Protosappanin A exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia

Chinese Journal of Natural Medicines - Tập 15 - Trang 674-679 - 2017
Li-Chao WANG1,2, Li-Xi LIAO1, Ming-Bo ZHAO1, Xin DONG1, Ke-Wu ZENG1, Peng-Fei TU1,2
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China
2State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China

Tài liệu tham khảo

Mosher, 2014, Microglial dysfunction in brain aging and Alzheimer's disease [J], Biocheml Pharmacol, 88, 594, 10.1016/j.bcp.2014.01.008

Kang, 2014, Effect of the semen extract of Cuscuta chinensis on inflammatory responses in LPS- stimulated BV-2 microglia [J], Chin J Nat Med, 12, 573

Zeng, 2015, Caruifolin D from Artemisia absinthium L. inhibits neuroinflammation via reactive oxygen species-dependent c-jun N-terminal kinase and protein kinase c/NF-κB signaling pathways [J], Eur J Pharmacol, 767, 82, 10.1016/j.ejphar.2015.10.011

Supriady, 2015, SMEAF attenuates the production of pro-inflammatory mediators through the inactivation of Akt-dependent NF-κB, p38 and ERK1/2 pathways in LPS-stimulated BV-2 microglial cells [J], J Funct Foods, 17, 434, 10.1016/j.jff.2015.05.042

Wang, 2014, Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association with inhibiting spinal JAK2/STAT3 signaling in neuropathic pain in rats [J], Neuroscience, 273, 65, 10.1016/j.neuroscience.2014.04.052

Tong, 2013, An LC/MS/MS method for simultaneous quantitation of two homoisoflavones: protosappanin B and brazilin with hypoglycemic activity in rat plasma and its application to a comparative pharmacokinetic study in normal and streptozotocin-treated rats [J], J Ethnopharmacol, 148, 682, 10.1016/j.jep.2013.05.029

Sasaki, 2007, In vitro study for inhibition of NO production about constituents of Sappan Lignum [J], Biol Pharm Bull, 30, 193, 10.1248/bpb.30.193

Cuong, 2012, Phenolic compounds from Caesalpinia sappan heartwood and their anti-inflammatory activity [J], J Nat Prod, 75, 2069, 10.1021/np3003673

Zhang, 2014, Inhibitory activities of Lignum Sappan extractives on growth and growth-related signaling of tumor cells [J], Chin J Nat Med, 12, 607

Zeng, 2012, Protosappanin A inhibits oxidative and nitrative stress via interfering the interaction of transmembrane protein CD14 with Toll-like receptor-4 in lipopolysaccharide-induced BV-2 microglia[J], Int Immunopharmacol, 14, 558, 10.1016/j.intimp.2012.09.004

Zeng, 2014, Sesquiterpene dimer (DSF-52) from Artemisia argyi inhibits microglia-mediated neuroinflammation via suppression of NF-κB, JNK/p38 MAPKs and Jak2/Stat3 signaling pathways [J], Phytomedicine, 21, 298, 10.1016/j.phymed.2013.08.016

Zhang, 2014, Hydroxy-safflor yellow A attenuates Aβ1-42-induced inflammation by modulating the JAK2/STAT3/NF-κB pathway [J], Brain Res, 1563, 72, 10.1016/j.brainres.2014.03.036

Lv, 2015, Protective effect of Fenofibrate in renal ischemia reperfusion injury: Involved in suppressing kinase 2 (JAK2)/transcription 3 (STAT3)/p53 signaling activation [J], Pathol Biol, 63, 236, 10.1016/j.patbio.2015.07.010

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Thông tin xuất bản

Chinese Journal of Natural Medicines

Tập 15

674-679

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