 10.1016/0092-8674(87)90122-X

Bolen, 1984, Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation, Cell, 38, 767, 10.1016/0092-8674(84)90272-1

Brinster, 1984, Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors, Cell, 37, 367, 10.1016/0092-8674(84)90367-2

Cato, 1987, The hormone response element of the mouse mammary tumor virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal region, EMBO J., 6, 363, 10.1002/j.1460-2075.1987.tb04763.x

Chirgwin, 1979, Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry, 18, 5294, 10.1021/bi00591a005

Courtneidge, 1983, Polyoma virus transforming protein associates with the product of the c-src cellular gene, Nature, 303, 435, 10.1038/303435a0

Coussens, 1985, Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene, Science, 230, 1132, 10.1126/science.2999974

Davis, 1980, Rapid DNA isolations for enzymatic and hybridization analysis, Meth. Enzymol., 65, 404, 10.1016/S0076-6879(80)65051-4

DiFiore, 1987, erbB-2 is a potent oncogene when overexpressed in NIH3T3 cells, Science, 237, 178, 10.1126/science.2885917

Escot, 1986, Genetic alteration of the c-myc proto-oncogene (MYC) in human primary breast carcinomas, 83, 4834

Hafen, 1983, An improved in situ hybridization method for detection of cellular RNA in Drosophila tissue sections and its application for localizing transcripts of homeotic antennapedia gene complex, EMBO J., 2, 617, 10.1002/j.1460-2075.1983.tb01472.x

Hanahan, 1986, Heritable-formation of pancreatic beta cell tumors in transgenic mice expressing recombinant insulin/SV40 oncogenes, Nature, 315, 115, 10.1038/315115a0

Huang, 1981, Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus, Cell, 27, 245, 10.1016/0092-8674(81)90408-6

Hudziak, 1987, Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH3T3 cells, 84, 7159

King, 1985, Amplification of a novel v-erbB-related gene in human mammary carcinoma, Science, 229, 974, 10.1126/science.2992089

Kleinberg, 1987, Prolactin and breast cancer, N. Engl. J. Med., 316, 269, 10.1056/NEJM198701293160508

Kokai, 1987, Stage- and tissue-specific expression of the c-neu oncogene in rat development, 84, 8498

Kraus, 1987, Over-expression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms, EMBO J., 6, 605, 10.1002/j.1460-2075.1987.tb04797.x

Leder, 1986, Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development, Cell, 45, 485, 10.1016/0092-8674(86)90280-1

Melton, 1984, Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriphage SP6 promoter, Nucl. Acids Res., 12, 7035, 10.1093/nar/12.18.7035

Mulligan, 1981, Selection for animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyl transferase, 78, 2072

Padhy, 1982, Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastoma, Cell, 28, 865, 10.1016/0092-8674(82)90065-4

Palmiter, 1986, Germline transformation of mice, Annu. Rev. Genetics, 20, 465, 10.1146/annurev.ge.20.120186.002341

Pattengale, 1983, Experimental models of lymphoproliferative disease: the mouse as a model for human non-Hodgkins lymphomas related leukemias, Am. J. Pathol., 113, 237

Quiafe, 1987, Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice, Cell, 48, 1023, 10.1016/0092-8674(87)90710-0

Quinn, 1982, Preservation of hamster oocytes to assay the fertilizing capacity of human spermatozoa, J. Reprod. Fert., 66, 161, 10.1530/jrf.0.0660161

Rigby, 1977, Labeling deoxyribonucleic acid to high, specific activity in vitro by nick-translation with DNA polymerase 1, J. Mol. Biol., 113, 237, 10.1016/0022-2836(77)90052-3

Ruther, 1987, Deregulated c-fos expression interferes with normal bone development in transgenic mice, Nature, 325, 412, 10.1038/325412a0

Schechter, 1984, The c-neu oncogene: an erbB-related gene encoding a 185,0000-Mw tumour antigen, Nature, 312, 513, 10.1038/312513a0

Schechter, 1985, The c-neu gene: an erbB-homologous gene distinct from and unlinked to genes encoding the EGF receptor, Science, 229, 976, 10.1126/science.2992090

Schoenenberger, 1988, Targeted c-myc expression in mammary glands of transgenic mice induces constitutive milk protein gene transcription, EMBO J., 7, 169, 10.1002/j.1460-2075.1988.tb02797.x

Semba, 1985, A v-erbB related proto-oncogene, c-erbB-2 is distinct from c-erbB-1/epidermal growth factor receptor gene and is amplified in a human salivary gland adenocarcinoma, 82, 6497

Shih, 1981, Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts, Nature, 290, 261, 10.1038/290261a0

Sinn, 1987, Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic actions of oncogenes in vivo, Cell, 49, 465, 10.1016/0092-8674(87)90449-1

Slamon, 1987, Human breast cancer: correlation of relapse and survival with amplification of HER-2/neu oncogene, Science, 235, 177, 10.1126/science.3798106

Southern, 1975, Detection of specific sequences among DNA fragments separated by gel electrophoresis, J. Mol. Biol., 98, 503, 10.1016/S0022-2836(75)80083-0

Stern, 1986, p185, product of the c-neu proto-oncogene is a receptor-like protein associated with tyrosine kinase activity, Mol. Cell. Biol., 6, 1729, 10.1128/MCB.6.5.1729

Stewart, 1984, Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/mvc fusion genes, Cell, 38, 627, 10.1016/0092-8674(84)90257-5

Stewart, 1988, Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice, Mol. Cell. Biol., 8, 473, 10.1128/MCB.8.1.473

Thomas, 1980, Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose, 77, 5201

van de Vijver, 1987, Amplification of the c-neu (c-erbB-2) oncogene in human mammary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene, Mol. Cell. Biol., 7, 2019, 10.1128/MCB.7.5.2019

Williams, 1988, Embryonic lethalities and endothelial tumors in chimeric mice expressing polyoma virus middle T oncogene, Cell, 22, 121

Zarbl, 1985, Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methyl urea during initiation of mammary carcinogenesis in rats, Nature, 315, 382, 10.1038/315382a0

Zeller, 1987, Localized expression of teh atrial natriuretic factor gene during cardiac embryogenesis, Genes & Development, 1, 693, 10.1101/gad.1.7.693

Zeller, 1983, Nucleocytoplasmic distribution of snRNPs and stockpiled snRNA-binding proteins during oogenesis and early development in Xenopus leavis, Cell, 32, 425, 10.1016/0092-8674(83)90462-2