Reactive Oxygen Species in TNFα-Induced Signaling and Cell Death
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Akimaru, 1992, Role of tyrosyl phosphorylation in neutrophil priming by tumor necrosis factor-alpha and granulocyte colony stimulating factor, Arch. Biochem. Biophys., 298, 703, 10.1016/0003-9861(92)90469-D
Andrieu-Abadie, 2001, Ceramide in apoptosis signaling: relationship with oxidative stress, Free Radic. Biol. Med., 31, 717, 10.1016/S0891-5849(01)00655-4
Anilkumar, 2008, Nox4 and nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation, Arterioscler. Thromb. Vasc. Biol., 28, 1347, 10.1161/ATVBAHA.108.164277
Artal-Sanz, 2006, Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans, J. Cell Biol., 173, 231, 10.1083/jcb.200511103
Banfi, 2003, Two novel proteins activate superoxide generation by the NADPH oxidase NOX1, J. Biol. Chem., 278, 3510, 10.1074/jbc.C200613200
Baud, 1999, Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain, Genes Dev., 13, 1297, 10.1101/gad.13.10.1297
Beinke, 2004, Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology, Biochem. J., 382, 393, 10.1042/BJ20040544
Bertrand, 2008, cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination, Mol. Cell, 30, 689, 10.1016/j.molcel.2008.05.014
Blonska, 2005, TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha). receptor 1 complex in a receptor-interacting protein (RIP).-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation, J. Biol. Chem., 280, 43056, 10.1074/jbc.M507807200
Bogoyevitch, 2006, Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases, Microbiol. Mol. Biol. Rev., 70, 1061, 10.1128/MMBR.00025-06
Bonizzi, 2004, The two NF-kappaB activation pathways and their role in innate and adaptive immunity, Trends Immunol., 25, 280, 10.1016/j.it.2004.03.008
Boveris, 1973, The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen, Biochem. J., 134, 707, 10.1042/bj1340707
Boveris, 1975, Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration, FEBS Lett., 54, 311, 10.1016/0014-5793(75)80928-8
Boya, 2008, Lysosomal membrane permeabilization in cell death, Oncogene, 27, 6434, 10.1038/onc.2008.310
Brancho, 2005, Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades, Mol. Cell. Biol., 25, 3670, 10.1128/MCB.25.9.3670-3681.2005
Brown, 2009, Nox proteins in signal transduction, Free Radic. Biol. Med., 47, 1239, 10.1016/j.freeradbiomed.2009.07.023
Byun, 2008, Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase, Exp. Mol. Med., 40, 186, 10.3858/emm.2008.40.2.186
Cardone, 1997, The regulation of anoikis: MEKK-1 activation requires cleavage by caspases, Cell, 90, 315, 10.1016/S0092-8674(00)80339-6
Chang, 2006, The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover, Cell, 124, 601, 10.1016/j.cell.2006.01.021
Chenevier-Gobeaux, 2007, Implication of cytosolic phospholipase A2 (cPLA2) in the regulation of human synoviocyte NADPH oxidase (Nox2) activity, Life Sci., 81, 1050, 10.1016/j.lfs.2007.08.018
Cho, 2009, Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation, Cell, 137, 1112, 10.1016/j.cell.2009.05.037
Condino-Neto, 1998, NADPH oxidase activity and cytochrome b558 content of human Epstein-Barrvirus-transformed B lymphocytes correlate with expression of genes encoding components of the oxidase system, Arch. Biochem. Biophys., 360, 158, 10.1006/abbi.1998.0958
Costantini, 1995, Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane, FEBS Lett., 362, 239, 10.1016/0014-5793(95)00256-9
Dang, 2006, A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites, J. Clin. Invest., 16, 2033, 10.1172/JCI27544
De Keulenaer, 1998, Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle, Biochem. J., 329, 653, 10.1042/bj3290653
Degterev, 2005, Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury, Nat. Chem. Biol., 1, 112, 10.1038/nchembio711
Degterev, 2008, Identification of RIP1 kinase as a specific cellular target of necrostatins, Nat. Chem. Biol., 4, 313, 10.1038/nchembio.83
den Hertog, 2005, Redox regulation of protein-tyrosine phosphatases, Arch. Biochem. Biophys., 434, 11, 10.1016/j.abb.2004.05.024
Deshpande, 2000, Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species, FASEB J., 14, 1705, 10.1096/fj.99-0910com
Devin, 2000, The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation, Immunity, 12, 419, 10.1016/S1074-7613(00)80194-6
Devin, 2001, The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF, Mol. Cell. Biol., 21, 3986, 10.1128/MCB.21.12.3986-3994.2001
Devin, 2003, The role of the deathdomain kinase RIP in tumour-necrosis-factor-induced activation of mitogen-activated protein kinases, EMBO Rep., 4, 623, 10.1038/sj.embor.embor854
Dewas, 2003, TNF-alpha induces phosphorylation of p47(phox) in human neutrophils: partial phosphorylation of p47phox is a common event of priming of human neutrophils by TNF-alpha and granulocyte-macrophage colony-stimulating factor, J. Immunol., 171, 4392, 10.4049/jimmunol.171.8.4392
Diener, 1997, Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase, Proc. Natl. Acad. Sci. USA, 94, 9687, 10.1073/pnas.94.18.9687
Ea, 2006, Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO, Mol. Cell, 22, 245, 10.1016/j.molcel.2006.03.026
Eliopoulos, 2006, The tyrosine kinase Syk regulates TPL2 activation signals, J. Biol. Chem., 281, 1371, 10.1074/jbc.M506790200
Festjens, 2006, Butylated hydroxyanisole is more than a reactive oxygen species scavenger, Cell Death Differ., 13, 166, 10.1038/sj.cdd.4401746
Festjens, 2006, Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response, Biochim. Biophys. Acta, 1757, 1371, 10.1016/j.bbabio.2006.06.014
Festjens, 2007, RIP1, a kinase on the crossroads of a cell's decision to live or die, Cell Death Differ., 14, 400, 10.1038/sj.cdd.4402085
Fiers, 1999, More than one way to die: apoptosis, necrosis and reactive oxygen damage, Oncogene, 18, 7719, 10.1038/sj.onc.1203249
Frey, 2002, PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells, Circ. Res., 90, 1012, 10.1161/01.RES.0000017631.28815.8E
Fu, 1999, TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton, J. Biol. Chem., 274, 30729, 10.1074/jbc.274.43.30729
Gauss, 2007, Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha, J. Leukoc. Biol., 82, 729, 10.1189/jlb.1206735
Geiszt, 2003, Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells, J. Biol. Chem., 278, 20006, 10.1074/jbc.M301289200
Ghavami, 2009, Role of BNIP3 in TNF-induced cell death--TNF upregulates BNIP3 expression, Biochim. Biophys. Acta, 1793, 546, 10.1016/j.bbamcr.2009.01.002
Goossens, 1995, Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity, Proc. Natl. Acad. Sci. USA, 92, 8115, 10.1073/pnas.92.18.8115
Groen, 2005, Differential oxidation of protein-tyrosine phosphatases, J. Biol. Chem., 280, 10298, 10.1074/jbc.M412424200
Hayakawa, 2003, Evidence that reactive oxygen species do not mediate NF-kappaB activation, EMBO J., 22, 3356, 10.1093/emboj/cdg332
He, 2009, Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha, Cell, 137, 1100, 10.1016/j.cell.2009.05.021
Hitomi, 2008, Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway, Cell, 135, 1311, 10.1016/j.cell.2008.10.044
Hoeflich, 1999, Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1), Oncogene, 18, 5814, 10.1038/sj.onc.1202975
Holmgren, 2000, Antioxidant function of thioredoxin and glutaredoxin systems, Antioxid. Redox. Signal., 2, 811, 10.1089/ars.2000.2.4-811
Jamaluddin, 2007, TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway, Cell. Signal., 19, 1419, 10.1016/j.cellsig.2007.01.020
Jarvis, 2007, Mitochondria-targeted antioxidants do not prevent tumour necrosis factor-induced necrosis of L929 cells, Free Radic. Res., 41, 1041, 10.1080/10715760701557153
Jones, 1997, Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB, Mol. Cell. Biol., 17, 6970, 10.1128/MCB.17.12.6970
Kamata, 2005, Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases, Cell, 120, 649, 10.1016/j.cell.2004.12.041
Kamizato, 2009, Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon, J. Gastroenterol., 44, 1172, 10.1007/s00535-009-0119-6
Karin, 2002, NF-kappaB at the crossroads of life and death, Nat. Immunol., 3, 221, 10.1038/ni0302-221
Kelliher, 1998, The death domain kinase RIP mediates the TNF-induced NF-kappaB signal, Immunity, 8, 297, 10.1016/S1074-7613(00)80535-X
Kil, 2008, Glutathionylation regulates IkappaB, Biochem. Biophys. Res. Commun., 373, 169, 10.1016/j.bbrc.2008.06.007
Kim, 2002, The carboxy terminal C-tail of BNip3 is crucial in induction of mitochondrial permeability transition in isolated mitochondria, Arch. Biochem. Biophys., 398, 147, 10.1006/abbi.2001.2673
Kim, 2006, JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells, J. Biol. Chem., 287, 21256, 10.1074/jbc.M510644200
Kim, 2007, TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death, Mol. Cell, 26, 675, 10.1016/j.molcel.2007.04.021
Kim, 2008, TNF-alpha-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells, Exp. Mol. Med., 40, 167, 10.3858/emm.2008.40.2.167
Klatt, 2000, Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress, Eur. J. Biochem., 267, 4928, 10.1046/j.1432-1327.2000.01601.x
Kowaltowski, 2005, Redox mechanisms of cytoprotection by Bcl-2, Antioxid. Redox. Signal., 7, 508, 10.1089/ars.2005.7.508
Kroemer, 2005, Classification of cell death: recommendations of the Nomenclature Committee on Cell Death, Cell Death Differ., 72, 1463, 10.1038/sj.cdd.4401724
Kurada, 2009, MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment, J. Biol. Chem., 284, 13533, 10.1074/jbc.M808554200
Lamb, 2003, JunD mediates survival signaling by the JNK signal transduction pathway, Mol. Cell, 77, 1479, 10.1016/S1097-2765(03)00203-X
Lambeth, 2004, NOX enzymes and the biology of reactive oxygen, Nat. Rev. Immunol., 4, 181, 10.1038/nri1312
Lee, 1994, A protein kinase involved in the regulation of inflammatory cytokine biosynthesis, Nature, 372, 739, 10.1038/372739a0
Lee, 1997, TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival, Immunity, 7, 703, 10.1016/S1074-7613(00)80390-8
Lee, 2003, The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase, Mol. Cell. Biol., 23, 8377, 10.1128/MCB.23.22.8377-8385.2003
Lee, 2004, The kinase activity of Rip1 is not required for tumor necrosis factoralpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2, J. Biol. Chem., 279, 33185, 10.1074/jbc.M404206200
Lee, 2005, p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1, J. Virol., 79, 10147, 10.1128/JVI.79.16.10147-10154.2005
Lee, 2006, Link between mitochondria and NADPH oxidase 1 isozyme for the sustained production of reactive oxygen species and cell death, J. Biol. Chem., 287, 36228, 10.1074/jbc.M606702200
Legler, 2003, Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation, Immunity, 78, 655, 10.1016/S1074-7613(03)00092-X
Lei, 2002, The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase, Mol. Cell. Biol., 22, 4929, 10.1128/MCB.22.13.4929-4942.2002
Li, 2004, Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis, Biochem. J., 383, 101, 10.1042/BJ20040669
Li, 2009, Endosomal Nox2 facilitates redox-dependent induction of NF-kappaB by TNF-alpha, Antioxid. Redox. Signal., 77, 1249, 10.1089/ars.2008.2407
Li, 2009, Gelsolin, but not its cleavage, is required for TNF-induced ROS generation and apoptosis in MCF-7 cells, Biochem. Biophys. Res. Commun., 385, 284, 10.1016/j.bbrc.2009.05.078
Li, 2010, NOX3-derived reactive oxygen species promote TNF-alpha-induced reductions in hepatocyte glycogen levels via a JNK pathway, FEBS Lett., 584, 995, 10.1016/j.febslet.2010.01.044
Liedtke, 2002, Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells, Hepatology, 36, 315, 10.1053/jhep.2002.34615
Lin, 1999, Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis, Genes Dev., 73, 2514, 10.1101/gad.13.19.2514
Lin, 2004, Tumor necrosis factor-induced nonapoptotic cell death requires receptorinteracting protein-mediated cellular reactive oxygen species accumulation, J. Biol. Chem., 279, 10822, 10.1074/jbc.M313141200
Liu, 2002, Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner, Circ. Res., 90, 1259, 10.1161/01.RES.0000022160.64355.62
Liu, 2005, Role of JNK activation in apoptosis: a double-edged sword, Cell. Res., 75, 36, 10.1038/sj.cr.7290262
Liu, 2000, Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin, Mol. Cell. Biol., 20, 2198, 10.1128/MCB.20.6.2198-2208.2000
Liu, 2006, Essential role of TAK1 in thymocyte development and activation, Proc. Natl. Acad. Sci. USA, 703, 11677, 10.1073/pnas.0603089103
Liu, 2008, ROS and p53: a versatile partnership, Free Radic. Biol. Med., 44, 1529, 10.1016/j.freeradbiomed.2008.01.011
Liu, 2008, DNA-binding activity of NF-kappaB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase, Mol. Immunol., 45, 3984, 10.1016/j.molimm.2008.06.012
Los, 2002, Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling, Mol. Biol. Cell, 73, 978, 10.1091/mbc.01-05-0272
Luke, 2007, An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury, Cell, 730, 1108, 10.1016/j.cell.2007.07.013
Lupertz, 2008, Catalase overexpression impairs TNF-alpha induced NF-kappaB activation and sensitizes MCF-7 cells against TNF-alpha, J. Cell Biochem., 703, 1497, 10.1002/jcb.21538
Mahoney, 2008, Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation, Proc. Natl. Acad. Sci. USA, 705, 11778, 10.1073/pnas.0711122105
Marchetti, 1997, Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function, Eur. J. Immunol., 27, 289, 10.1002/eji.1830270142
Mariappan, 2009, TNF-induced mitochondrial damage: a link between mitochondrial complex I activity and left ventricular dysfunction, Free Radic. Biol. Med., 46, 462, 10.1016/j.freeradbiomed.2008.10.049
Meier, 1989, Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha, Biochem. J., 263, 539, 10.1042/bj2630539
Miller, 2010, A differential role for endocytosis in receptor-mediated activation of Nox1, Antioxid. Redox. Signal., 12, 583, 10.1089/ars.2009.2857
Moe, 2006, Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-alpha in human aortic smooth muscle and embryonic kidney cells, J. Cell. Mol. Med., 10, 231, 10.1111/j.1582-4934.2006.tb00304.x
Morgan, 2007, Lipid rafts and oxidative stress-induced cell death, Antioxid. Redox Signal., 9, 1471, 10.1089/ars.2007.1658
Moriguchi, 1997, A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses, EMBO J., 16, 7045, 10.1093/emboj/16.23.7045
Muppidi, 2004, Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction, Immunity, 21, 461, 10.1016/j.immuni.2004.10.001
Nakagawa, 2005, Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death, Nature, 434, 652, 10.1038/nature03317
Nakajima, 2008, Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells, Oncogene, 27, 76, 10.1038/sj.onc.1210624
Nakano, 2000, NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis, J. Biol. Chem., 275, 20533, 10.1074/jbc.M001009200
Nakano, 2006, Reactive oxygen species mediate crosstalk between NF-kappaB and JNK, Cell Death Differ., 13, 730, 10.1038/sj.cdd.4401830
Nakashima, 2002, Redox-linked signal transduction pathways for protein tyrosine kinase activation, Antioxid. Redox Signal., 4, 517, 10.1089/15230860260196326
Nakashima, 2005, Redox control of catalytic activities of membrane-associated protein tyrosine kinases, Arch. Biochem. Biophys., 434, 3, 10.1016/j.abb.2004.06.016
Newburger, 1991, In vitro regulation of human phagocyte cytochrome b heavy and light chain gene expression by bacterial lipopolysaccharide and recombinant human cytokines, J. Biol. Chem., 266, 16171, 10.1016/S0021-9258(18)98531-5
Nishitoh, 1998, ASK1 is essential for JNK/SAPK activation by TRAF2, Mol. Cell, 2, 389, 10.1016/S1097-2765(00)80283-X
Noguchi, 2005, Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death, J. Biol. Chem., 280, 37033, 10.1074/jbc.M506771200
Oliveira-Marques, 2009, Role of hydrogen peroxide in NF-kappaB activation: from inducer to modulator, Antioxid. Redox Signal., 11, 2223, 10.1089/ars.2009.2601
Omori, 2008, TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity, J. Biol. Chem., 283, 26161, 10.1074/jbc.M804513200
Ott, 2007, Mitochondria, oxidative stress and cell death, Apoptosis, 12, 913, 10.1007/s10495-007-0756-2
Ozsoy, 2008, Oxidative stress promotes ligandindependent and enhanced ligand-dependent tumor necrosis factor receptor signaling, J. Biol. Chem., 283, 23419, 10.1074/jbc.M802967200
Pantano, 2007, Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis, Am. J. Respir. Cell. Mol. Biol., 36, 473, 10.1165/rcmb.2006-0109OC
Papa, 2004, Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2, Nat. Cell. Biol., 6, 146, 10.1038/ncb1093
Paulsen, 2010, Orchestrating redox signaling networks through regulatory cysteine switches, ACS Chem. Biol., 5, 47, 10.1021/cb900258z
Pham, 2004, Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species, Cell, 119, 529, 10.1016/j.cell.2004.10.017
Poyet, 2000, Activation of the Ikappa B kinases by RIP via IKKgamma/NEMO-mediated oligomerization, J. Biol. Chem., 275, 37966, 10.1074/jbc.M006643200
Quinn, 2006, The expanding role of NADPH oxidases in health and disease: no longer just agents of death and destruction, Clin. Sci., 111, 1, 10.1042/CS20060059
Reuther-Madrid, 2002, The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor, Mol. Cell. Biol., 22, 8175, 10.1128/MCB.22.23.8175-8183.2002
Reynaert, 2006, Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta, Proc. Natl. Acad. Sci. USA, 103, 13086, 10.1073/pnas.0603290103
Rhee, 2005, Controlled elimination of intracellular H(2).O(2).: regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification. Antioxid, Redox Signal., 7, 619, 10.1089/ars.2005.7.619
Saito, 2006, Turning point in apoptosis/necrosis induced by hydrogen peroxide, Free Radic. Res., 40, 619, 10.1080/10715760600632552
Saitoh, 1998, Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1, EMBO J., 17, 2596, 10.1093/emboj/17.9.2596
Sakon, 2003, NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death, EMBO J., 22, 3898, 10.1093/emboj/cdg379
Sathyanarayana, 2002, Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3, Mol. Cell, 10, 1527, 10.1016/S1097-2765(02)00734-7
Sato, 2005, Essential function for the kinase TAK1 in innate and adaptive immune responses, Nat. Immunol., 6, 1087, 10.1038/ni1255
Sato, 2008, Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptor-interacting protein and inhibition of lysosomal cathepsin, J. Immunol., 181, 197, 10.4049/jimmunol.181.1.197
Schmidt, 1995, The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-kappa B, Chem. Biol., 2, 13, 10.1016/1074-5521(95)90076-4
Schreck, 1992, Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells, J. Exp. Med., 175, 1181, 10.1084/jem.175.5.1181
Schulze-Osthoff, 1992, Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation, J. Biol. Chem., 267, 5317, 10.1016/S0021-9258(18)42768-8
Schulze-Osthoff, 1993, Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF, EMBO J., 12, 3095, 10.1002/j.1460-2075.1993.tb05978.x
Shen, 2006, JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species, Free Radic. Biol. Med., 40, 928, 10.1016/j.freeradbiomed.2005.10.056
Shen, 2006, TNF receptor superfamily-induced cell death: redox-dependent execution, FASEB J., 20, 1589, 10.1096/fj.05-5603rev
Shen, 2004, Essential roles of receptorinteracting protein and TRAF2 in oxidative stress-induced cell death, Mol. Cell. Biol., 24, 5914, 10.1128/MCB.24.13.5914-5922.2004
Shi, 1997, Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-kappaB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- and germinal center kinase related-dependent pathway, J. Biol. Chem., 272, 32102, 10.1074/jbc.272.51.32102
Shi, 1999, TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related, J. Immunol., 163, 3279, 10.4049/jimmunol.163.6.3279
Shim, 2005, TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo, Genes Dev., 19, 2668, 10.1101/gad.1360605
Sidoti-de Fraisse, 1998, TNF-alpha activates at least two apoptotic signaling cascades, Oncogene, 17, 1639, 10.1038/sj.onc.1202094
Sies, 1997, Oxidative stress: oxidants and antioxidants, Exp. Physiol., 82, 291, 10.1113/expphysiol.1997.sp004024
St Hilaire, 2008, TNF-alpha upregulates the A2B adenosine receptor gene: The role of NAD(P)H oxidase 4, Biochem. Biophys. Res. Commun., 375, 292, 10.1016/j.bbrc.2008.07.059
Staal, 1990, Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus, Proc. Natl. Acad. Sci. USA, 87, 9943, 10.1073/pnas.87.24.9943
Tada, 2001, Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death, J. Biol. Chem., 276, 36530, 10.1074/jbc.M104837200
Takaesu, 2003, TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway, J. Mol. Biol., 326, 105, 10.1016/S0022-2836(02)01404-3
Takeda, 1999, Hydrogen peroxide induces necrosis, apoptosis, oncosis and apoptotic oncosis of mouse terminal proximal straight tubule cells, Nephron, 81, 234, 10.1159/000045282
Takeya, 2003, Novel human homologues of p47phox and p67phox participate in activation of superoxideproducing NADPH oxidases, J. Biol. Chem., 278, 25234, 10.1074/jbc.M212856200
Tang, 2001, Inhibition of JNK activation through NF-kappaB target genes, Nature, 414, 313, 10.1038/35104568
Tang, 2002, The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis, Mol. Cell. Biol., 22, 8571, 10.1128/MCB.22.24.8571-8579.2002
Teramoto, 1999, Hydrogen peroxide-induced apoptosis and necrosis in human lung fibroblasts: protective roles of glutathione, Jpn. J. Pharmacol., 79, 33, 10.1254/jjp.79.33
Tobiume, 2001, ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis, EMBO Rep., 2, 222, 10.1093/embo-reports/kve046
Tournier, 2001, MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines, Genes Dev., 15, 1419, 10.1101/gad.888501
Ushio-Fukai, 2009, Compartmentalization of redox signaling through NADPH oxidase-derived ROS, Antioxid. Redox Signal., 11, 1289, 10.1089/ars.2008.2333
Utsumi, 1992, Modulation of TNF-alpha-priming and stimulation-dependent superoxide generation in human neutrophils by protein kinase inhibitors, Arch. Biochem. Biophys., 294, 271, 10.1016/0003-9861(92)90168-V
Vallabhapurapu, 2009, Regulation and function of NF-kappaB transcription factors in the immune system, Annu. Rev. Immunol., 27, 693, 10.1146/annurev.immunol.021908.132641
Vande Velde, 2000, BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore, Mol. Cell. Biol., 20, 5454, 10.1128/MCB.20.15.5454-5468.2000
Vandenabeele, 2006, Caspase inhibitors promote alternative cell death pathways, Sci. STKE, 2006, pe44, 10.1126/stke.3582006pe44
Varfolomeev, 2008, c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation, J. Biol. Chem., 283, 24295, 10.1074/jbc.C800128200
Ventura, 2004, JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species, Genes Dev., 18, 2905, 10.1101/gad.1223004
Ventura, 2006, Chemical genetic analysis of the time course of signal transduction by JNK, Mol. Cell, 21, 701, 10.1016/j.molcel.2006.01.018
Wang, 2001, Glutathione S-transferase P1-1 (GSTP1-1). inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus, J. Biol. Chem., 276, 20999, 10.1074/jbc.M101355200
Weingartner, 2002, Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis, J. Biol. Chem., 277, 34853, 10.1074/jbc.M205149200
Wicovsky, 2007, Sustained JNK activation in response to tumor necrosis factor is mediated by caspases in a cell type-specific manner, J. Biol. Chem., 282, 2174, 10.1074/jbc.M606167200
Wong, 2010, RIPK1 is not essential for TNFR1-induced activation of NF-kappaB, Cell Death Differ., 17, 482, 10.1038/cdd.2009.178
Woo, 2006, Inhibition of receptor internalization attenuates the TNFalpha-induced ROS generation in non-phagocytic cells, Biochem. Biophys. Res. Commun., 351, 972, 10.1016/j.bbrc.2006.10.154
Wu, 2006, Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected], Nat. Cell. Biol., 8, 398, 10.1038/ncb1384
Wysk, 1999, Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression, Proc. Natl. Acad. Sci. USA, 96, 3763, 10.1073/pnas.96.7.3763
Xia, 2000, MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration, Proc. Natl. Acad. Sci. USA, 97, 5243, 10.1073/pnas.97.10.5243
Xu, 2006, Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation, J. Biol. Chem., 281, 8788, 10.1074/jbc.M508135200
Yang, 2001, The essential role of MEKK3 in TNF-induced NF-kappaB activation, Nat. Immunol., 2, 620, 10.1038/89769
Yao, 1997, Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors, J. Biol. Chem., 272, 17795, 10.1074/jbc.272.28.17795
Yazdanpanah, 2009, Riboflavin kinase couples TNF receptor 1 to NADPH oxidase, Nature, 460, 1159, 10.1038/nature08206
Yeh, 1997, Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice, Immunity, 7, 715, 10.1016/S1074-7613(00)80391-X
Yin, 1998, Involvement of p85 in p53-dependent apoptotic response to oxidative stress, Nature, 391, 707, 10.1038/35648
Yoshida, 2008, Expression of NADPH oxidases and enhanced H(2)O(2)-generating activity in human coronary artery endothelial cells upon induction with tumor necrosis factor-alpha, Int. Immunopharmacol., 8, 1377, 10.1016/j.intimp.2008.05.004
Yujiri, 2000, MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation, Proc. Natl. Acad. Sci. USA, 97, 7272, 10.1073/pnas.130176697