Prognostic Implications of Tumor-Infiltrating Lymphocytes in Association With Programmed Death Ligand 1 Expression in Early-Stage Breast Cancer

Liotta, 2001, The microenvironment of the tumor–host interface, Nature, 411, 375, 10.1038/35077241

de Visser, 2006, Paradoxical roles of the immune system during cancer development, Nat Rev Cancer, 6, 24, 10.1038/nrc1782

Disis, 2010, Immune regulation of cancer, J Clin Oncol, 28, 4531, 10.1200/JCO.2009.27.2146

Loi, 2013, Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG02-98, J Clin Oncol, 31, 860, 10.1200/JCO.2011.41.0902

Zhang, 2003, Intratumoral T cells, recurrence and survival in epithelial ovarian cancer, N Engl J Med, 348, 203, 10.1056/NEJMoa020177

Galon, 2006, Type, density, and location of immune cells within human colorectal tumors predict clinical outcome, Science, 313, 1960, 10.1126/science.1129139

Bates, 2006, Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse, J Clin Oncol, 24, 5373, 10.1200/JCO.2006.05.9584

Seo, 2013, Tumor infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer, Br J Cancer, 109, 2705, 10.1038/bjc.2013.634

Denkert, 2010, Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer, J Clin Oncol, 28, 105, 10.1200/JCO.2009.23.7370

Mellman, 2011, Cancer immunotherapy comes of age, Nature, 21, 480, 10.1038/nature10673

Topalian, 2012, Safety, activity, and immune correlates of anti-PD-1 antibody in cancer, N Engl J Med, 366, 2443, 10.1056/NEJMoa1200690

Brahmer, 2012, Safety and activity of anti-PD-L1 antibody in patients with advanced cancer, N Engl J Med, 366, 2455, 10.1056/NEJMoa1200694

Hodi, 2010, Improved survival with ipilimumab in patients with metastatic melanoma, N Engl J Med, 363, 711, 10.1056/NEJMoa1003466

Hamanishi, 2007, Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer, Proc Natl Acad Sci U S A, 104, 3360, 10.1073/pnas.0611533104

Konishi, 2004, B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression, Clin Cancer Res, 10, 5094, 10.1158/1078-0432.CCR-04-0428

Karim, 2009, Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T cell infiltration and survival of patients with cervical carcinoma, Clin Cancer Res, 15, 6341, 10.1158/1078-0432.CCR-09-1652

Gao, 2009, Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma, Clin Cancer Res, 15, 971, 10.1158/1078-0432.CCR-08-1608

Hammond, 2010, American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer, J Clin Oncol, 28, 2784, 10.1200/JCO.2009.25.6529

McShane, 2005, Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. Reporting recommendations for tumor marker prognostic studies, J Clin Oncol, 23, 9067, 10.1200/JCO.2004.01.0454

Mittendorf, 2014, PD-L1 expression in triple negative breast cancer, Cancer Immunol Res, 2, 361, 10.1158/2326-6066.CIR-13-0127

Wimberly, 2015, PD-L1 expression correlates with tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy in breast cancer, Cancer Immunol Res, 3, 326, 10.1158/2326-6066.CIR-14-0133

Spranger, 2013, Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells, Sci Transl Med, 5, 200ra116, 10.1126/scitranslmed.3006504

Taube, 2012, Colocalization of inflammatory response with B7-H1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape, Sci Transl Med, 4, 127ra37, 10.1126/scitranslmed.3003689

Victor, 2015, Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer, Nature, 520, 373, 10.1038/nature14292

Thompson, 2006, Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up, Cancer Res, 66, 3381, 10.1158/0008-5472.CAN-05-4303

Salgado, 2015, Harmonization of the evaluation of tumor infiltrating lymphocytes (TILs) in breast cancer: recommendations by an international TILs-working group 2014, Ann Oncol, 26, 259, 10.1093/annonc/mdu450