Review: The Pharmacology of Dobutamine

Akhtar, 1975, Hemodynamic effect of dobutamine in patients with severe heart failure, Am J Cardiol, 36, 202, 10.1016/0002-9149(75)90526-3

Loeb, 1975, Hemodynamic effects of dobutamine in man, Circ Shock, 2, 29

Jewitt, 1974, Clinical cardiovascular pharmacology of dobutamine, Lancet, 2, 363, 10.1016/S0140-6736(74)91754-1

Liang, 1979, Dobutamine infusion in conscious dogs with and without autonomic nervous system inhibition: Effects of systemic hemodynamics, regional blood flows and cardiac metabolism, J Pharmacol Exp Ther, 211, 698

Ruffolo, 1984, Interaction of the novel inotropic agent, ASL-7022, with a- and β-adrenoceptors in the cardiovascular system of the pithed rat: Comparison with dobutamine and dopamine, J Pharmacol ExpTher, 229, 364

Leier, 1977, The cardiovascular effects of the continuous infusion of dobutamine in patients with severe cardiac failure, Circulation, 56, 468, 10.1161/01.CIR.56.3.468

Sonnenblick, 1979, Dobutamine: A new synthetic cardioactive sympathetic amine, N Engl J Med, 300, 17, 10.1056/NEJM197901043000105

Leier, 1977, Comparative systemic regional hemodynamic effects of dopamine and dobutamine in patients with cardiomyopathic failure, Circulation, 58, 466, 10.1161/01.CIR.58.3.466

Goldberg, 1977, Newer catecholamines for treatment of heart failure and shock: An update on dopamine and a first look at dobutamine, Prog Cardiovasc Dis, 19, 327, 10.1016/0033-0620(77)90007-X

Loeb, 1971, Acute hemodynamic effects of dobutamine and isoproterenol in patients with low output cardiac failure, Circ Shock, 3, 55

Tuttle, 1975, Dobutamine: Development of a new catecholamine to selectively increase cardiac contractility, Circ Res, 36, 185, 10.1161/01.RES.36.1.185

Loeb, 1977, Superiority of dobutamine over dopamine for augmentation of cardiac output in patients with chronic low output cardiac failure, Circulation, 55, 375, 10.1161/01.CIR.55.2.375

Leier, 1983, Dobutamine, Ann Intern Med, 99, 490, 10.7326/0003-4819-99-4-490

Guiha, 1974, Treatment of refractory heart failure with infusion of nitro-prusside, N Engl J Med, 291, 587, 10.1056/NEJM197409192911201

Chatterjee, 1977, The role of vasodilator therapy in heart failure, ProgrCardiovasc, 19, 301

Mikulic, 1977, Comparative hemodynamic effects of inotropic and vasodilator drugs in severe heart failure, Circulation, 56, 528, 10.1161/01.CIR.56.4.528

Berkowitz, 1977, Comparative responses to dobutamine and nitroprusside in patients with chronic low output cardiac failure, Circulation, 56, 918, 10.1161/01.CIR.56.6.918

Ruffolo, 1983, Drug, neurotransmitter and hormone receptors in the regulation of the cardiovascular system, K1

Ruffolo, 1984, Interaction of three inotropic agents, ASL-7022, dobutamine and dopamine, with a- and β-adrenoceptors in vitro, Naunyn Schmeidebergs Arch Pharmacol, 326, 317, 10.1007/BF00501436

Ruffolo, 1983, Vascular effects of the stereoisomers of dobutamine, J Pharmacol Exp Ther, 224, 46

Ruffolo, 1985, Systemic hemodynamic effects of dopamine, (+)-dobutamine and the (+)- and (-)-enanti- omers of dobutamine in anesthetized normotensive rats, Eur J Pharmacol, 109, 173, 10.1016/0014-2999(85)90418-2

Ruffolo, 1981, Murphy PJ: α- and β-adrenergic effects of the stereoisomers of dobutamine, J Pharmacol Exp Ther, 219, 447

Murphy, 1976, Disposition of dobutamine in the dog, J Pharmacol ExpTher, 119, 423

Ruffolo, 1985, Interactions of the enantiomers of 3-O-methyldobutamine with α- and β-adrenoceptors in vitro, Naunyn Schmeidebergs Arch Pharmacol, 329, 244, 10.1007/BF00501875

Robie, 1974, In vivo analysis of adrenergic receptor activity of dobutamine, Circ Res, 34, 663, 10.1161/01.RES.34.5.663

Kenakin, 1981, An in vitro quantitative analysis of the α-adrenoceptor partial agonist activity of dobutamine and its relevance to inotropic selectivity, J Pharmacol ExpTher, 216, 210

Maccarrone, 1984, Raper C: β-Adrenoceptor selectivity of dobutamine: In vivo and in vitro studies, J Cardiovasc Pharmacol, 6, 132, 10.1097/00005344-198401000-00021

Schumann, 1979, Demonstration of α-adrenoceptor in the rabbit heart by 3H-dihydroergocryptine binding, Naunyn-Schmeideberg’s Arch Pharmacol, 308, 191, 10.1007/BF00501382

Schumann, 1976, Endoh M: α-Adrenoceptors in the ventricular myocardium: Clonidine, naphazoline and methoxamine as partial α-agonists exerting a competitive dualism in action to phenylephrine, Eur J Pharmacol, 36, 413, 10.1016/0014-2999(76)90095-9

Ruffolo, 1985, Inotropic selectivity of dobutamine enantiomers in pithed rat, J Pharmacol Exp Ther, 235, 344

Ruffolo, 1984, On the mechanism of action of dobutamine, Ann Intern Med, 100, 313, 10.7326/0003-4819-100-2-313