Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers

ACS Chemical Biology - Tập 15 Số 2 - Trang 469-484 - 2020
Ling F. Ye1, Kunal Chaudhary2, Fereshteh Zandkarimi1, Andrew Harken3, Connor J. Kinslow2, Pavan S. Upadhyayula4, Athanassios Dovas5, Dominique Higgins4, Hui Tan1, Yan Zhang1, Manuela Buonanno3, Tony J. C. Wang2,6, Tom K. Hei2,6, Jeffrey N. Bruce4, Peter Canoll5,6, Simon K. Cheng2,6, Brent R. Stockwell1,7,6
1Department of Biological Sciences, Columbia University, New York, New York 10027, United States
2Department of Radiation Oncology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York 10032, United States
3Radiological Research Accelerator Facility, Center for Radiological Research, Columbia University, Irvington, New York 10533, United States
4Department of Neurological Surgery, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York 10032, United States
5Departments of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, 1130 St. Nicholas Ave Rm.1001, New York, New York 10032, United States
6Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York 10032, United States
7Department of Chemistry, Columbia University, New York, New York 10027, United States

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