Role of mitochondrial DNA in toxic responses to oxidative stress

DNA Repair - Tập 5 Số 2 - Trang 145-152 - 2006
Bennett Van Houten1, Victoria Woshner2, Janine H. Santos1
1Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, P.O. Box 12233, Research Triangle Park, NC 27709, USA
2Wildlife Health Consultants, Hillsborough, NC 27278, USA

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Garrido, 2004, Life's smile, death's grin: vital functions of apoptosis-executing proteins, Curr. Opin. Cell Biol., 16, 639, 10.1016/j.ceb.2004.09.008

Boveris, 1972, The cellular production of hydrogen peroxide, Biochem. J., 128, 617, 10.1042/bj1280617

Inoue, 2003, Mitochondrial generation of reactive oxygen species and its role in aerobic life, Curr. Med. Chem., 10, 2495, 10.2174/0929867033456477

Chomyn, 2003, mtDNA mutations in aging and apoptosis, Biochem. Biophys. Res. Commun., 304, 519, 10.1016/S0006-291X(03)00625-9

Wallace, 2003, mtDNA variation, climatic adaptation, degenerative diseases, and longevity, Cold Spring Harb. Symp. Quant. Biol., 68, 479, 10.1101/sqb.2003.68.471

McKenzie, 2004, Mitochondrial disease: mutations and mechanisms, Neurochem. Res., 29, 589, 10.1023/B:NERE.0000014829.42364.dd

Aruoma, 1991, Oxygen free radicals and human diseases, J. R. Soc. Health, 111, 172, 10.1177/146642409111100506

Shukla, 2003, Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis, Am. J. Physiol. Lung Cell. Mol. Physiol., 285, L1018, 10.1152/ajplung.00038.2003

Panduri, 2004, Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis, Am. J. Physiol. Lung Cell. Mol. Physiol., 286, L1220, 10.1152/ajplung.00371.2003

Cossarizza, 2002, HIV infection: the first decade, J. Biol. Regul. Homeost. Agents, 16, 18

Penta, 2001, Mitochondrial DNA in human malignancy, Mutat. Res., 488, 119, 10.1016/S1383-5742(01)00053-9

Van Houten, 1997, The role of the host response in oxidative damage and malignant transformation, Mucosal Immunol. Update, 5, 64

Enns, 2003, The contribution of mitochondria to common disorders, Mol. Genet. Metab., 80, 11, 10.1016/j.ymgme.2003.08.009

Choy, 2001, Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis, J. Mol. Cell Cardiol., 33, 1673, 10.1006/jmcc.2001.1419

Sorescu, 2002, Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure, Congest. Heart Fail, 8, 132, 10.1111/j.1527-5299.2002.00717.x

Tsutsui, 2001, Oxidative stress in heart failure: the role of mitochondria, Intern. Med., 40, 1177, 10.2169/internalmedicine.40.1177

Yorek, 2003, The role of oxidative stress in diabetic vascular and neural disease, Free Radic. Res., 37, 471, 10.1080/1071576031000083161

Duchen, 2004, Roles of mitochondria in health and disease, Diabetes, 53, S96, 10.2337/diabetes.53.2007.S96

Toledo-Pereyra, 2004, Reactive oxygen species and molecular biology of ischemia/reperfusion, Ann. Transplant., 9, 81

Rouault, 2003, Hepatic iron overload in alcoholic liver disease: why does it occur and what is its role in pathogenesis?, Alcohol, 30, 103, 10.1016/S0741-8329(03)00102-2

Loguercio, 2003, Oxidative stress in viral and alcoholic hepatitis, Free Radic. Biol. Med., 34, 1, 10.1016/S0891-5849(02)01167-X

Bailey, 2002, Contribution of mitochondria to oxidative stress associated with alcoholic liver disease, Free Radic. Biol. Med., 32, 11, 10.1016/S0891-5849(01)00769-9

Fleming, 2002, Mechanisms of iron accumulation in hereditary hemochormatosis, Annu. Rev. Physol., 64, 663, 10.1146/annurev.physiol.64.081501.155838

Andersen, 2004, Oxidative stress in neurodegeneration: cause or consequence?, Nat. Med., 10, S18, 10.1038/nrn1434

Emerit, 2004, Neurodegenerative diseases and oxidative stress, Biomed. Pharmacother., 58, 39, 10.1016/j.biopha.2003.11.004

Vina, 2004, Molecular bases of the treatment of Alzheimer's disease with antioxidants: prevention of oxidative stress, Mol. Aspects Med., 25, 117, 10.1016/j.mam.2004.02.013

Canevari, 2004, Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress, Neurochem. Res., 29, 637, 10.1023/B:NERE.0000014834.06405.af

Rossi, 2004, Mitochondrial dysfunction in neurodegenerative diseases associated with copper imbalance, Neurochem. Res., 29, 493, 10.1023/B:NERE.0000014820.99232.8a

Cluskey, 2001, Mechanisms of neurodegeneration in amyotrophic lateral sclerosis, Mol. Pathol., 54, 386

Alper, 2003, Friedreich's ataxia, Pediatr. Neurol., 28, 335, 10.1016/S0887-8994(03)00004-3

Richardson, 2003, Friedreich's ataxia: iron chelators that target the mitochondrion as a therapeutic strategy?, Expert Opin. Invest. Drugs, 12, 235, 10.1517/13543784.12.2.235

Puccio, 2002, Friedreich ataxia: a paradigm for mitochondrial diseases, Curr. Opin. Genet. Dev., 12, 272, 10.1016/S0959-437X(02)00298-8

Calabrese, 2001, Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity, Neurochem. Res., 26, 739, 10.1023/A:1010955807739

Trushina, 2004, Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro, Mol. Cell Biol., 24, 8195, 10.1128/MCB.24.18.8195-8209.2004

Browne, 1999, Oxidative stress in Huntington's disease, Brain Pathol., 9, 147, 10.1111/j.1750-3639.1999.tb00216.x

Beal, 1998, Mitochondrial dysfunction in neurodegenerative diseases, Biochim. Biophys. Acta, 1366, 211, 10.1016/S0005-2728(98)00114-5

Tretter, 2004, Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease, Neurochem. Res., 29, 569, 10.1023/B:NERE.0000014827.94562.4b

Beal, 2003, Mitochondria, oxidative damage, and inflammation in Parkinson's disease, Ann. N. Y. Acad. Sci., 991, 120, 10.1111/j.1749-6632.2003.tb07470.x

Orth, 2002, Mitochondrial involvement in Parkinson's disease, Neurochem. Int., 40, 533, 10.1016/S0197-0186(01)00124-3

Richter, 1988, Normal oxidative damage to mitochondrial and nuclear DNA is extensive, Proc. Natl. Acad. Sci. U.S.A., 85, 6465, 10.1073/pnas.85.17.6465

Helbock, 1998, DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine, Proc. Natl. Acad. Sci. U.S.A., 95, 288, 10.1073/pnas.95.1.288

Yakes, 1997, Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress, Proc. Natl. Acad. Sci. U.S.A., 94, 514, 10.1073/pnas.94.2.514

Salazar, 1997, Preferential mitochondrial DNA injury caused by glucose oxidase as a steady generator for hydrogen peroxide in human fibroblasts, Mutat. Res., 385, 139, 10.1016/S0921-8777(97)00047-5

Santos, 2002, Measurement of oxidative damage and repair in mitochondria using quantitative PCR, Methods Mol. Biol., 197, 159

Clayton, 1974, The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria, Proc. Natl. Acad. Sci. U.S.A., 71, 2777, 10.1073/pnas.71.7.2777

Alexeyev, 2004, Mitochondrial DNA and aging, Clin. Sci. (Lond.), 107, 355, 10.1042/CS20040148

Bogenhagen, 2001, Enzymology of mitochondrial base excision repair, Prog. Nucleic Acid Res. Mol. Biol., 68, 257, 10.1016/S0079-6603(01)68105-4

Bohr, 2002, Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells, Free Radic. Biol. Med., 32, 804, 10.1016/S0891-5849(02)00787-6

Dianov, 2001, Base excision repair in nuclear and mitochondrial DNA, Prog. Nucleic Acid Res. Mol. Biol., 68, 285, 10.1016/S0079-6603(01)68107-8

Ledoux, 2001, Base excision repair of mitochondrial DNA damage in mammalian cells, Prog. Nucleic Acid Res. Mol. Biol., 68, 273, 10.1016/S0079-6603(01)68106-6

Mandavilli, 2002, Mitochondrial DNA repair and aging, Mutat. Res., 509, 127, 10.1016/S0027-5107(02)00220-8

Sawyer, 1999, Repair of DNA damage in mitochondria, Mutat. Res., 434, 161, 10.1016/S0921-8777(99)00027-0

Pettepher, 1991, Repair of alkali-labile sites within the mitochondrial DNA of RINr 38 cells after exposure to the nitrosourea streptozotocin, J. Biol. Chem., 266, 3113, 10.1016/S0021-9258(18)49961-9

Driggers, 1993, Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells, J. Biol. Chem., 268, 22042, 10.1016/S0021-9258(20)80645-0

Chen, 1998, Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines, Nucleic Acids Res., 26, 2001, 10.1093/nar/26.8.2001

Ballinger, 2000, Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells, Circ. Res., 86, 960, 10.1161/01.RES.86.9.960

Deng, 1999, Bcl-2 facilitates recovery from DNA damage after oxidative stress, Exp. Neurol., 159, 309, 10.1006/exnr.1999.7145

Mandavilli, 2005, Bcl-2 protects against 3-nitropropionic acid, a complex II inhibitor induced ROS and mitochondrial DNA damage in PC12 cells, Mol. Brain Res., 133, 215, 10.1016/j.molbrainres.2004.10.033

Santos, 2003, Cell-sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death, J. Biol. Chem., 278, 1728, 10.1074/jbc.M208752200

Cardoso, 2001, Functional mitochondria are required for amyloid β-mediated neurotoxicity, FASEB J., 15, 1439, 10.1096/fj.00-0561fje

Cardoso, 2002, Induction of cytochrome c-mediated apoptosis by amyloid β 25–35 requires functional mitochondria, Brain Res., 931, 117, 10.1016/S0006-8993(02)02256-4

Cardoso, 2004, Apoptotic cell death induced by hydrogen peroxide in NT2 parental and mitochondrial DNA depleted cells, Neurochem Int., 45, 693, 10.1016/j.neuint.2004.03.003

Dobson, 2000, Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria, J. Biol. Chem., 275, 37518, 10.1074/jbc.M000831200

Dobson, 2002, Enhanced mtDNA repair capacity protects pulmonary artery endothelial cells from oxidant-mediated death, Am. J. Physiol. Lung Cell. Mol. Physiol., 283, L205, 10.1152/ajplung.00443.2001

Druzhyna, 2003, Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress, Glia, 42, 370, 10.1002/glia.10230

Shokolenko, 2003, The expression of Exonuclease III from E. coli in mitochondria of breast cancer cells diminishes mitochondrial DNA repair capacity and cell survival after oxidative stress, DNA Repair (Amst.), 2, 471, 10.1016/S1568-7864(03)00019-3

Fishel, 2003, Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing, Cancer Res., 63, 608

Rachek, 2004, Endonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress, Nucleic Acids Res., 32, 3240, 10.1093/nar/gkh648

Ruchko, 2005, Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells, Am. J. Physiol. Lung Cell. Mol. Physiol., 288, L530, 10.1152/ajplung.00255.2004

Grishko, 2005, Contribution of mitochondrial DNA repair to cell resistance from oxidative stress, J. Biol. Chem., 280, 8901, 10.1074/jbc.M413022200

Green, 2004, The pathophysiology of mitochondrial cell death, Science, 305, 626, 10.1126/science.1099320

Shen, 2003, Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts, DNA Repair, 2, 673, 10.1016/S1568-7864(03)00006-5

Szczesny, 2004, Age-dependent modulation of DNA repair enzymes by covalent modification and subcellular distribution, Mech. Ageing Dev., 125, 755, 10.1016/j.mad.2004.07.005

Szczesny, 2003, Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases, Proc. Natl. Acad. Sci. U.S.A., 100, 10670, 10.1073/pnas.1932854100

Trifunovic, 2004, Premature ageing in mice expressing defective mitochondrial DNA polymerase, Nature, 429, 417, 10.1038/nature02517