Shape-Dependent Control of Cell Growth, Differentiation, and Apoptosis: Switching between Attractors in Cell Regulatory Networks

Experimental Cell Research - Tập 261 Số 1 - Trang 91-103 - 2000
Sui Huang1, Donald E. Ingber1
1Department of Surgery, Department of Pathology, Children's Hospital and Harvard Medical School, Boston, Massachusetts, 02115

Tóm tắt

Từ khóa


Tài liệu tham khảo

Huang, 1999, The structural and mechanical complexity of cell-growth control, Nat. Cell Biol., 1, E131, 10.1038/13043

Lavoie, 1996, Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway, J. Biol. Chem., 271, 20608, 10.1074/jbc.271.34.20608

Terada, 1999, Regulation of cyclin D1 expression and cell cycle progression by mitogen-activated protein kinase cascade, Kidney Int., 56, 1258, 10.1046/j.1523-1755.1999.00704.x

Cheng, 1998, Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1), Proc. Natl. Acad. Sci. USA, 95, 1091, 10.1073/pnas.95.3.1091

Marais, 1996, Control of the ERK MAP kinase cascade by Ras and Raf, Cancer Surv., 27, 101

Fambrough, 1999, Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes, Cell, 97, 727, 10.1016/S0092-8674(00)80785-0

Coller, 2000, Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion, Proc. Natl. Acad. Sci. USA, 97, 3260, 10.1073/pnas.97.7.3260

Wang, 1995, R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism, J. Cell Biol., 129, 1103, 10.1083/jcb.129.4.1103

Mayo, 1997, Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras, Science, 278, 1812, 10.1126/science.278.5344.1812

Kauffmann-Zeh, 1997, Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB, Nature, 385, 544, 10.1038/385544a0

Chao, 1992, Growth factor signaling: Where is the specificity?, Cell, 68, 995, 10.1016/0092-8674(92)90068-N

Brunet, 1997, Mammalian MAP kinase modules: How to transduce specific signals, Essays Biochem., 32, 1

Shin, 1975, Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro, Proc. Natl. Acad. Sci. USA, 72, 4435, 10.1073/pnas.72.11.4435

Ingber, 1981, Role of basal lamina in neoplastic disorganization of tissue architecture, Proc. Natl. Acad. Sci. USA, 78, 3901, 10.1073/pnas.78.6.3901

Giancotti, 1999, Integrin signaling, Science, 285, 1028, 10.1126/science.285.5430.1028

Boudreau, 1998, Extracellular matrix signaling: Integration of form and function in normal and malignant cells, Curr. Opin. Cell Biol., 10, 640, 10.1016/S0955-0674(98)80040-9

Streuli, 1999, Extracellular matrix remodelling and cellular differentiation, Curr. Opin. Cell Biol., 11, 634, 10.1016/S0955-0674(99)00026-5

Aplin, 1999, Cell adhesion molecules, signal transduction and cell growth, Curr. Opin. Cell Biol., 11, 737, 10.1016/S0955-0674(99)00045-9

Frisch, 1997, Integrins and anoikis, Curr. Opin. Cell. Biol., 9, 701, 10.1016/S0955-0674(97)80124-X

Lin, 1997, Cell anchorage permits efficient signal transduction between ras and its downstream kinases, J. Biol. Chem., 272, 8849, 10.1074/jbc.272.14.8849

Zhu, 1995, Integrin-dependent activation of MAP kinase: A link to shape-dependent cell proliferation, Mol. Biol. Cell., 6, 273, 10.1091/mbc.6.3.273

Morino, 1995, Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2, J. Biol. Chem., 270, 269, 10.1074/jbc.270.1.269

Schwartz, 1997, Integrins, oncogenes, and anchorage independence, J. Cell. Biol., 139, 575, 10.1083/jcb.139.3.575

Singhvi, 1994, Engineering cell shape and function, Science, 264, 696, 10.1126/science.8171320

Chen, 1997, Geometric control of cell life and death, Science, 276, 1425, 10.1126/science.276.5317.1425

Huang, 1998, Cell-shape-dependent control of p27Kip and cell cycle progression in human capillary endothelial cells, Mol. Biol. Cell, 9, 3179, 10.1091/mbc.9.11.3179

Dike, 1999, Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates, In Vitro Cell Dev. Biol. Anim., 35, 441, 10.1007/s11626-999-0050-4

Folkman, 1978, Role of cell shape in growth control, Nature, 273, 345, 10.1038/273345a0

Li, 1987, Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells, Proc. Natl. Acad. Sci. USA, 84, 136, 10.1073/pnas.84.1.136

Ben-Ze'ev, 1988, Cell–cell and cell–matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes, Proc. Natl. Acad. Sci. USA, 85, 2161, 10.1073/pnas.85.7.2161

Mooney, 1992, Switching from differentiation to growth in hepatocytes: Control by extracellular matrix, J. Cell. Physiol., 151, 497, 10.1002/jcp.1041510308

Mochitate, 1991, Stress relaxation of contracted collagen gels: Disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis, Exp. Cell Res., 193, 198, 10.1016/0014-4827(91)90556-A

Bohmer, 1996, Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1, Mol. Biol. Cell, 7, 101, 10.1091/mbc.7.1.101

Assoian, 1997, Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression, Curr. Opin. Cell Biol., 9, 93, 10.1016/S0955-0674(97)80157-3

Ishizaki, 2000, Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases, Mol. Pharmacol., 57, 976

Lee, 1998, Extracellular matrix and pulmonary hypertension: Control of vascular smooth muscle cell contractility, Am. J. Physiol., 274, H76

Chicurel, 1998, Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions, Nature, 392, 730, 10.1038/33719

Chrzanowska-Wodnicka, 1996, Rho-stimulated contractility drives the formation of stress fibers and focal adhesions, J. Cell Biol., 133, 1403, 10.1083/jcb.133.6.1403

Rousseau, 1996, Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E, Proc. Natl. Acad. Sci. USA, 93, 1065, 10.1073/pnas.93.3.1065

Zhu, 1996, Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein, J. Cell Biol., 133, 391, 10.1083/jcb.133.2.391

Hesketh, 1994, Translation and the cytoskeleton: A mechanism for targeted protein synthesis, Mol. Biol. Rep., 19, 233, 10.1007/BF00986965

Bassell, 1994, Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts, J. Cell Biol., 126, 863, 10.1083/jcb.126.4.863

Chervitz, 1998, Comparison of the complete protein sets of worm and yeast: Orthology and divergence, Science, 282, 2022, 10.1126/science.282.5396.2022

Strohman, 1997, The coming Kuhnian revolution in biology, Nat. Biotechnol., 15, 194, 10.1038/nbt0397-194

Coffey, 1998, Self-organization, complexity and chaos: The new biology for medicine, Nat. Med., 4, 882, 10.1038/nm0898-882

Huang, 1999, Gene expression profiling, genetic networks and cellular states: An integrating concept for tumorigenesis and drug discovery, J. Mol. Med., 77, 469, 10.1007/s001099900023

Wolpert, 1994, Do we understand development?, Science, 266, 571, 10.1126/science.7939707

Kirschner, 1998, Evolvability, Proc. Natl. Acad. Sci. USA, 95, 8420, 10.1073/pnas.95.15.8420

Jacobson, 1993, Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA, Nature, 361, 365, 10.1038/361365a0

Hehner, 1999, Inhibition of tyrosine phosphatases induces apoptosis independent from the CD95 system, Cell Death Differ., 6, 833, 10.1038/sj.cdd.4400559

Yu, 1994, Dimethyl sulphoxide: A review of its applications in cell biology, Biosci. Rep., 14, 259, 10.1007/BF01199051

Spremulli, 1984, Polar solvents: A novel class of antineoplastic agents, J. Clin. Oncol., 2, 227, 10.1200/JCO.1984.2.3.227

Messing, 1993, Ethanol as an enhancer of neural differentiation, Alcohol Alcohol Suppl., 2, 289

Bogomolova, 1999, Morphological potential of Phaeococcomyces sp (strain ?h 49)—A typical representative of microcolonial lithobiontic fungi, Mikol. Fitopatol., 33, 95

Kulyk, 1996, Ethanol exposure stimulates cartilage differentiation by embryonic limb mesenchyme cells, Exp. Cell Res., 223, 290, 10.1006/excr.1996.0084

Somogyi, 1996, Modelling the complexity of genetic networks: Understanding multigenic and pleiotropic regulation, Complexity, 1, 45, 10.1002/cplx.6130010612

Kauffman, 1993

Thomas, 1995, Dynamical behaviour of biological regulatory networks. I. Biological role of feedback loops and practical use of the concept of loop-characteristic state, Bull. Math. Biol., 57, 247, 10.1007/BF02460618

Kaplan, 1995

Goss, 1967, The strategy of growth

Steinman, 1994, Induction of p21 (WAF-1/CIP1) during differentiation, Oncogene, 9, 3389

Parker, 1995, p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells, Science, 267, 1024, 10.1126/science.7863329

Das, 2000, MAPK-dependent expression of p21(WAF) and p27(kip1) in PMA-induced differentiation of HL60 cells, FEBS Lett., 472, 50, 10.1016/S0014-5793(00)01416-2

Jiang, 1995, The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells, Oncogene, 10, 1855

Huang, S. 2000, Cell state dynamics and tumorigenesis in Boolean regulatory networks. Submitted for publication.

Walsh, 1997, Cell cycle exit upon myogenic differentiation, Curr. Opin. Genet. Dev., 7, 597, 10.1016/S0959-437X(97)80005-6

Morrison, 1999, Insights into the transcriptional control of adipocyte differentiation, J. Cell. Biochem. Suppl., 32–33, 59, 10.1002/(SICI)1097-4644(1999)75:32+<59::AID-JCB8>3.0.CO;2-1

Dike, 1988, Cell adhesion induces expression of growth-associated genes in suspension-arrested fibroblasts, Proc. Natl. Acad. Sci. USA, 85, 6792, 10.1073/pnas.85.18.6792

Campisi, 1984, Kinetics of G1 transit following brief starvation for serum factors, Exp. Cell Res., 152, 459, 10.1016/0014-4827(84)90647-5

Raff, 1992, Social controls on cell survival and cell death, Nature, 356, 397, 10.1038/356397a0

Evan, 1998, A matter of life and cell death, Science, 281, 1317, 10.1126/science.281.5381.1317

O'Connor, 2000, Apoptosis and cell division, Curr. Opin. Cell. Biol., 12, 257, 10.1016/S0955-0674(99)00084-8

Schutte, 2000, Molecular switches that govern the balance between proliferation and apoptosis, Prog. Cell Cycle Res., 4, 207, 10.1007/978-1-4615-4253-7_18

Albert, 2000, Error and attack tolerance of complex networks, Nature, 406, 278, 10.1038/35019019

Bassett, 1999, Gene expression informatics—It's all in your mine, Nat. Genet., 21, 51, 10.1038/4478

Dutt, 2000, Proteomic analysis, Curr. Opin. Biotechnol., 11, 176, 10.1016/S0958-1669(00)00078-1

Serrano, 1997, Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16 lNK4a, Cell, 88, 593, 10.1016/S0092-8674(00)81902-9

Guttridge, 1999, NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1, Mol. Cell. Biol., 19, 5785, 10.1128/MCB.19.8.5785

Sha, 1998, Regulation of immune responses by NF-kappa B/Rel transcription factor, J. Exp. Med., 187, 143, 10.1084/jem.187.2.143

Baeuerle, 1998, Pro-inflammatory signaling: Last pieces in the NF-kappaB puzzle?, Curr. Biol., 8, R19, 10.1016/S0960-9822(98)70010-7

Mercurio, 1999, NF-kappaB as a primary regulator of the stress response, Oncogene, 18, 6163, 10.1038/sj.onc.1203174

Lipton, 1997, Janus faces of NF-kB: Neurodestruction versus neuroprotection, Nat. Med., 3, 20, 10.1038/nm0197-20

Beg, 1996, An essential role for NF-kappaB in preventing TNF-alpha-induced cell death, Science, 274, 782, 10.1126/science.274.5288.782

Traverse, 1992, Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor, Biochem. J., 288, 351, 10.1042/bj2880351

Cowley, 1994, Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells, Cell, 77, 841, 10.1016/0092-8674(94)90133-3

Schwartz, 1996, Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway, EMBO J., 15, 6525, 10.1002/j.1460-2075.1996.tb01043.x

Bornfeldt, 1997, The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells: Dependence on the availability of downstream targets, J. Clin. Invest., 100, 875, 10.1172/JCI119603

Pavlovic, 2000, Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic β-cells, Eur. Cytokine Netw., 11, 267

Xia, 1995, Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis, Science, 270, 1326, 10.1126/science.270.5240.1326

Verheij, 1996, Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis, Nature, 380, 75, 10.1038/380075a0

Almeida, 2000, Matrix survival signaling: From fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase, J. Cell Biol., 149, 741, 10.1083/jcb.149.3.741

Esteve, 1998, Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway, Oncogene, 17, 1855, 10.1038/sj.onc.1202082

Olson, 1998, Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1, Nature, 394, 295, 10.1038/28425

Olson, 1995, An essential role for Rho, Rac, and Cdc42 ATPases in cell cycle progression through G1, Science, 269, 1270, 10.1126/science.7652575

Day, 1997, Cell anchorage regulates apoptosis through the retinoblastoma tumor suppressor/E2F pathway, J. Biol. Chem., 272, 8125, 10.1074/jbc.272.13.8125

Harbour, 2000, Rb function in cell-cycle regulation and apoptosis, Nat. Cell Biol., 2, E65, 10.1038/35008695

Macleod, 1996, Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system, EMBO J., 15, 6178, 10.1002/j.1460-2075.1996.tb01006.x

Qin, 1994, Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis, Proc. Natl. Acad. Sci. USA, 91, 10918, 10.1073/pnas.91.23.10918

O'Reilly, 1997, Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo, J. Immunol., 159, 2301, 10.4049/jimmunol.159.5.2301

Maher, 1999, p38 mitogen-activated protein kinase activation is required for fibroblast growth factor-2-stimulated cell proliferation but not differentiation, J. Biol. Chem., 274, 17491, 10.1074/jbc.274.25.17491

Bobak, 1997, Inactivation of the small GTPase Rho disrupts cellular attachment and induces adhesion-dependent and adhesion-independent apoptosis, Oncogene, 18, 2170

Guan, 1996, Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4, Mol. Biol. Cell, 7, 57, 10.1091/mbc.7.1.57