Production of sanguinarine by suspension culture of Papayer somniferum in bioreactors

Misawa, 1991, Research activities in Japan, 3 Tam, 1980, Codeine from cell suspension cultures of Papaver somniferum, Phytochem, 19, 486, 10.1016/0031-9422(80)83215-8 Eilert, 1985, Stimulation of sanguinarine accumulation in Papaver somniferum cell cultures by fungal elicitors, J. Plant Physiol, 119, 65, 10.1016/S0176-1617(85)80216-9 Southard, 1984, Sanguinarine, a new antiplaque agent: retention and plaque specificity, J. Am. Dent. Ass, 108, 339 Gamborg, 1968, Nutrient requirements of suspension cultures of soybean root cells, Exp. Cell Res, 50, 151, 10.1016/0014-4827(68)90403-5 Kurz, 1987, Elicitor treatment: A method for metabolite production by plant cell cultures in vitro, 283 Kobayashi, 1989, Effect of oxygen supply on berberine production in cell suspension cultures and immobilized cells of Thalictrum minus, Plant Cell Rep, 8, 255, 10.1007/BF00778546 Schumacher, 1988, Partial purification and characterization of dihydrobenzophenathridine oxidase from Eschscholtzia californica cell suspension cultures, Plant Cell Rep, 7, 43, 10.1007/BF00272975 Tanahashi, 1988, One step enzymatic synthesis of dihydrosanguinarine from protopine, Tetrahedron Lett, 29, 5625, 10.1016/S0040-4039(00)80829-1 Rueffer, 1987, S-Adenosyl-l-methionine: (s)-7,8,13,14-tetrahydroberberine-cis-N-methyltransferase, a branch point enzyme in the biosynthesis of benzophenanthridine and protopine alkaloids, Tetrahedron Lett, 28, 5307, 10.1016/S0040-4039(00)96715-7 Linsmaier, 1965, Organic growth factor requirements of tobacco tissue cultures, Physiol. Plant, 18, 100, 10.1111/j.1399-3054.1965.tb06874.x Songstad, 1990, Use of nurse cultures to select for Papaver somniferum cell lines capable of enhanced sanguinarine production, J. Plant Physiol, 136, 236, 10.1016/S0176-1617(11)81672-X