Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Cell Metabolism - Tập 24 Số 4 - Trang 593-607 - 2016
Åsa Segerstolpe1,2, Athanasia Palasantza1, Pernilla Eliasson3, Eva-Marie Andersson3, Anne‐Christine Andréasson3, Xiaoyan Sun4, Simone Picelli5, Alan Sabirsh3, Maryam Clausen6, Magnus Bjursell7, David M. Smith8, Maria Kasper4, Carina Ämmälä3, Rickard Sandberg1,2,5
1Department of Cell and Molecular Biology (CMB), Karolinska Institutet, 171 77, Stockholm, Sweden
2Integrated Cardio Metabolic Center (ICMC), Karolinska Institutet, 141 57 Huddinge, Sweden
3Cardiovascular and Metabolic Diseases (CVMD), Innovative Medicines and Early Development Biotech Unit (iMed), AstraZeneca, 431 83 Mölndal, Sweden
4Department of Biosciences and Nutrition and Center for Innovative Medicine, Novum, Karolinska Institutet, 141 83 Huddinge, Sweden
5Ludwig Institute for Cancer Research, 171 77 Stockholm, Sweden
6Discovery Sciences, Innovative Medicines and Early Development Biotech Unit (iMed), AstraZeneca, 431 83 Mölndal, Sweden
7R&D Information (RDI), AstraZeneca, 431 83 Mölndal, Sweden
8Discovery Sciences, Innovative Medicines and Early Development Biotech Unit (iMed), AstraZeneca, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, UK

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