Resistance of germfree rats to indomethacin-induced intestinal lesions

Prostaglandins - Tập 14 Số 2 - Trang 333-341 - 1977
André Robert1, Tomoaki Asano2
1Department of Experimental Biology The Upjohn Company, Kalamazoo, MI 49001 USA
2Department of Microbiology, University of Notre Dame, Notre Dame, Indiana 46556 USA

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Tài liệu tham khảo

Kent, 1969, Small intestinal ulcers and intestinal flora in rats given indomethacin, Am. J. Pathol., 54, 237

Wax, 1970, Relationship of the enterohepatic cycle to ulcerogenesis in the rat small bowel with flufenamic acid, Gastroenterology, 58, 772, 10.1016/S0016-5085(70)80149-4

Robert, 1974, Effects of prostaglandins on the stomach and the intestine, Prostaglandins, 6, 523, 10.1016/S0090-6980(74)80062-6

Robert, 1975, An intestinal disease produced experimentally by a prostaglandin deficiency, Gastroenterology, 69, 1045, 10.1016/S0016-5085(19)32433-3

Wagner, 1959, Determination of germfree status, Ann. N.Y. Acad. Sci., 78, 89, 10.1111/j.1749-6632.1959.tb53097.x

Vane, 1971, Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs, Nature New Biol., 231, 232, 10.1038/newbio231232a0

Kellogg, 1973, Bile acid metabolism in gnotobiotic animals, 283

Kellogg, 1969, Fecal neutral steroids and bile acids from germfree rats, J. Lipid Res., 10, 495, 10.1016/S0022-2275(20)43040-8

Brodie, 1970, Indomethacin-induced intestinal lesions in the rat, Toxicol. Appl. Pharmacol., 17, 615, 10.1016/0041-008X(70)90036-0