Screening for symptoms of depression and anxiety in adolescents and young adults with cystic fibrosis

Pediatric Pulmonology - Tập 46 Số 2 - Trang 153-159 - 2011
Avani C. Modi1, Kimberly A. Driscoll2, Karen Montag‐Leifling3, James D. Acton3
1Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA
2Florida State University College of Medicine, Department of Medical Humanities & Social Sciences, Tallahassee, Florida
3Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio

Tóm tắt

AbstractBackgroundAlthough studies have assessed symptoms of depression and anxiety in individuals with cystic fibrosis (CF), few have been conducted since the advent of new medical treatments (e.g., nebulized antibiotics, ThAIRpy Vest). Study objectives were to: (1) document symptoms of depression and anxiety for adolescents and young adults with CF and compare with normative values, (2) examine the associations among depressive/anxiety symptoms and gender, age, lung function, and body mass index, and (3) determine the relations between adolescent and caregiver symptoms of depression and anxiety.MethodsPatients and caregivers completed the Hospital Anxiety and Depression Scale (HADS) anytime (e.g., beginning or end) during routine CF clinic appointments.ResultsParticipants included 59 adolescents/young adults with CF (Mage = 15.8 years, 54% female, 98% Caucasian, MFEV1% predicted = 84.6) and caregivers of 40 adolescents. Although symptom scores were in the normative range for patients with CF (MDepression = 2.27 and MAnxiety = 5.59), 3% and 32% exhibited clinically elevated symptoms of depression and anxiety, respectively. Symptoms of depression and anxiety were significantly associated with age (r = 0.28, 0.36). Symptoms of depression and anxiety were also positively correlated (r = 0.48). Females endorsed higher anxiety symptoms than males. While adolescent and caregiver anxiety scores were not related, higher caregiver depressive symptoms were associated with older patient age and worse lung function.ConclusionsData from the current study suggest low levels of depressive symptoms and substantial levels of anxiety symptoms in adolescents and young adults with CF. Consistent with prior literature, depressive symptoms appear higher in older patients and are significantly associated with anxiety symptoms. Caregiver symptomology appears to be more affected by an adolescent's health status, suggesting a need to screen caregivers when health begins to decline. Pediatr. Pulmonol. 2011; 46:153–159. © 2011 Wiley‐Liss, Inc.

Từ khóa


Tài liệu tham khảo

Cystic Fibrosis Foundation.About Cystic Fibrosis.2009; Accessed on December 29 2009 atwww.cff.org/AboutCF/.

10.1378/chest.06-2474

10.1093/jpepsy/jsg044

10.1097/MCP.0b013e3283121cf1

10.1055/s-0029-1238915

10.1207/s15374424jccp2404_3

10.1001/archpsyc.62.6.593

10.1097/00004583-199103000-00019

10.1097/00004583-199612000-00008

10.1002/ppul.20090

10.1037/0021-843X.109.2.345

10.1542/peds.2008-2415

Association AP, 2000, Diagnostic and statistical manual of mental disorders

10.1002/ppul.21238

10.1111/j.1651-2227.2006.00014.x

10.1002/da.1068

10.1176/ajp.150.12.1779

10.1037/0033-2909.111.2.244

Rohde P, 1991, Comorbidity of unipolar depression: II. Comorbidity with other mental disorders in adolescents and adults, J Abnorm Psychol, 100, 214, 10.1037/0021-843X.100.2.214

10.1016/j.jcf.2008.05.010

10.1007/s00787-008-0709-5

10.1207/s15326888chc3501_4

10.1016/j.jcf.2008.05.002

10.1002/ppul.21057

10.1097/00004583-199603000-00008

10.1542/peds.104.6.1274

10.2337/dc07-0603

10.1176/ajp.2006.163.6.1001

10.1111/j.1600-0447.1983.tb09716.x

10.1348/014466501163904

10.1093/oxfordjournals.aje.a009172

10.1093/aje/153.4.345

10.1176/appi.ajp.162.2.250

10.1097/00004703-199402000-00004

10.1016/S0165-0327(98)00084-6

10.1136/thx.2006.061366

10.1080/02739610701766925

Beck A, 1996, Manual for beck depression inventory II (BDI‐II)