Role of Mendelian genes in “sporadic” Parkinson's disease

Lesage, 2009, Parkinson's disease: from monogenic forms to genetic susceptibility factors, Hum Mol Genet, 18, R48, 10.1093/hmg/ddp012

Chartier-Harlin, 2011, Translation Initiator EIF4G1 Mutations in Familial Parkinson Disease, Am J Hum Genet, 89, 398, 10.1016/j.ajhg.2011.08.009

Vilarino-Guell, 2011, VPS35 mutations in Parkinson disease, Am J Hum Genet, 89, 162, 10.1016/j.ajhg.2011.06.001

Zimprich, 2011, A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease, Am J Hum Genet, 89, 168, 10.1016/j.ajhg.2011.06.008

Polymeropoulos, 1997, Mutation in the alpha-synuclein gene identified in families with Parkinson's disease, Science, 276, 2045, 10.1126/science.276.5321.2045

Singleton, 2003, alpha-Synuclein locus triplication causes Parkinson's disease, Science, 302, 841, 10.1126/science.1090278

Bardien, 2011, Genetic characteristics of leucine-rich repeat kinase 2 (LRRK2) associated Parkinson's disease, Parkinsonism Relat Disord, 17, 501, 10.1016/j.parkreldis.2010.11.008

Nuytemans, 2010, Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update, Hum Mutat, 31, 763, 10.1002/humu.21277

Lohmann, 2003, How much phenotypic variation can be attributed to parkin genotype?, Ann Neurol, 54, 176, 10.1002/ana.10613

Klein, 2007, Deciphering the role of heterozygous mutations in genes associated with parkinsonism, Lancet Neurol, 6, 652, 10.1016/S1474-4422(07)70174-6

Kay, 2010, A comprehensive analysis of deletions, multiplications, and copy number variations in PARK2, Neurology, 75, 1189, 10.1212/WNL.0b013e3181f4d832

Marongiu, 2008, PINK1 heterozygous rare variants: prevalence, significance and phenotypic spectrum, Hum Mutat, 29, 565, 10.1002/humu.20719

Choi, 2006, Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases, J Biol Chem, 281, 10816, 10.1074/jbc.M509079200

Tan, 2007, The role of common genetic risk variants in Parkinson disease, Clinical genetics, 72, 387, 10.1111/j.1399-0004.2007.00890.x

Sidransky, 2009, Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease, N Engl J Med, 361, 1651, 10.1056/NEJMoa0901281

Lesage, 2011, Large-scale screening of the Gaucher's disease-related glucocerebrosidase gene in Europeans with Parkinson's disease, Hum Mol Genet, 20, 202, 10.1093/hmg/ddq454

Satake, 2009, Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease, Nat genet, 41, 1303, 10.1038/ng.485

Saad, 2011, Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population, Hum Mol Genet, 20, 615, 10.1093/hmg/ddq497

Hamza, 2010, Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease, Nat genet, 42, 781, 10.1038/ng.642

International Parkinson's Disease Genomics Consortium (IPDGC), 2011, A two-stage meta-analysis identifies several new loci for Parkinson's disease, PLoS Genet, 7, e1002142, 10.1371/journal.pgen.1002142