Silyl modification of biologically active compounds. 3. organosilicon derivatives of aminoalcohols in the series of tetrahydroquinoline, tetrahydroisoquinoline, and tetrahydrosilaisoquinoline

Chemistry of Heterocyclic Compounds - Tập 32 - Trang 682-688 - 1996
É. Lukevits1, I. Segal1, A. Zablotskaya1, S. Germane1
1Latvian Institute of Organic Synthesis, Riga

Tóm tắt

The N-(2′-hydroxyethyl)-1, 2, 3, 4-tetrahydroquinoline, -isoquinoline, and -silaisoquinoline, and their trimethyland triethylsilyl derivatives and the corresponding methiodides were synthesized. The acute toxicity and psychotropic activity of the compounds synthesized were studied.

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