Role of Palliative Care in the Outpatient Management of the Chronic Heart Failure Patient

Springer Science and Business Media LLC - Tập 16 - Trang 220-228 - 2019
Sarah Chuzi1, Esther S. Pak2, Akshay S. Desai3,4, Kristen G. Schaefer4,5,6, Haider J. Warraich3,4,7
1Division of Cardiology, Department of Medicine, Northwestern University at Feinberg School of Medicine, Chicago, USA
2Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, USA
3Center for Advanced Heart Disease, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, USA
4Harvard Medical School, Boston, USA;
5Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, Boston, USA
6Division of Palliative Medicine, Brigham and Women’s Hospital, Boston, USA
7Cardiology Section, Department of Medicine, Boston VA Healthcare System, Boston, USA

Tóm tắt

Patients with heart failure (HF) have an increased symptom burden and complex psychosocial and decision-making needs that necessitate the integration of palliative care. However, in the current era, palliative care is frequently evoked for these patients only at the end-of-life or in the inpatient setting; rarely is palliative care proactively utilized in outpatients with HF. The purpose of this review is to evaluate the current state of palliative care and heart failure and to provide a roadmap for the integration of palliative care into outpatient HF care. Recent studies, including PAL-HF, CASA, and SWAP-HF, have demonstrated that structured palliative care interventions may improve quality of life, depression, anxiety, understanding of prognosis, and well-being in HF. HF is associated with high mortality risk, significant symptom burden, and impaired quality of life. Palliative care can meet many of these needs; however, in the current era, palliative care consultations in HF occur late in the disease course and too often in the inpatient setting. Primary palliative care should be provided to all outpatients with heart failure based on their needs, with referral to secondary palliative care provided based on certain triggers and milestones.

Tài liệu tham khảo

Benjamin EJ, Muntner P, Alonso A, et al. Heart disease and stroke statistics—2019 update: a report from the American Heart Association. Circulation. 2019;139:e56–e528.

Curtis LH, Greiner MA, Hammill BG, et al. Early and long-term outcomes of heart failure in elderly persons, 2001-2005. JAMA Intern Med. 2008;168:2481–8.

Sepúlveda C, Marlin A, Yoshida T, Ullrich A. Palliative Care: The World Health Organization’s global perspective. J Pain Symptom Manag. 2002;24:91–6.

Allen LA, Stevenson LW, Grady KL, et al. Decision making in advanced heart failure: a scientific statement from the American Heart Association. Circulation. 2012;125:1928–52.

Braun Lynne T, Grady Kathleen L, Kutner Jean S, et al. Palliative care and cardiovascular disease and stroke: a policy statement from the American Heart Association/American Stroke Association. Circulation. 2016;134:e198–225.

Warraich HJ, Wolf SP, Mentz RJ, Rogers JG, Samsa G, Kamal AH. Characteristics and trends among patients with cardiovascular disease referred to palliative carecharacteristics and trends among patients with cardiovascular disease referred to palliative carecharacteristics and trends among patients with cardiovascular disease referred to palliative care. JAMA Netw Open. 2019;2:e192375–5.

Weitzen S, Teno JM, Fennell M, Mor V. Factors associated with site of death: a national study of where people die. Med Care. 2003;41:323–35.

Services CfMaM. Proposed decision memo for ventricular assist devices for bridge-to-transplant and destination therapy (CAG-00432R).

Nakagawa S, Garan AR. Hospice use and palliative care for patients with heart failure: never say never in medicine, but it is never too early to start the conversationpalliative care and hospice for patients with heart failure research. JAMA Cardiol. 2018;3:926–8.

• Warraich HJ, Xu H, DeVore AD, et al. Trends in hospice discharge and relative outcomes among medicare patients in the get with the guidelines–Heart Failure Registry Trends in Hospice Discharge and Outcomes Among Medicare Patients in the GWTG-HF Registry Trends in Hospice Discharge and Outcomes Among Medicare Patients in the GWTG-HF Registry. JAMA Cardiol. 2018;3:917–26 This registry review of Medicare-linked claims data of HF patients showed infrequent hospice utilization among HF patients. When referred, patients were often referred too late with brief hospice enrollment.

Rutledge T, Reis VA, Linke SE, Greenberg BH, Mills PJ. Depression in heart failure: a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol. 2006;48:1527–37.

Allen LA, Matlock DD, Shetterly SM, et al. Use of risk models to predict death in the next year among individual ambulatory patients with heart failurepredicting death among ambulatory patients with heart failurepredicting death among ambulatory patients with heart failure. JAMA Cardiol. 2017;2:435–41.

Bidwell JT, Lyons KS, Lee CS. Caregiver well-being and patient outcomes in heart failure: a meta-analysis. J Cardiovasc Nurs. 2017;32:372–82.

Dunbar Sandra B, Khavjou Olga A, Bakas T, et al. Projected costs of informal caregiving for cardiovascular disease: 2015 to 2035: A Policy Statement From the American Heart Association. Circulation. 2018;137:e558–77.

•• Rogers JG, Patel CB, Mentz RJ, et al. Palliative care in heart failure. The PAL-HF Randomized, Controlled Clinical Trial. J Am Coll Cardiol. 2017;70:331–41 The PAL-HF studied and demonstrated that palliative care involvement in patients in addition to usual care led to improvement in HF-related quality of life, depression, and spiritual wellbeing.

•• O’Donnell AE, Schaefer KG, Stevenson LW, et al. Social worker–Aided Palliative Care Intervention in High-risk Patients With Heart Failure (SWAP-HF): a pilot randomized clinical trial. JAMA Cardiol. 2018;3:516–9 This study showed that intervention led by social work resulted in increased documentation of patient preferences and increased concordance between physician and patient assessment of prognosis.

Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606–13.

•• Bekelman DB, Allen LA, et al. Effect of a collaborative care intervention vs usual care on health status of patients with chronic heart failure: the CASA Randomized Clinical Trial. JAMA Intern Med. 2018;178(4):511–9 This study showed that though focused symptom and psychosocial intervention did not result in difference in health status, secondary outcomes including depression and fatigue improved.