Regulation of the p27Kip1 tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

EMBO Journal - Tập 26 Số 15 - Trang 3699-3708 - 2007
Carlos le Sage1, Remco Nagel1, David A. Egan2, Mariëtte Schrier1, Elly Mesman1, Annunziato Mangiola3, C. Anile3, Giulio Maira3, Neri Mercatelli4, Silvia Anna Ciafré4, Maria Giulia Farace4, Reuven Agami1
1Division of Tumor Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
2Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands
3Department of Neurosurgery, Catholic University of the Sacred Heart, Rome, Italy
4Department of Experimental Medicine and Biochemical Sciences, University of Rome “Tor Vergata” Rome, Italy

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