Severe refractory thrombocytopenia in a woman positive for coronavirus disease 2019 with lupus and antiphospholipid syndrome

Lupus - Tập 29 Số 11 - Trang 1472-1474 - 2020
Alina Hayden1, Aishwarya Vyas-Lahar1, Vincent Rella2, Alla Rudinskaya3
1Department of Medicine, Norwalk Hospital, Western Connecticut Health Network, Norwalk, USA
2Department of Hematology and Oncology, Danbury Hospital, Western Connecticut Health Network, Norwalk, USA
3Section of Rheumatology, Western Connecticut Health Network, Danbury, USA

Tóm tắt

The coronavirus disease 2019 (COVID-19) pandemic has created new challenges that necessitate prompt responses in unexpected clinical situations. Multiple extrapulmonary manifestations and complications of COVID-19 have already been described, but only scattered data are present on immunologic manifestations. We present a case of severe refractory thrombocytopenia in a 51-year-old woman with a history of long-standing systemic lupus erythematosus and antiphospholipid syndrome who presented with hemoptysis in the setting of COVID-19 infection. The patient failed to respond to initial treatment with intravenous immunoglobulin, high-dose steroids, and platelet transfusion, but responded to eltrombopag, with prompt improvement of a platelet count. The current case report provides clinical data of relevance to the largely unexplored question of the immunologic complications of COVID-19 in patients with a pre-existing inflammatory state.

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Tài liệu tham khảo

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Lupus

Tập 29 Số 11

1472-1474

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