The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration
Tài liệu tham khảo
___: Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study Report Number 3. Ophthalmology 107:2224–32, 2000
___: A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntingtons disease chromosomes. The Huntingtons Disease Collaborative Research Group. Cell 72:971–83, 1993
___: Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group. Arch Ophthalmol 110:1701–8, 1992
Abecasis, 2004, Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease, Am J Hum Genet, 74, 482, 10.1086/382786
Allikmets, 1997, A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy, Nat Genet, 17, 122, 10.1038/ng0997-122b
Ambati, 2003, Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies, Surv Ophthalmol, 48, 257, 10.1016/S0039-6257(03)00030-4
Anderson, 2002, A role for local inflammation in the formation of drusen in the aging eye, Am J Ophthalmol, 134, 411, 10.1016/S0002-9394(02)01624-0
Anderson, 2004, Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration, Exp Eye Res, 78, 243, 10.1016/j.exer.2003.10.011
Anderson, 2005, Infection, antibiotics, and atherothrombosis—end of the road or new beginnings?, N Engl J Med, 352, 1706, 10.1056/NEJMe058019
Ashwell, 1974, The dual role of sialic acid in the hepatic recognition and catabolism of serum glycoproteins, Biochem Soc Symp, 40, 117
Blackmore, 1998, M protein of the group A Streptococcus binds to the seventh short consensus repeat of human complement factor H, Infect Immun, 66, 1427, 10.1128/IAI.66.4.1427-1431.1998
Blumenkranz, 1986, Risk factors in age-related maculopathy complicated by choroidal neovascularization, Ophthalmology, 93, 552, 10.1016/S0161-6420(86)33702-3
Botstein, 2003, Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease, Nat Genet, 33, 228, 10.1038/ng1090
Botto M: Links between complement deficiency and apopthsis. Arthritis Res 3:207–10, 200
Chaine, 1998, Case-control study of the risk factors for age related macular degeneration. France-DMLA Study Group, Br J Ophthalmol, 82, 996, 10.1136/bjo.82.9.996
Cho, 2000, Prospective study of alcohol consumption and the risk of age-related macular degeneration, Arch Ophthalmol, 118, 681, 10.1001/archopht.118.5.681
Clemons, 2005, Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19, Ophthalmology, 112, 533, 10.1016/j.ophtha.2004.10.047
Colville, 2003, Visual impairment caused by retinal abnormalities in mesangiocapillary (membranoproliferative) glomerulonephritis type II (dense deposit disease), Am J Kidney Dis, 42, E2, 10.1016/S0272-6386(03)00665-6
Congdon, 2004, Causes and prevalence of visual impairment among adults in the United States, Arch Ophthalmol, 122, 477, 10.1001/archopht.122.4.477
Cousins, 2004, Monocyte activation in patients with age-related macular degeneration: a biomarker of risk for choroidal neovascularization?, Arch Ophthalmol, 122, 1013, 10.1001/archopht.122.7.1013
Crabb, 2002, Drusen proteome analysis: an approach to the etiology of age-related macular degeneration, Proc Natl Acad Sci USA, 99, 14682, 10.1073/pnas.222551899
Daiger, 2004, Identifying retinal disease genes: how far have we come, how far do we have to go?, Novartis Found Symp, 255, 17, 10.1002/0470092645.ch3
Dasch, 2005, Inflammatory markers in age related maculopathy. Cross section anayysis from the Muenster Aging and Retina Study, Arch Ophthalmol, 123, 1501, 10.1001/archopht.123.11.1501
Davies, 2005, Modifier genes in cystic fibrosis, Pediatr Pulmonol, 39, 383, 10.1002/ppul.20198
DeAngelis, 2004, Extremely discordant sib-pair study design to determine risk factors for neovascular age-related macular degeneration, Arch Ophthalmol, 122, 575, 10.1001/archopht.122.4.575
Delves, 2000, The immune system. First of two parts, N Engl J Med, 343, 37, 10.1056/NEJM200007063430107
Delves, 2000, The immune system. Second of two parts, N Engl J Med, 343, 108, 10.1056/NEJM200007133430207
Donoso, 2001, Autosomal dominant Stargardt-like macular dystrophy, Surv Ophthalmol, 46, 149, 10.1016/S0039-6257(01)00251-X
Donoso, 2003, Clinical variability of Stickler syndrome: role of exon 2 of the collagen COL2A1 gene, Surv Ophthalmol, 48, 191, 10.1016/S0039-6257(02)00460-5
Donoso, 2003, Autosomal dominant macular dystrophy in a large Canadian family, Can J Ophthalmol, 38, 33, 10.1016/S0008-4182(03)80006-6
Dryja, 1997, Gene-based approach to human gene-phenotype correlations, Proc Natl Acad Sci USA, 94, 12117, 10.1073/pnas.94.22.12117
Dryja, 1997, Dominant and digenic mutations in the peripherin/RDS and ROM1 genes in retinitis pigmentosa, Invest Ophthalmol Vis Sci, 38, 1972
Dryja, 1990, Mutations within the rhodopsin gene in patients with autosomal dominant retinitis pigmentosa, N Engl J Med, 323, 1302, 10.1056/NEJM199011083231903
Duthy, 2002, The human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13 to 15, Infect Immun, 70, 5604, 10.1128/IAI.70.10.5604-5611.2002
Edwards AO, Ritter Iii R, Abel KJ, et al: Complement Factor H. Spolymorphism and age-related macular degenerationcience 10:10, 2005
Evans, 2001, Risk factors for age-related macular degeneration, Prog Retin Eye Res, 20, 227, 10.1016/S1350-9462(00)00023-9
Ewing, 2000, Analysis of expressed sequence tags indicates 35,000 human genes, Nat Genet, 25, 232, 10.1038/76115
Ferris, 1984, Age-related macular degeneration and blindness due to neovascular maculopathy, Arch Ophthalmol, 102, 1640, 10.1001/archopht.1984.01040031330019
Fine, 2005, Age-related macular degeneration 1969-2004: a 35-year personal perspective, Am J Ophthalmol, 139, 405, 10.1016/j.ajo.2004.11.050
Fishelson, 2001, Complement and apoptosis, Mol Immunol, 38, 207, 10.1016/S0161-5890(01)00055-4
Forrester, 1999, Immunopathogenic mechanisms in intraocular inflammation, Chem Immunol, 73, 159, 10.1159/000058745
Framme, 1998, [Subretinal neovascular membranes in membranoproliferative glomerulonephritis type II], Klin Monatsbl Augenheilkd, 213, 252, 10.1055/s-2008-1034983
Friedman, 2004, Prevalence of age-related macular degeneration in the United States, Arch Ophthalmol, 122, 564, 10.1001/archopht.122.4.564
Fung, 1987, Structural evidence for the authenticity of the human retinoblastoma gene, Science, 236, 1657, 10.1126/science.2885916
Garrod, 1902, The Incidence of Alkaptonuria: A study in chemical individuality, Lancet, 2, 1616, 10.1016/S0140-6736(01)41972-6
Gass, 1967, Pathogenesis of disciform detachment of the neuroepithelium, Am J Ophthalmol, 63, 1
Giannakis, 2003, A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein, Eur J Immunol, 33, 962, 10.1002/eji.200323541
Giannakis, 2002, Identification of the streptococcal M protein binding site on membrane cofactor protein (CD46), J Immunol, 168, 4585, 10.4049/jimmunol.168.9.4585
Giannakis, 2001, Multiple ligand binding sites on domain seven of human complement factor H, Int Immunopharmacol, 1, 433, 10.1016/S1567-5769(00)00040-0
Goldberg, 1996, Defective subunit assembly underlies a digenic form of retinitis pigmentosa linked to mutations in peripherin/rds and rom-1, Proc Natl Acad Sci USA, 93, 13726, 10.1073/pnas.93.24.13726
Goodrich, 1990, The molecular genetics of retinoblastoma, Cancer Surv, 9, 529
Gordon, 1995, Identification of complement regulatory domains in human factor H, J Immunol, 155, 348, 10.4049/jimmunol.155.1.348
Goverdhan, 2005, Association of HLA class I and class II polymorphisms with age-related macular degeneration, Invest Ophthalmol Vis Sci, 46, 1726, 10.1167/iovs.04-0928
Guymer, 2005, HMG CoA reductase inhibitors (statins): do they have a role in age-related macular degeneration?, Surv Ophthalmol, 50, 194, 10.1016/j.survophthal.2004.12.002
Haab, 1885, Erkankungen der Macula Lutea, Centralblat Augenheilkd, 9, 384
Hageman, 2005, A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration, Proc Natl Acad Sci USA, 102, 7227, 10.1073/pnas.0501536102
Hageman, 2001, An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruchs membrane interface in aging and age-related macular degeneration, Prog Retin Eye Res, 20, 705, 10.1016/S1350-9462(01)00010-6
Hageman, 1999, Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigmented epithelial cells, FASEB J, 13, 477, 10.1096/fasebj.13.3.477
Haines, 2005, Complement Factor H variant increases the risk of age-related macular degeneration, Science, 10, 419, 10.1126/science.1110359
Hansson, 2005, Inflammation, atherosclerosis, and coronary artery disease, N Engl J Med, 352, 1685, 10.1056/NEJMra043430
Hayashi, 2004, Evaluation of the ARMD1 locus on 1q25-31 in patients with age-related maculopathy: genetic variation in laminin genes and in exon 104 of HEMICENTIN-1, Ophthalmic Genet, 25, 111, 10.1080/13816810490514342
Heckenlively, 1999, Association of antiretinal antibodies and cystoid macular edema in patients with retinitis pigmentosa, Am J Ophthalmol, 127, 565, 10.1016/S0002-9394(98)00446-2
Heiba, 1994, Sibling correlations and segregation analysis of age-related maculopaty: The Beaver Dam Eye Study, Genet Epidemiol, 11, 51, 10.1002/gepi.1370110106
Helisalmi, 2004, Polymorphisms in neprilysin gene affect the risk of Alzheimers disease in Finnish patients, J Neurol Neurosurg Psychiatry, 75, 1746, 10.1136/jnnp.2004.036574
Huang, 2003, Peripheral drusen in membranoproliferative glomerulonephritis type II, Retina, 23, 429, 10.1097/00006982-200306000-00036
Hutchinson, 1875, Symmetrical central chorioretinal disease occurring in senile persons, R London Ophthalmol Hosp Rep, 8, 231
Hyman, 2000, Hypertension, cardiovascular disease, and age-related macular degeneration. Age-Related Macular Degeneration Risk Factors Study Group, Arch Ophthalmol, 118, 351, 10.1001/archopht.118.3.351
Jakobsdottir, 2005, Susceptibility genes for age-related maculopathy on chromosome 10q26, Am J Hum Genet, 77, 389, 10.1086/444437
Johnson, 2002, The Alzheimers A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration, Proc Natl Acad Sci USA, 99, 11830, 10.1073/pnas.192203399
Johnson, 2001, Complement activation and inflammatory processes in Drusen formation and age related macular degeneration, Exp Eye Res, 73, 887, 10.1006/exer.2001.1094
Johnson, 2000, A potential role for immune complex pathogenesis in drusen formation, Exp Eye Res, 70, 441, 10.1006/exer.1999.0798
Jozsi, 2004, Attachment of the soluble complement regulator factor H to cell and tissue surfaces: relevance for pathology, Histol Histopathol, 19, 251
Kajiwara, 1994, Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci, Science, 264, 1604, 10.1126/science.8202715
Kelm, 1996, The Sialoadhesins—a family of sialic acid-dependent cellular recognition molecules within the immunoglobulin superfamily, Glycoconj J, 13, 913, 10.1007/BF01053186
Kenealy, 2004, Linkage analysis for age-related macular degeneration supports a gene on chromosome 10q26, Mol Vis, 10, 57
Khoubian, 2005, Autosomal dominant pattern dystrophy: Identification of a novel splice site mutation in the peripherin/RDS gene, Retina, 25, 999, 10.1097/00006982-200512000-00008
Kini, 1978, Prevalence of senile cataract, diabetic retinopathy, senile macular degneration, and open-angle glaucoma in the Framingham eye study, Am J Ophthalmol, 85, 28, 10.1016/S0002-9394(14)76661-9
Klaver, 1998, Genetic association of apolipoprotein E with age-related macular degeneration, Am J Hum Genet, 63, 200, 10.1086/301901
Klaver, 1998, Genetic risk of age-related maculopathy. Population-based familial aggregation study, Arch Ophthalmol, 116, 1646, 10.1001/archopht.116.12.1646
Klein, 1994, Heredity and age-related macular degeneration. Observations in monozygotic twins, Arch Ophthalmol, 112, 932, 10.1001/archopht.1994.01090190080025
Klein, 1998, Age-related macular degeneration. Clinical features in a large family and linkage to chromosome 1q, Arch Ophthalmol, 116, 1082, 10.1001/archopht.116.8.1082
Klein, 1999, Prevalence of age-related maculopathy in the Atherosclerosis Risk in Communities Study, Arch Ophthalmol, 117, 1203, 10.1001/archopht.117.9.1203
Klein, 2003, Early age-related maculopathy in the cardiovascular health study, Ophthalmology, 110, 25, 10.1016/S0161-6420(02)01565-8
Klein, 2003, Association of emphysema, gout, and inflammatory markers with long-term incidence of age-related maculopathy, Arch Ophthalmol, 121, 674, 10.1001/archopht.121.5.674
Klein, 2005, Complement Factor H polymorphism in age-related macular degeneration, Science, 10, 385, 10.1126/science.1109557
Kornzweig, 1965, The eye in old age V. Diseases of the macula: a clinicopathologic study, Am J Ophthalmol, 60, 835, 10.1016/0002-9394(65)92002-7
Kotarsky, 1998, Identification of a domain in human factor H and factor H-like protein-1 required for the interaction with streptococcal M proteins, J Immunol, 160, 3349, 10.4049/jimmunol.160.7.3349
Lai, 2001, Application of SNP technologies in medicine: lessons learned and future challenges, Genome Res, 11, 927, 10.1101/gr.192301
Lander, 2001, Initial sequencing and analysis of the human genome, Nature, 409, 860, 10.1038/35057062
Lee, 1987, Human retinoblastoma susceptibility gene: cloning, identification, and sequence, Science, 235, 1394, 10.1126/science.3823889
Lerner, 1995, Immunological mimicry between retinal S-antigen and group A streptococcal M proteins, Autoimmunity, 22, 95, 10.3109/08916939508995305
Levinson, 2002
MacDonald, 1994, Molecular genetics of inherited eye disorders, Clin Invest Med, 17, 474
MacDonald, 2004, Ocular genetics: current understanding, Surv Ophthalmol, 49, 159, 10.1016/j.survophthal.2003.12.003
Majewski, 2003, Age-related macular degeneration—a genome scan in extended families, Am J Hum Genet, 73, 540, 10.1086/377701
Marmorstein, 2004, Association of EFEMP1 with malattia leventinese and age-related macular degeneration: a mini-review, Ophthalmic Genet, 25, 219, 10.1080/13816810490498305
McGeer, 2004, Inflammation and the degenerative diseases of aging, Ann NY Acad Sci, 1035, 104, 10.1196/annals.1332.007
McGwin, 2005, The relation between C reactive protein and age related macular degeneration in the Cardiovascular Health Study, Br J Ophthalmol, 89, 1166, 10.1136/bjo.2005.067397
Mendel, 1866, Versuche tiber Pflanzen-Hybriden, Verhandlungen des naturforschendend Vereines in Brunn, 4, 3
Meyers, 1995, A twin study of age-related macular degeneration, Am J Ophthalmol, 120, 757, 10.1016/S0002-9394(14)72729-1
Michaelides, 2003, The genetics of inherited macular dystrophies, J Med Genet, 40, 641, 10.1136/jmg.40.9.641
Miller, 2004, The association of prior cytomegalovirus infection with neovascular age-related macular degeneration, Am J Ophthalmol, 138, 323, 10.1016/j.ajo.2004.03.018
Mold, 1999, Regulation of complement activation by C-reactive protein, Immunopharmacology, 42, 23, 10.1016/S0162-3109(99)00007-7
Mold, 1984, C-reactive protein inhibits pneumococcal activation of the alternative pathway by increasing the interaction between factor H and C3b, J Immunol, 133, 882, 10.4049/jimmunol.133.2.882
Morell, 1971, The role of sialic acid in determining the survival of glycoproteins in the circulation, J Biol Chem, 246, 1461, 10.1016/S0021-9258(19)76994-4
Mullins, 2001, Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis, Eye, 15, 390, 10.1038/eye.2001.142
Mullins, 2000, Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease, FASEB J, 14, 835, 10.1096/fasebj.14.7.835
Nathans, 1989, Molecular genetics of human blue cone monochromacy, Science, 245, 831, 10.1126/science.2788922
Nathans, 1993, Genetic heterogeneity among blue-cone monochromats, Am J Hum Genet, 53, 987
Nettleship, 1884, Central areolar choroidal atrophy, Trans Ophthalmol Soc UK, 4, 165
Nichols, 1993, A 2 base pair deletion in the RDS gene associated with butterfly-shaped pigment dystrophy of the fovea, Hum Mol Genet, 2, 6013
Nichols, 1993, Butterfly-shaped pigment dystrophy of the fovea caused by a point mutation in codon 167 of the RDS gene, Nat Genet, 3, 202, 10.1038/ng0393-202
Niculescu, 2004, The role of complement activation in atherosclerosis, Immunol Res, 30, 73, 10.1385/IR:30:1:073
Pager, 2001, Malattia leventinese presenting with subretinal neovascular membrane and hemorrhage, Am J Ophthalmol, 131, 517, 10.1016/S0002-9394(00)00821-7
Penfold, 2001, Immunological and aetiological aspects of macular degeneration, Prog Retin Eye Res, 20, 385, 10.1016/S1350-9462(00)00025-2
Petrukhin, 1998, Identification of the gene responsible for Best macular dystrophy, Nat Genet, 19, 241, 10.1038/915
Piguet, 1993, Age-related Bruchs membrane change: a clinical study of the relative role of heredity and environment, Br J Ophthalmol, 77, 400, 10.1136/bjo.77.7.400
Ramanathan, 2002, Functional cloning, sorting, and expression profiling of nucleic acid-binding proteins, Genome Res, 12, 1175, 10.1101/gr.156002
Ramensky, 2002, Human non-synonymous SNPs: server and survey, Nucleic Acids Res, 30, 3894, 10.1093/nar/gkf493
Ripoche, 1988, The complete amino acid sequence of human complement factor H, Biochem J, 249, 593, 10.1042/bj2490593
Ripoche, 1988, Two populations of complement factor H differ in their ability to bind to cell surfaces, Biochem J, 253, 475, 10.1042/bj2530475
Rodríguez de Córdoba, 2004, The human complement factor H: functional roles, genetic variations and disease associations, Mol Immunol, 41, 355, 10.1016/j.molimm.2004.02.005
Royer-Pokora, 1986, Cloning the gene for the inherited disorder chronic granulomatous disease on the basis of its chromosomal location, Cold Spring Harb Symp Quant Biol, 51, 177, 10.1101/SQB.1986.051.01.021
Russell, 2000, Location, substructure, and composition of basal laminar drusen compared with drusen associated with aging and age-related macular degeneration, Am J Ophthalmol, 129, 205, 10.1016/S0002-9394(99)00345-1
Sauer, 1997, Positional cloning of the gene associated with X-linked juvenile retinoschisis, Nat Genet, 17, 164, 10.1038/ng1097-164
Schick, 2003, A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study, Am J Hum Genet, 72, 1412, 10.1086/375500
Schmidt, 2002, A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy, Ophthalmic Genet, 23, 209, 10.1076/opge.23.4.209.13883
Schultz, 2003, Lack of an association of apolipoprotein E gene polymorphisms with familial age-related macular degeneration, Arch Ophthalmol, 121, 679, 10.1001/archopht.121.5.679
Schultz, 2003, Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family, Hum Mol Genet, 12, 3315, 10.1093/hmg/ddg348
Seddon, 2005, The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences, Arch Ophthalmol, 123, 321, 10.1001/archopht.123.3.321
Seddon, 2004, Association between C-reactive protein and age-related macular degeneration, JAMA, 291, 704, 10.1001/jama.291.6.704
Seddon, 2003, A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions, Am J Hum Genet, 73, 780, 10.1086/378505
Silvestri, 1997, Age-related macular degeneration: genetics and implications for detection and treatment, Mol Med Today, 3, 84, 10.1016/S1357-4310(96)10057-5
Simonelli, 2001, Apolipoprotein E polymorphisms in age-related macular degeneration in an Italian population, Ophthalmic Res, 33, 325, 10.1159/000055688
Singh, 2001, Prevalence of and risk factors for abdominal aortic aneurysms in a population-based study: The Tromsø Study, Am J Epidemiol, 154, 236, 10.1093/aje/154.3.236
Small, 1992, North Carolina macular dystrophy is assigned to chromosome 6, Genomics, 13, 681, 10.1016/0888-7543(92)90141-E
Smiddy, 1984, Prognosis of patients with bilateral macular drusen, Ophthalmology, 91, 271, 10.1016/S0161-6420(84)34309-3
Smith, 2001, Risk factors for age-related macular degeneration: pooled findings from three continents, Ophthalmology, 108, 697, 10.1016/S0161-6420(00)00580-7
Smith, 2000, Dietary fat an fish intake and age-related maculopathy, Arch Ophthalmol, 118, 401, 10.1001/archopht.118.3.401
Souied, 1998, The epsilon4 allele of the apolipoprotein E gene as a potential protective factor for exudative age-related macular degeneration, Am J Ophthalmol, 125, 353, 10.1016/S0002-9394(99)80146-9
Stone, 2004, Missense variations in the fibulin 5 gene and age-related macular degeneration, N Engl J Med, 351, 346, 10.1056/NEJMoa040833
Stone, 1999, A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy, Nat Genet, 22, 199, 10.1038/9722
Tantri, 2004, X-linked retinoschisis: a clinical and molecular genetic review, Surv Ophthalmol, 49, 214, 10.1016/j.survophthal.2003.12.007
Tomany, 2004, Risk factors for incident age-related macular degeneration: pooled findings from 3 continents, Ophthalmology, 111, 1280, 10.1016/j.ophtha.2003.11.010
Traboulsi, 2005, The challenges and surprises of studying the genetics of age-related macular degeneration, Am J Ophthalmol, 139, 908, 10.1016/j.ajo.2005.01.045
Tuo, 2004, Genetic factors of age-related macular degeneration, Prog Retin Eye Res, 23, 229, 10.1016/j.preteyeres.2004.02.001
van Leeuwen, 2003, The risk and natural course of age-related maculopathy: follow-up at 6 1/2 years in the Rotterdam study, Arch Ophthalmol, 121, 519, 10.1001/archopht.121.4.519
Van Lenten, 1971, Studies on the chemical and enzymatic modification of glycoproteins. A general method for the tritiation of sialic acid-containing glycoproteins, J Biol Chem, 246, 1889, 10.1016/S0021-9258(18)62392-0
Vingerling, 1995, Age-related macular degeneration is associated with atherosclerosis, The Rotterdam Study. Am J Epidemiol, 142, 404, 10.1093/oxfordjournals.aje.a117648
Walport, 2001, Complement. First of two parts, N Engl J Med, 344, 1058, 10.1056/NEJM200104053441406
Walport, 2001, Complement. Second of two parts, N Engl J Med, 344, 1140, 10.1056/NEJM200104123441506
Wang, 2003, Risk of age-related macular degeneration in eyes with macular drusen or hyperpigmentation: the Blue Mountains Eye Study cohort, Arch Ophthalmol, 121, 658, 10.1001/archopht.121.5.658
Weber, 1994, Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsbys fundus dystrophy, Nat Genet, 8, 352, 10.1038/ng1294-352
Weeks, 2004, Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions, Am J Hum Genet, 75, 174, 10.1086/422476
Weleber, 1993, Phenotypic variation including retinitis pigmentosa, pattern dystrophy, and fundus flavimaculatus in a single family with a deletion of codon 153 or 154 of the peripherin/RDS gene, Arch Ophthalmol, 111, 1531, 10.1001/archopht.1993.01090110097033
Wells, 1993, Mutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophy, Nat Genet, 3, 213, 10.1038/ng0393-213
Wildner, 2004, Autoimmune uveitis and antigenic mimicry of environmental antigens, Autoimmun Rev, 3, 383, 10.1016/j.autrev.2004.01.002
Zack, 1999, What can we learn about age-related macular degeneration from other retinal diseases, Molecular Vision, 5, 30
Zarbin, 2004, Current concepts in the pathogenesis of age-related macular degeneration, Arch Ophthalmol, 122, 598, 10.1001/archopht.122.4.598
Zhang, 2001, A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy, Nat Genet, 27, 89, 10.1038/84765
Zimmerman, 1979, Metastatic disease from untreated uveal melanomas, Am J Ophthalmol, 88, 524, 10.1016/0002-9394(79)90658-5
Zipfel, 2001, Complement factor H: physiology and pathophysiology, Semin Thromb Hemost, 27, 191, 10.1055/s-2001-15248
Zipfel, 1999, Factor H and disease: a complement regulator affects vital body functions, Mol Immunol, 36, 241, 10.1016/S0161-5890(99)00038-3
Zipfel, 2002, Factor H family proteins: on complement, microbes and human diseases, Biochem Soc Trans, 30, 971, 10.1042/bst0300971