Serum autoantibody biomarkers for age-related macular degeneration and possible regulators of neovascularization

Experimental and Molecular Pathology - Tập 92 - Trang 64-73 - 2012
Kei Morohoshi1,2, Nishal Patel3, Masaharu Ohbayashi1,2, Victor Chong4, Hans E. Grossniklaus2, Alan C. Bird5, Santa J. Ono1,2
1Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital, Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
2Department of Ophthalmology, Emory University School of Medicine and Emory Eye Center, Dobbs Ocular Immunology Laboratories, Atlanta, GA, USA
3Institute of Ophthalmology, University College of London, London, UK
4Laser and Retinal Research Unit, King's College Hospital, London, UK
5Medical Retina Service, Moorfields Eye Hospital, London, UK

Tài liệu tham khảo

Ambati, 2003, Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies, Survey of Ophthalmology, 48, 257, 10.1016/S0039-6257(03)00030-4

An, 2006, Secreted proteome profiling in human RPE cell cultures derived from donors with age related macular degeneration and age matched healthy donors, Journal of Proteome Research, 5, 2599, 10.1021/pr060121j

Aprahamian, 2004, Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease, The Journal of Experimental Medicine, 199, 1121, 10.1084/jem.20031557

Asano, 2004, Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice, The Journal of Experimental Medicine, 200, 459, 10.1084/jem.20040342

Aslanian, 2006, Targeted disruption of the scavenger receptor and chemokine CXCL16 accelerates atherosclerosis, Circulation, 114, 583, 10.1161/CIRCULATIONAHA.105.540583

Brown, 1980, Localization of cyclic nucleotide phosphodiesterase in the multicellular stages of Dictyostelium discoideum, Differentiation, 16, 173, 10.1111/j.1432-0436.1980.tb01073.x

Clemons, 2005, Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19, Ophthalmology, 112, 533, 10.1016/j.ophtha.2004.10.047

Cousins, 2004, Monocyte activation in patients with age-related macular degeneration: a biomarker of risk for choroidal neovascularization?, Archives of Ophthalmology, 122, 1013, 10.1001/archopht.122.7.1013

Crabb, 2002, Drusen proteome analysis: an approach to the etiology of age-related macular degeneration, Proceedings of the National Academy of Sciences of the United States of America, 99, 14682, 10.1073/pnas.222551899

Cuadrado, 2006, Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome, Journal of Thrombosis and Haemostasis, 4, 2461, 10.1111/j.1538-7836.2006.02193.x

Dineen, 2006, A proposed rapid methodology to assess the prevalence and causes of blindness and visual impairment, Ophthalmic Epidemiology, 13, 31, 10.1080/09286580500473787

Dunaief, 2002, The role of apoptosis in age-related macular degeneration, Archives of Ophthalmology, 120, 1435, 10.1001/archopht.120.11.1435

Forger, 2004, Clinical significance of anti-dsDNA antibody isotypes: IgG/IgM ratio of anti-dsDNA antibodies as a prognostic marker for lupus nephritis, Lupus, 13, 36, 10.1191/0961203304lu485oa

Grossniklaus, 1992, Immunohistochemical and histochemical properties of surgically excised subretinal neovascular membranes in age-related macular degeneration, American Journal of Ophthalmology, 114, 464, 10.1016/S0002-9394(14)71859-8

Gu, 2003, Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration, The Journal of Biological Chemistry, 278, 42027, 10.1074/jbc.M305460200

Haines, 2005, Complement factor H variant increases the risk of age-related macular degeneration, Science, 308, 419, 10.1126/science.1110359

Hoffmann, 2005, Interaction between phosphatidylserine and the phosphatidylserine receptor inhibits immune responses in vivo, The Journal of Immunology, 174, 1393, 10.4049/jimmunol.174.3.1393

Joachim, 2006, Analysis of IgG antibody patterns against retinal antigens and antibodies to alpha-crystallin, GFAP, and alpha-enolase in sera of patients with “wet” age-related macular degeneration, Graefe's Archive for Clinical and Experimental Ophthalmology, 245, 619, 10.1007/s00417-006-0429-9

Kamei, 2007, Scavenger receptors for oxidized lipoprotein in age-related macular degeneration, Investigative Ophthalmology & Visual Science, 48, 1801, 10.1167/iovs.06-0699

Kremmer, 2001, Antiphosphatidylserine antibodies are elevated in normal tension glaucoma, Clinical and Experimental Immunology, 125, 211, 10.1046/j.1365-2249.2001.01578.x

Lambooij, 2003, Insulin-like growth factor-I and its receptor in neovascular age-related macular degeneration, Investigative Ophthalmology & Visual Science, 44, 2192, 10.1167/iovs.02-0410

Li, 2007, Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes, Clinical and Experimental Immunology, 147, 60, 10.1111/j.1365-2249.2006.03251.x

Mantel, 2008, Macular and retinal dysfunction of unknown origin in adults with normal fundi: evidence for an autoimmune pathophysiology, Experimental and Molecular Pathology, 84, 90, 10.1016/j.yexmp.2007.10.006

Matsuda, 1994, Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody, American Journal of Hematology, 47, 56, 10.1002/ajh.2830470112

Morohoshi, 2009, Autoimmunity in retinal degeneration: autoimmune retinopathy and age-related macular degeneration, Journal of Autoimmunity, 33, 247, 10.1016/j.jaut.2009.09.003

Mullins, 2000, Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease, The FASEB Journal, 14, 835, 10.1096/fasebj.14.7.835

Muraro, 2002, T cell response to 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) in multiple sclerosis patients, Journal of Neuroimmunology, 130, 233, 10.1016/S0165-5728(02)00229-1

Norgren, 2004, Neurofilament and glial fibrillary acidic protein in multiple sclerosis, Neurology, 63, 1586, 10.1212/01.WNL.0000142988.49341.D1

Otsuka, 2005, Phosphatidylserine-specific receptor contributes to TGF-beta production in macrophages through a MAP kinase, ERK, Biological & Pharmaceutical Bulletin, 28, 1707, 10.1248/bpb.28.1707

Patel, 2005, Circulating anti-retinal antibodies as immune markers in age-related macular degeneration, Immunology, 115, 422, 10.1111/j.1365-2567.2005.02173.x

Penfold, 1990, Autoantibodies to retinal astrocytes associated with age-related macular degeneration, Graefe's Archive for Clinical and Experimental Ophthalmology, 228, 270, 10.1007/BF00920033

Pierangeli, 1999, Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo, Circulation, 99, 1997, 10.1161/01.CIR.99.15.1997

Rampazzo, 2001, Some patients with antiphospholipid syndrome express hitherto undescribed antibodies to cardiolipin-binding proteins, Thrombosis and Haemostasis, 85, 57, 10.1055/s-0037-1612904

Rosenthal, 2004, Insulin-like growth factor-1 contributes to neovascularization in age-related macular degeneration, Biochemical and Biophysical Research Communications, 323, 1203, 10.1016/j.bbrc.2004.08.219

Sanna, 2000, Central nervous system involvement in systemic lupus erythematosus: cerebral imaging and serological profile in patients with and without overt neuropsychiatric manifestations, Lupus, 9, 573, 10.1191/096120300678828695

Simantov, 1995, Activation of cultured vascular endothelial cells by antiphospholipid antibodies, The Journal of Clinical Investigation, 96, 2211, 10.1172/JCI118276

Sivaprasad, 2005, Serum elastin-derived peptides in age-related macular degeneration, Investigative Ophthalmology & Visual Science, 46, 3046, 10.1167/iovs.04-1277

Suvajac, 2007, Ocular manifestations in antiphospholipid syndrome, Autoimmunity Reviews, 6, 409, 10.1016/j.autrev.2006.11.005

Umeda, 2005, Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (Macaca fascicularis), The FASEB Journal, 19, 1683, 10.1096/fj.04-3525fje

Vega-Ostertag, 2007, Role of p38 mitogen-activated protein kinase in antiphospholipid antibody-mediated thrombosis and endothelial cell activation, Journal of Thrombosis and Haemostasis, 5, 1828, 10.1111/j.1538-7836.2007.02680.x

Vogel, 1988, Molecular structure, localization, and possible functions of the myelin-associated enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase, Journal of Neurochemistry, 50, 1667, 10.1111/j.1471-4159.1988.tb02461.x

Walsh, 1998, Dual implication of 2′,3′-cyclic nucleotide 3′ phosphodiesterase as major autoantigen and C3 complement-binding protein in the pathogenesis of multiple sclerosis, The Journal of Clinical Investigation, 101, 1923, 10.1172/JCI1983