Prevalence of Demodex folliculorum and Demodex brevis in patients with blepharitis and chalazion

Lindsley K, Matsumura S, Hatef E, Akpek EK (2012) Interventions for chronic blepharitis. Cochrane Database Syst Rev 5:CD005556. https://doi.org/10.1002/14651858.CD005556.pub2

Navel V, Mulliez A, Benoist d’Azy C, Baker JS, Malecaze J, Chiambaretta F, Dutheil F (2019) Efficacy of treatments for Demodex blepharitis: a systematic review and meta-analysis. Ocul Surf 17(4):655–669. https://doi.org/10.1016/j.jtos.2019.06.004

Jackson WB (2008) Blepharitis: current strategies for diagnosis and management. Can J Ophthalmol 43(2):170–179. https://doi.org/10.1139/i08-016

McCulley JP, Shine WE (2000) Changing concepts in the diagnosis and management of blepharitis. Cornea 19(5):650–658. https://doi.org/10.1097/00003226-200009000-00010

Fromstein SR, Harthan JS, Patel J, Opitz DL (2018) Demodex blepharitis: clinical perspectives. Clin Optom (Auckl) 10:57–63. https://doi.org/10.2147/OPTO.S142708

Tarkowski W, Owczynska M, Blaszczyk-Tyszka A, Mlocicki D (2015) Demodex mites as potential etiological factor in chalazion - a study in Poland. Acta Parasitol 60(4):777–783. https://doi.org/10.1515/ap-2015-0110

Liang L, Ding X, Tseng SC (2014) High prevalence of demodex brevis infestation in chalazia. Am J Ophthalmol 157:342-348e1

Mansour AM, Chan CC, Crawford MA, Tabbarah ZA, Shen D, Haddad WF, Salti I, Ghazi NG (2006) Virus-induced chalazion. Eye (Lond) 20(2):242–246. https://doi.org/10.1038/sj.eye.6701816

Burkhart CG, Burkhart CN (2008) Similar to acne vulgaris bacteria may produce the biological glue that causes plugging of the meibomian gland leading to chalazions. Clin Exp Ophthalmol 36(3):295–296. https://doi.org/10.1111/j.1442-9071.2008.01714.x

Sedzikowska A, Oseka M, Grytner-Ziecina B (2016) Ocular symptoms reported by patients infested with Demodex mites. Acta Parasitol 61(4):808–814. https://doi.org/10.1515/ap-2016-0112

Litwin D, Chen W, Dzika E, Korycinska J (2017) Human permanent Ectoparasites; recent advances on biology and clinical significance of Demodex mites: narrative review article. Iran J Parasitol 12(1):12–21

Cheng AM, Sheha H, Tseng SC (2015) Recent advances on ocular Demodex infestation. Curr Opin Ophthalmol 26(4):295–300. https://doi.org/10.1097/ICU.0000000000000168

Yam JC, Tang BS, Chan TM, Cheng AC (2014) Ocular demodicidosis as a risk factor of adult recurrent chalazion. Eur J Ophthalmol 24(2):159–163. https://doi.org/10.5301/ejo.5000341

Desch C, Nutting WB (1972) Demodex folliculorum (Simon) and D. brevis akbulatova of man: redescription and reevaluation. J Parasitol 58:169–177

Nutting WB (1976) Hair follicle mites (Acari: demodicidae) of man. Int J Dermatol 15(2):79–98. https://doi.org/10.1111/j.1365-4362.1976.tb00663.x

Yula E, Kaya O, Atambay M, Doganay S, Daldal N, Tuzcu E (2013) What is the importance of Demodex folliculorum and D. brevis in the etiology of blepharitis? Turkiye Klinikleri J Med Sci 33:420–424

Kim JH, Chun YS, Kim JC (2011) Clinical and immunological responses in ocular demodecosis. J Korean Med Sci 26(9):1231–1237. https://doi.org/10.3346/jkms.2011.26.9.1231

Murphy O, O’Dwyer V, Lloyd-McKernan A (2019) Ocular Demodex folliculorum: prevalence and associated symptoms in an Irish population. Int Ophthalmol 39(2):405–417. https://doi.org/10.1007/s10792-018-0826-1

Liu J, Sheha H, Tseng SC (2010) Pathogenic role of Demodex mites in blepharitis. Curr Opin Allergy Clin Immunol 10(5):505–510. https://doi.org/10.1097/ACI.0b013e32833df9f4

Czepita D, Kuzna-Grygiel W, Czepita M, Grobelny A (2007) Demodex folliculorum and Demodex brevis as a cause of chronic marginal blepharitis. Ann Acad Med Stetin 53(63):67

Kabatas N, Dogan AS, Kabatas EU, Acar M, Bicer T, Gurdal C (2017) The effect of Demodex infestation on blepharitis and the ocular symptoms. Eye Contact Lens 43(1):64–67. https://doi.org/10.1097/ICL.0000000000000234

Kemal M, Sumer Z, Toker MI, Erdogan H, Topalkara A, Akbulut M (2005) The Prevalence of Demodex folliculorum in blepharitis patients and the normal population. Ophthalmic Epidemiol 12(4):287–290. https://doi.org/10.1080/092865805910057

Koo H, Kim TH, Kim KW, Wee SW, Chun YS, Kim JC (2012) Ocular surface discomfort and Demodex: effect of tea tree oil eyelid scrub in Demodex blepharitis. J Korean Med Sci 27(12):1574–1579. https://doi.org/10.3346/jkms.2012.27.12.1574

Schear MJ, Milman T, Steiner T, Shih C, Udell IJ, Steiner A (2016) The Association of Demodex with Chalazia: a Histopathologic Study of the Eyelid. Ophthalmic Plast Reconstr Surg 32(4):275–278. https://doi.org/10.1097/IOP.0000000000000500

Turk M, Ozturk I, Sener AG, Kucukbay S, Afsar I, Maden A (2007) Comparison of incidence of Demodex folliculorum on the eyelash follicule in normal people and blepharitis patients. Turkiye Parazitol Derg 31(4):296–297

Wesolowska M, Knysz B, Reich A, Blazejewska D, Czarnecki M, Gladysz A, Pozowski A, Misiuk-Hojlo M (2014) Prevalence of Demodex spp. in eyelash follicles in different populations. Arch Med Sci. 10(2):319–324

Zhu M, Cheng C, Yi H, Lin L, Wu K (2018) Quantitative analysis of the bacteria in blepharitis with Demodex infestation. Front Microbiol 9:1719. https://doi.org/10.3389/fmicb.2018.01719

Bitton E, Aumond S (2021) Demodex and eye disesae: a review. Clin Exp Optom 104(3):285–294. https://doi.org/10.1111/cxo.13123

Zeytun E, Karakurt Y (2019) Prevalence and load of Demodex folliculorum and Demodex brevis (Acari: demodicidae) in patients with chronic blepharitis in the province of Erzincan. Turkey J Med Entomol 56(1):2–9. https://doi.org/10.1093/jme/tjy143

Gao YY, Xu DL, Huang lJ, Wang R, Tseng SC (2012) Treatment of ocular itching associated with ocular demodicosis by 5% tea tree oil ointment. Cornea 31:14–17. https://doi.org/10.1097/ICO.0b013e31820ce56c

Kasetsuwan N, Kositphipat K, Busayarat M, Threekhan P, Preativatanyou K, Phumee A, Siriyasatien P (2017) Prevalence of ocular demodicosis among patients at tertiary care center, Bangkok Thailand. Int J Ophthalmol 10(1):122–127. https://doi.org/10.18240/ijo.2017.01.20

Mongi F, Laconte L, Casero RD (2018) Demodex genus: colonizing parasites of healthy people or mites associated with ocular pathology? Rev Argent Microbiol 50(4):369–373. https://doi.org/10.1016/j.ram.2017.09.002

Zhang XB, Ding YH, He W (2018) The association between demodex infestation and ocular surface manifestations in meibomian gland dysfunction. Int J Ophthalmol 11(4):589–592. https://doi.org/10.18240/ijo.2018.04.08

Inceboz T, Yaman A, Over L, Ozturk AT, Akisu C (2009) Diagnosis and treatment of demodectic blepharitis. Turkiye Parazitol Derg 33(1):32–36

Kaya OA, Akkucuk S, Ilhan G, Guneri CO, Mumcuoglu K (2019) The importance of Demodex Mites (Acari: demodicidae) in patients with sickle cell anemia. J Med Entomol 56(3):599–602. https://doi.org/10.1093/jme/tjy225

Yamashita LS, Cariello AJ, Geha NM, Yu MC, Hofling-Lima AL (2011) Demodex folliculorum on the eyelash follicle of diabetic patients. Arq Bras Oftalmol 74(6):422–424. https://doi.org/10.1590/s0004-27492011000600008