Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity
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Asakawa, 1977, 13C NMR study of ginseng sapogenins and their related dammarane type triterpenes, Tetrahedron, 33, 1935, 10.1016/0040-4020(77)80379-7
Baek, 1996, Ginsenoside Rh-4, a genuine dammarane glycoside from Korean red ginseng, Planta Med., 62, 86, 10.1055/s-2006-957816
Baek, 1997, Ginsenoside Rs3, a genuine dammarane-glycoside from Korean red ginseng, Arch. Pharm. Res., 20, 280, 10.1007/BF02976158
Baek, 2012, Recent methodology in Ginseng analysis, J. Ginseng Res., 36, 119, 10.5142/jgr.2012.36.2.119
Besso, 1982, Further studies on dammarane-saponins of American Ginseng, roots of Panax quinquefolium L., Chem. Pharm. Bull., 30, 4534, 10.1248/cpb.30.4534
Besso, 1982, Ginsenoside-Ra1 and ginsenoside-Ra2, new dammarane-saponins of Ginseng roots, Chem. Pharm. Bull., 30, 2380, 10.1248/cpb.30.2380
Chan, 2011, Bioactive constituents from the roots of Panax japonicus var. major and development of a LC–MS/MS method for distinguishing between natural and artifactual compounds, J. Nat. Prod., 74, 796, 10.1021/np100851s
Chen, 1987, Studies on new minor saponins isolated from leaves of Panax ginseng C.A. Meyer, Acta Pharm. Sin., 9, 685
Chen, 1988, Isolation and identification of the anti-tumor constituent, ginsenoside-Rh2, Zhong Yao Tong Bao, 13, 40
Chen, 1990, Isolation and elucidation of a new minor saponin from the leaves of Panax ginseng C.A. Meyer, Acta Pharm. Sin., 25, 379
Chen, 2006, New dammarane monodesmosides from the acidic deglycosylation of notoginseng-leaf saponins, Helv. Chim. Acta, 89, 1442, 10.1002/hlca.200690144
Chen, 2008, Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium, Acta Pharmacol. Sin., 29, 1103, 10.1111/j.1745-7254.2008.00868.x
Chen, 2009, Three new triterpenoid saponins from the leaves and stems of Panax quinquefolium, J. Asian Nat. Prod. Res., 11, 195, 10.1080/10286020802682734
Cho, 2010, Physicochemical characterization and NMR assignments of ginsenosides Rb1, Rb2, Rc, and Rd isolated from Panax ginseng, J. Ginseng Res., 34, 113, 10.5142/jgr.2010.34.2.113
Cui, 2008, Two new dammarane triterpene glycosides from the rhizomes of Panax notoginseng, J. Asian Nat. Prod. Res., 10, 845, 10.1080/10286020802144776
Dou, 1996, A novel minor saponin from the leaves of Panax ginseng C.A. Meyer, J. Chin. Pharm. Sci., 5, 48
Dou, 1996, Ginsenoside-La: a novel minor saponin from the leaves of Panax ginseng, Planta Med., 62, 179, 10.1055/s-2006-957849
Dou, 2001, Six new dammarane-type triterpene saponins from the leaves of Panax ginseng, Chem. Pharm. Bull., 49, 442, 10.1248/cpb.49.442
Dou, 2006, Ginsenoside Rg8, a new dammarane-type triterpenoid saponin from roots of Panax quinquefolium, Chem. Pharm. Bull., 54, 751, 10.1248/cpb.54.751
Duc, 1993, Saponins from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. I, Chem. Pharm. Bull., 41, 2010, 10.1248/cpb.41.2010
Duc, 1994, Saponins from Vietnamese Ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam. II, Chem. Pharm. Bull., 42, 115, 10.1248/cpb.42.115
Duc, 1994, Saponins from Vietnamese Ginseng, Panax vietnamensis Ha et Grushv. Collected in central Vietnam III, Chem. Pharm. Bull., 42, 634, 10.1248/cpb.42.634
Duc, 1999, New dammarane saponins from Vietnamese ginseng, Stud. Plant Sci., 6, 77, 10.1016/S0928-3420(99)80010-X
Feng, 1987, Dammarane saponins of leaves of Panax japonicus var. major collected in Qinling Mountain, China (1), Acta Bot. Yunnanica, 9, 477
Jia, 2008, Two new acetylated ginsenosides from the roots of Panax quinquefolium, Chin. Chem. Lett., 19, 1099, 10.1016/j.cclet.2008.06.033
Jiang, 2008, Structure elucidation and complete NMR spectral assignments of two new dammarane-type tetraglycosides from Panax quinquefolium, Magn. Reson. Chem., 46, 786, 10.1002/mrc.2247
Kaku, 1980, Isolation and characterization of ginsenoside Rg2, 20R-prosapogenin, 20S-prosapogenin and Δ20-prosapogenin. Chemical studies on saponins of Panax ginseng C.A. Meyer. Third report, Arzneimittelforschung, 30, 936
Kasai, 1977, C-13 chemical-shifts of isoprenoid-beta-d-glucopyranosides and isoprenoid-beta-d-mannopyranosides – stereochemical influences of aglycone alcohols, Tetrahedron Lett., 2, 175, 10.1016/S0040-4039(01)92581-X
Keum, 2000, Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng, Cancer Lett., 150, 41, 10.1016/S0304-3835(99)00369-9
Kim, 1995, Dammarane saponins from Panax ginseng, Phytochemistry, 40, 1493, 10.1016/0031-9422(95)00218-V
Kim, 1996, Ginsenoside Rg5, a genuine dammarane glycoside from Korean red ginseng, Arch. Pharm. Res., 19, 551, 10.1007/BF02986026
Kim, 2000, Steaming of ginseng at high temperature enhances biological activity, J. Nat. Prod., 63, 1702, 10.1021/np990152b
Kitagawa, 1981, Chemical studies on crude drugs. I. On the constituents of ginseng radix rubra, Yakugaku Zasshi, 103, 612, 10.1248/yakushi1947.103.6_612
Kitagawa, 1983, Malonyl-ginsenoside Rb1, Rb2, Rc, and Rd, four new malonylated dammarane-type triterpene oligoglycosides from ginseng radix, Chem. Pharm. Bull., 31, 3353, 10.1248/cpb.31.3353
Kohda, 1991, Chikusetsusaponin. VI. A new saponin from the rhizome of Panax pseudo-ginseng var. angustatus Hara, Chem. Pharm. Bull., 39, 1588, 10.1248/cpb.39.1588
Komakine, 2006, New dammarane-type saponin from roots of Panax notoginseng, J. Nat. Med., 60, 135, 10.1007/s11418-005-0016-0
Leung, 2010, Pharmacology of ginsenosides: a literature review, Chin. Med., 5, 20, 10.1186/1749-8546-5-20
Li, 2001, A novel hexanordammarane glycoside from the roots of Panax notoginseng, Chin. Chem. Lett., 12, 59
Li, 2009, A new triterpenoid saponin from the leaves and stems of Panax quinquefolium L., Chin. Chem. Lett., 20, 1207, 10.1016/j.cclet.2009.05.017
Li, 2012, New triterpenoids from the stems and leaves of Panax ginseng, Fitoterapia, 83, 1030, 10.1016/j.fitote.2012.05.013
Li, 2012, Four new dammarane-type triterpene saponins from the stems and leaves of Panax ginseng and their cytotoxicity on HL-60 cells, Planta Med., 78, 189, 10.1055/s-0031-1280320
Liang, 2010, Oleanane-type triterpenoids from Panax stipuleanatus and their anticancer activities, Bioorg. Med. Chem. Lett., 20, 7110, 10.1016/j.bmcl.2010.09.074
Liao, 2008, Dammarane-type glycosides from steamed notoginseng, J. Agric. Food Chem., 56, 1751, 10.1021/jf073000s
Lin, 1976, Studies on the constituents of Panacis Japonici Rhizoma. V. The structures of chikusetsusaponin I, Ia, Ib, Iva and glycoside P1, Chem. Pharm. Bull., 24, 253, 10.1248/cpb.24.253
Liu, 2007, A new semisynthetic octillol-type saponin and resuscitation of haemorrhagic shock, J. Asian Nat. Prod. Res., 9, 103, 10.1080/10286020500251741
Liu, 2009, Identification of new trace triterpenoid saponins from the roots of Panax notoginseng by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry, Rapid Commun. Mass Spectrom., 23, 667, 10.1002/rcm.3917
Liu, 2010, Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer, J. Asian Nat. Prod. Res., 12, 865, 10.1080/10286020.2010.508035
Lu, 2008, Effect and mechanism of ginsenoside Rg3 on postoperative life span of patients with non-small cell lung cancer, Chin. J. Integr. Med., 14, 33, 10.1007/s11655-007-9002-6
Lu, 2012, Quinquenoside F6, a new triterpenoid saponin from the fruits of Panax quinquefolium L., Nat. Prod. Res., 26, 1395, 10.1080/14786419.2011.592833
Ma, 1999, Saponins from the roots of Panax notoginseng, Phytochemistry, 52, 1133, 10.1016/S0031-9422(99)00364-7
Ma, 2012, Three new triterpenoids from Panax ginseng exhibit cytotoxicity against human A549 and Hep-3B cell lines, J. Nat. Med., 66, 576, 10.1007/s11418-012-0662-y
Mao, 2012, Target separation of a new anti-tumor saponin and metabolic profiling of leaves of Panax notoginseng by liquid chromatography with electrospray ionization quadrupole time-of-flight mass spectrometry, J. Pharm. Biomed. Anal., 59, 67, 10.1016/j.jpba.2011.10.004
Matsuura, 1983, Further studies on dammarane-saponins of sanchi ginseng, Chem. Pharm. Bull., 31, 2281, 10.1248/cpb.31.2281
Matsuura, 1984, Further studies on dammarane-saponins of Ginseng roots, Chem. Pharm. Bull., 32, 1188, 10.1248/cpb.32.1188
Morita, 1982, Saponins of Zu-Tziseng, rhizomes of Panax japonicus C.A. Meyer var. major (Burk.) C. Y. Wu et K. M. Feng, collected in Yunnan, China, Chem. Pharm. Bull., 30, 4341, 10.1248/cpb.30.4341
Morita, 1986, Saponins of plants of Panax species collected in central Nepal and their chemotaxonomical significance. II, Chem. Pharm. Bull., 34, 4368, 10.1248/cpb.34.4368
Nagai, 1971, Chemical studies on the oriental plant drugs-XXIV: structure of ginsenoside-Rg1, a neutral saponin of ginseng root, Tetrahedron, 27, 881, 10.1016/S0040-4020(01)92488-3
Nagai, 1972, Chemical studies on the oriental plant drugs. XXVIII. Saponins and sapogenins of Ginseng: stereochemistry of the sapogenin of ginsenosides-Rb1, -Rb2, and -Rc, Chem. Pharm. Bull., 20, 1212, 10.1248/cpb.20.1212
Nakamura, 2007, Medicinal flowers. XVII. New dammarane-type triterpene glycoside from flower buds of American Ginseng, Panax quinquefolium L., Chem. Pharm. Bull., 55, 1342, 10.1248/cpb.55.1342
Nakamura, 2007, Structures of dammarane-type triterpene triglycosides from flower buds of Panax ginseng, Heterocycles, 71, 577, 10.3987/COM-06-10959
Namba, 1986, Saponins of plants of Panax species collected in central Nepal and their chemotaxonomical significance. I, Chem. Pharm. Bull., 34, 730, 10.1248/cpb.34.730
Ng, 2006, Pharmacological activity of sanchi ginseng (Panax notoginseng), J. Pharm. Pharmacol., 58, 1007, 10.1211/jpp.58.8.0001
Nguyen, 2010, New dammarane saponins from the steamed ginseng leaves, Bull. Korean Chem. Soc., 31, 2094, 10.5012/bkcs.2010.31.7.2094
Park, 1998, Ginsenoside Rf2, a new dammarane glycoside from Korean red ginseng (Panax ginseng), Arch. Pharm. Res., 21, 615, 10.1007/BF02975384
Park, 2002, Four new acetylated ginsenosides from processed ginseng (Sun Ginseng), Arch. Pharm. Res., 25, 837, 10.1007/BF02977001
Park, 2002, Three new dammarane glycosides from heat processed ginseng, Arch. Pharm. Res., 25, 428, 10.1007/BF02976595
Park, 2012, Ginseng in traditional herbal prescriptions, J. Ginseng Res., 36, 225, 10.5142/jgr.2012.36.3.225
Qi, 2011, Isolation and analysis of ginseng: advances and challenges, Nat. Prod. Rep., 28, 467, 10.1039/c0np00057d
Qiu, 1998, Studies on dammarane-type saponins in the flower-buds of Panax ginseng C.A. Meyer, J. Asian Nat. Prod. Res., 1, 119, 10.1080/10286029808039853
Qiu, 2001, A pair of 24-hydroperoxyl epimeric dammarane saponins from flower-buds of Panax ginseng, J. Asian Nat. Prod. Res., 3, 235, 10.1080/10286020108041396
Qiu, 2009, Dammarane-type saponins from Panax quinquefolium and their inhibition activity on human breast cancer MCF-7 cells, Fitoterapia, 80, 219, 10.1016/j.fitote.2009.01.011
Ruan, 2010, Isolation and characterization of a new ginsenoside from the fresh root of Panax ginseng, Molecules, 15, 2319, 10.3390/molecules15042319
Ryu, 1996, A genuine dammarane glycoside, (20E)-ginsenoside F4 from Korean red ginseng, Arch. Pharm. Res., 19, 335, 10.1007/BF02976251
Ryu, 1997, A dammarane glycoside from Korean red ginseng, Phytochemistry, 44, 931, 10.1016/S0031-9422(96)00661-9
Sanada, 1978, Comparative studies on the saponins of ginseng and related crude drugs (1), Shoyakugaku Zasshi, 32, 96
Sanada, 1978, Studies on the saponins of Ginseng. III. Structures of ginsenoside-Rb3 and 20-glucoginsenoside-Rf, Chem. Pharm. Bull., 26, 1694, 10.1248/cpb.26.1694
Sanada, 1974, Studies on the saponins of Ginseng. I. Structures of ginsenoside-Ro, -Rb1, -Rb2, -Rc, and Rd, Chem. Pharm. Bull., 22, 421, 10.1248/cpb.22.421
Sanada, 1974, Studies on the saponins of Ginseng. II. Structures of ginsenoside-Re, -Rf and-Rg2, Chem. Pharm. Bull., 22, 2407, 10.1248/cpb.22.2407
Shibata, 1963, Studies on the constituents of Japanese and Chinese crude drugs. XI. Panaxadiol, a sapogenin of Ginseng roots, Chem. Pharm. Bull., 11, 759, 10.1248/cpb.11.759
Shibata, 1966, Chemical studies on oriental plant drugs. XIV. Protopanaxadiol, a genuine sapogenin of Ginseng saponins, Chem. Pharm. Bull., 14, 595, 10.1248/cpb.14.595
Sun, 2005, Immunological-adjuvant saponins from the roots of Panax notoginseng, Chem. Biodivers., 2, 510, 10.1002/cbdv.200590032
Sun, 2007, Isolation and structure characterization of malonyl-notoginsenoside-R4 from the roots of Panax ginseng, Chem. J. Chin. Univ., 28, 1316
Tanaka, 1978, Dammarane saponins of leaves of Panax pseudo-ginseng subsp. himalaicus, Phytochemistry, 17, 1353, 10.1016/S0031-9422(00)94588-6
Tanaka, 1985, Study on saponins of rhizomes of Panax pseudo-ginseng subsp. himalaicus collected at Tzatogang and Pari-la, Bhutan-Himalaya, Chem. Pharm. Bull., 33, 2323, 10.1248/cpb.33.2323
Teng, 2002, Complete assignment of 1H and 13C NMR data for nine protopanaxatriol glycosides, Magn. Reson. Chem., 40, 483, 10.1002/mrc.1033
Teng, 2004, Hydrolytic reaction of plant extracts to generate molecular diversity: new dammarane glycosides from the mild acid hydrolysate of root saponins of Panax notoginseng, Helv. Chim. Acta, 87, 1270, 10.1002/hlca.200490116
Tran, 2001, Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity, J. Nat. Prod., 64, 456, 10.1021/np000393f
Tung, 2009, Two new dammarane-type saponins from the leaves of Panax ginseng, Chem. Pharm. Bull., 57, 1412, 10.1248/cpb.57.1412
Tung, 2010, Dammarane-type saponins from the flower buds of Panax ginseng and their effects on human leukemia cells, Bioorg. Med. Chem. Lett., 20, 309, 10.1016/j.bmcl.2009.10.110
Tung, 2010, Steamed ginseng-leaf components enhance cytotoxic effects on human leukemia HL-60 cells, Chem. Pharm. Bull., 58, 1111, 10.1248/cpb.58.1111
Tung, 2010, Dammarane-type saponins from the flower buds of Panax ginseng and their intracellular radical scavenging capacity, J. Agric. Food Chem., 58, 868, 10.1021/jf903334g
Tung, 2011, Oleanolic triterpene saponins from the roots of Panax bipinnatifidus, Chem. Pharm. Bull., 59, 1417, 10.1248/cpb.59.1417
Vincken, 2007, Saponins, classification and occurrence in the plant kingdom, Phytochemistry, 68, 275, 10.1016/j.phytochem.2006.10.008
Wan, 2010, 5,6-Didehydroginsenosides from the roots of Panax notoginseng, Molecules, 15, 8169, 10.3390/molecules15118169
Wang, 1989, Studies on saponins from the leaves of Panax japonicus var. bipinnatifidus (Seem.) Wu et Feng, Acta Pharm. Sin., 24, 593
Wang, 1989, Further study on dammarane saponin of leaves of Panax japonicus var. major collected in Quinling Mountains China, Acta Pharm. Sin., 24, 633
Wang, 1998, A new saponin from the leaves and stems of Panax quinquefolium L. collected in Canada, J. Asian Nat. Prod. Res., 1, 93, 10.1080/10286029808039849
Wang, 2001, Quinquenoside L9 from leaves and stems of Panax quinquefolium L., J. Asian Nat. Prod. Res., 3, 293, 10.1080/10286020108040369
Wang, 2001, Triterpenoid saponins from leaves and stems of Panax quinquefolium L., J. Asian Nat. Prod. Res., 3, 123, 10.1080/10286020108041379
Wang, 2004, Isoginsenoside-Rh3, a new triterpenoid saponin from the fruits of Panax ginseng C.A. Meyer, J. Asian Nat. Prod. Res., 6, 289, 10.1080/10286020310001595980
Wang, 2008, A new compound with cytotoxic activities from the leaves of Panax ginseng C.A. Meyer, Chin. Chem. Lett., 19, 837, 10.1016/j.cclet.2008.05.017
Wang, 2008, Two new dammarane-type bisdesmosides from the fruit pedicels of Panax notoginseng, Helv. Chim. Acta, 91, 60, 10.1002/hlca.200890013
Wang, 2009, Dammarane-type triterpene saponins from the flowers of Panax notoginseng, Molecules, 14, 2087, 10.3390/molecules14062087
Wei, 1992, Studies on the saponins in the fruit pedicels of Panax notoginseng (Burk.) F. H. Chen, Chin. J. Chin. Mater. Med., 17, 611
Yahara, 1976, Saponins of the leaves of Panax ginseng C.A. Meyer, Chem. Pharm. Bull., 24, 2204, 10.1248/cpb.24.2204
Yahara, 1977, New dammarane type saponins of leaves of Panax japonicus C.A. Meyer. (1). Chikusetsusaponins-L5, -L9a and –L10, Chem. Pharm. Bull., 25, 2041, 10.1248/cpb.25.2041
Yahara, 1979, Further study on dammarane-type saponins of roots, leaves, flower-buds, and fruits of Panax ginseng C.A. Meyer, Chem. Pharm. Bull., 27, 88, 10.1248/cpb.27.88
Yang, 1983, Dammarane saponins of leaves and seeds of Panax notoginseng, Phytochemistry, 22, 1473, 10.1016/S0031-9422(00)84039-X
Yoshikawa, 1997, Bioactive saponins and glycosides. VIII. Notoginseng (1): new dammarane-type triterpene oligoglycosides, notoginsenosides-A, -B, -C, and –D, from the dried root of Panax notoginseng (Burk.) F. H. Chen, Chem. Pharm. Bull., 45, 1039, 10.1248/cpb.45.1039
Yoshikawa, 1998, Bioactive saponins and glycosides. XI. Structures of new dammarane-type triterpene oligoglycosides, quinquenosides I, II, III, IV, and V, from American ginseng, the roots of Panax quinquefolium L., Chem. Pharm. Bull., 46, 647, 10.1248/cpb.46.647
Yoshikawa, 2001, Bioactive saponins and glycosides. XIX. Notoginseng (3): immunological adjuvant activity of notoginsenosides and related saponins: structures of notoginsenosides-L, -M, and -N from the roots of Panax notoginseng (Burk.) F. H. Chen, Chem. Pharm. Bull., 49, 1452, 10.1248/cpb.49.1452
Yoshikawa, 2003, Structures of new dammarane-type triterpene saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal Ginseng saponins, J. Nat. Prod., 66, 922, 10.1021/np030015l
Yoshikawa, 2007, Medicinal flowers. XI. Structures of new dammarane-type triterpene diglycosides with hydroperoxide group from flower buds of Panax ginseng, Chem. Pharm. Bull., 55, 571, 10.1248/cpb.55.571
Yoshikawa, 2007, Medicinal flowers. XVI. New dammarane-type triterpene tetraglycosides and gastroprotective principles from flower buds of Panax ginseng, Chem. Pharm. Bull., 55, 1034, 10.1248/cpb.55.1034
Yoshizaki, 2012, New triterpenoid saponins from fruits specimens of Panax japonicus collected in Kumamoto and Miyazaki Prefectures (1), Chem. Pharm. Bull., 60, 354, 10.1248/cpb.60.354
Yoshizaki, 2012, New triterpenoid saponins from leaves of Panax japonicus (3). Saponins of the specimens collected in Miyazaki prefecture, Nat. Prod. Commun., 7, 491
Yoshizaki, 2012, New triterpenoid saponins from fruit specimens of Panax japonicus collected in Toyama prefecture and Hokkaido, Chem. Pharm. Bull., 60, 728, 10.1248/cpb.60.728
Yun, 2001, Anticarcinogenic effect of Panax ginseng C.A. Meyer and identification of active compounds, J. Korean Med. Sci., 16, S6, 10.3346/jkms.2001.16.S.S6
Zhang, 1989, A new minor saponin from the leaves of Panax ginseng C.A. Meyer, Acta Pharm. Sin., 24, 877
Zhang, 2002, Polyacetyleneginsenoside-Ro, a novel triterpene saponin from Panax ginseng, Tetrahedron Lett., 43, 973, 10.1016/S0040-4039(01)02310-3
Zhao, 1996, Minor dammarane saponins from Panax notoginseng, Phytochemistry, 41, 1419, 10.1016/0031-9422(95)00785-7
Zhao, 2010, A new triterpene saponin from Panax japonicus C.A. Meyer var major (Burk.) C.Y. Wu et K.M. Feng, Chin. Chem. Lett., 21, 1216, 10.1016/j.cclet.2010.06.010
Zhao, 2011, Novel dammarane-type saponins from Panax ginseng berry and their biological activities, Bioorg. Med. Chem. Lett., 21, 1027, 10.1016/j.bmcl.2010.12.035
Zhou, 1981, Dammarane-saponins of Sanchi-ginseng, roots of Panax notoginseng (Burk) F. H. Chen (Araliaceae). Structures of new saponins notoginsenoside R1 and notoginsenoside R2, and identification of ginsenosides Rg2 and ginsenoside Rh1, Chem. Pharm. Bull., 29, 2844, 10.1248/cpb.29.2844
Zhou, 2011, New dammarane-type saponins from the rhizomes of Panax japonicus, Helv. Chim. Acta, 94, 2010, 10.1002/hlca.201100085
Zhu, 2011, Protopanaxatriol-type ginsenosides from the root of Panax ginseng, J. Agric. Food Chem., 59, 200, 10.1021/jf1037932
Zhu, 2011, Acylated protopanaxadiol-type ginsenosides from the root of Panax ginseng, Chem. Biodivers., 8, 1853, 10.1002/cbdv.201000196
Zou, 2002, Dammarane-type saponins from Panax japonicus and their neurite outgrowth activity in SK-N-SH cells, J. Nat. Prod., 65, 1288, 10.1021/np0201117