Nhà máy thực vật sản xuất hợp chất chống ung thư: Một góc nhìn từ văn hóa mô

Abdullah ASH, Mohammed AS, Abdullah R, Mirghani MES, Qubaisi MA (2014) Cytotoxic effects of Mangifera indica L. kernel extract on human breast cancer (MCF-7 and MDA-MB-231 cell lines) and bioactive constituents in the crude extract. BMC Complement Altern Med 14:199

Abhyankar G, Suprasannab P, Pandey BN, Mishra KP, Rao KV, Reddy VD (2010) Hairy root extract of Phyllanthus amarus induces apoptotic cell death in human breast cancer cells. Innov Food Sci Emerg Technol 11:526–532

Abotaleb M, Samuel SM, Varghese E, Varghese S, Kubatka P, Liskova A, Busselberg D (2019) Flavonoids in cancer and apoptosis. Cancers 11(1):28

Ahmed A, Ali M, El-Kholie E, El-Garawani I, Sherif N (2016) Anticancer activity of Morus nigra on human breast cancer cell line (MCF-7): the role of fresh and dry fruit extracts. J Biosci Appl Res 2(6):352–361

Ahmed SS, Faten ZM, Al-shimaa MA (2017) In vitro studies on anticancer activity of capsaicin a component of hot chili pepper against human hepatocellular carcinoma cells. Int J Cell Sci Mol Biol 2(4):555591.

Alagarsamy K, Shamala LF, Wei S (2018) Protocol: High-efficiency in-planta Agrobacterium-mediated transgenic hairy root induction of Camellia sinensis var. sinensis. Plant Methods 14:17

Al-Asmari AK, Albalawi SM, Athar MT, Khan AQ, Al-Shahrani HA, Islam M (2015) Moringa oleifera as an anti-cancer agent against breast and colorectal cancer cell lines. PLoS ONE 10(8):e0135814

Al-Dabbagh B, Elhaty IA, Elhaw M, Murali C, Al-Mansoori A, Awad B, Amin A (2019) Antioxidant and anticancer activities of chamomile (Matricaria recutita L.). BMC Res Notes 12:3

Alotaibi KS, Li H, Rafi R, Siddiqui RA (2015) Papaya black seeds have beneficial anticancer effects on PC-3 prostate cancer cells. J Cancer Metastasis Treat 3:161–168

Al-Sokari SS, El-Sheikha AF (2015) In vitro antimicrobial activity of crude extracts of some medicinal plants from Al-Baha region in Saudi Arabia. J Food Nutr Sci 3(1–2):74–78

Amaral RG, Santos SA, Andrade LN, Severino P, Carvalho AA (2019) Natural products as treatment against cancer: a historical and current vision. Clin Oncol 4:1562

Aminin DL, Menchinskaya ES, Pisliagin EA, Silchenko AS, Avilov SA, Kalinin VI (2015) Anticancer activity of sea cucumber triterpene glycosides. Mar Drugs 13:1202–1223

Ansari JA, Ahmad MK, Khan AR, Fatima N, Khan HJ, Rastogi N, Mishra DP, Mahdi AA (2016) Anticancer and antioxidant activity of Zingiber officinale Roscoe rhizome. Indian J ExpBiol 54:767–773

Antolak H, Kregiel D (2017) Food preservatives from plants. In: Karunaratne N (ed) Food additives. Innpotech Open Publishing, pp 45–71

Ardalani H, Avan A, Ghayour-Mobarhan M (2017) Podophyllotoxin: a novel potential natural anticancer agent. Avicenna J Phytomed 7(4):285–294

Balandrin MJ, Klocke JA (1988) Medicinal, aromatic and industrial materials from plants. In: Bajaj YPS (ed) Biotechnology in agriculture and forestry. Medicinal and aromatic plant. Springer, Berlin, pp 1–36

Baskaran K, Srinivas K, Kulkarni RN (2013) Two induced macro-mutants of periwinkle with enhanced contents of leaf and root alkaloids and their inheritance. Ind Crops Prod 43:701–703

Bedi A, Adholeya A, Deshmukh SK (2017) Novel anticancer compounds from endophytic fungi. Curr Biotechnol 6(1):1–17

Bernabeu E, Cagel M, Lagomarsino E, Moretton M, Chiappetta DA (2017) Paclitaxel: what has been done and the challenges remain ahead. Int J Pharm 526:474–495

Bonner J (1936) Plant tissue cultures from a hormone point of view. Proc Natl Acad Sci USA 22(6):426–430

Boy HIA, Rutilla AJH, Santos KA, Ty AMT, Yu AI, Mahboob T et al (2018) Recommended medicinal plants as source of natural products: a review. Digital Chin Med 1:131–142

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68(6):394–424

Chan HK, Ismail S (2014) Side effects of chemotherapy among cancer patients in a Malaysian general hospital: experiences, perceptions and informational needs from clinical pharmacists. Asian Pac J Cancer Prev 15(13):5305–5309

Chung IM, Kaliyaperumal R, Rajakumar G, Thiruvengadam M (2016) Production of glucosinolates, phenolic compounds and associated gene expression profiles of hairy root cultures in turnip (Brassica rapa sp. rapa). 3 Biotech 6(2):175

Dabrowska A, Thaul S (2018) How FDA approves drugs and regulates their safety and effectiveness. Congress Res Serv 7–5700:1–25

Deepthi S, Satheeshkumar K (2016) Enhanced camptothecin production induced by elicitors in the cell suspension cultures of Ophiorrhiza mungos Linn. Plant Cell Tiss Organ Cult 124:483–493. https://doi.org/10.1007/s11240-015-0908-y

Ekor M (2014) The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmocol 4(177):177

Elshafie HS, Armentano MF, Carmosino M, Bufo SA, Feo VD, Camele I (2017) Cytotoxic activity of Origanum vulgare L. on hepatocellular carcinoma cell line HepG2 and evaluation of its biological activity. Molecules 22:1435

El-Sheikha AF (2017) Medicinal Plants: ethno-uses to biotechnology era. In: Malik S (ed) Biotechnology and production of anticancer compounds. Springer, Berlin, pp 1–38

Esghaei M, Ghaffari H, Rahimi EB, Ebrahimi TZ, Bokharaei SF, Motevalian M (2018) Evaluation of anticancer activity of Camellia sinensis in the caco-2 colorectal cancer cell line. Asian Pac J Cancer Prev 19(6):1697–1701

Flores HE, Filner P (1985) Metabolic relationships of putrescine, GABA and alkaloids in cell and root cultures of Solanaceae. In: Neumann KH, Barz W, Reinhard E (eds) Primary and secondary metabolism of plant cell culture. Springer, Berlin, pp 174–185

Fragis M, Murayyan AI, Neethirajan S (2018) Cytotoxic activity and anti-cancer potential of Ontario grown onion extracts against breast cancer cell lines. Funct Foods Health Dis 8(3):159–174

Gharelo RS, Oliaei ED, Bandehagh A, Khodadadi E, Noparvar PM (2016) Production of therapeutic proteins through plant tissue and cell culture. J Biosci Biotechnol 5(1):93–104

Gonclaves S, Romano A (2018) Production of plant secondary metabolites by using biotechnological tools. In: Ramasamy VK (ed) Secondary metabolites—sources and applications. Innpotech Open Publishing, London, pp 81–99

Guo Z (2017) The modification of natural products for medical use. Acta Pharm Sin B 7:119–136

Haung P, Xia L, Liu W (2018) Hairy root induction and benzylisoquinoline alkaloid production in Macleaya cordata. Sci Rep 8:11986

Holland T, Sack M, Rademacher T, Schmale K, Altmann F, Stadlmann J, Fischer R, Hellwig S (2010) Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full size antibody in BY 2 suspension culture. Biotechnol Bioeng 107(2):278–289

Jasmine R, Manikandan K, Karthikeyan K (2015) Evaluating the antioxidant and anticancer activity of Ficus carica fruits. Afr J Biotech 14(7):634–641

Kaçar YA, Faber B (2012) Micropropagation of banana. In: Loyola-Vargas VM, Ochoa-Alejo N (eds) Plant cell culture protocols. Humana Press, Totowa, NJ, pp 143–151

Kannabiran K, Rajamani K, Suresh J, Joel JR, Uma D (2017) Variability in alkaloid content and phytochemical profile of periwinkle (Catharanthus roseus L.) cv. Local through gamma and ethyl methane sulphonate. J Pharmacogn Phytochem 6(5):2528–2532

Karimi N, Behbahani M, Dini G, Razmjou A (2018) Enhancing the secondary metabolite and anticancer activity of Echinacea purpurea callus extracts by treatment with biosynthesized ZnO nanoparticles. Adv Nat Sci Nanosci Nanotechnol 9:045009

Khan T, Gurav P (2017) PhytoNanotechnology: enhancing delivery of plant based anti-cancer drugs. Front Pharmacol 8:1002

Khatodia S, Biswas KA (2014) Comparative study of hairy root culture induction efficiency in four medicinally important plants using Agrobacterium rhizogenes. Int J Curr Microbiol Appl Sci 3(5):625–633

Kumar S, Bajaj S, Bodla RB (2016) Preclinical screening methods in cancer. Indian J Pharmacol 48(5):481–486

Kuttan R, Bhanumathy P, Nirmala K, George MC (1985) Potential anticancer activity of turmeric (Curcuma longa). Cancer Lett 29:197–202

Lalaleo L, Testillano P, Risueno MC, Cusido RM, Palazon J, Alcazar R, Bonfill M (2018) Effect of in vitro morphogenesis on the production of podophyllotoxin derivatives in callus cultures of Linum album. J Plant Physiol 228:47–58

Larasati YA, Putri DDP, Utomo RY, Hermawan A, Meiyanto E (2014) Combination of cisplatin and cinnamon essential oil inhibits HeLa Cells proliferation through cell cycle arrest. J Appl Pharm Sci 4(12):014019

Lima A, Oliveira J, Saude F, Mota J, Ferreira RB (2017) Proteins in Soy might have a higher role in cancer prevention than previously expected: soybean protein fractions are more effective mmp-9 inhibitors than non-protein fractions, even in cooked seeds. Nutrients 9(201):1–16

Liu H, Schmitz JC, Wei J, Cao S, Beumer JH, Strychor S, Cheng L, Liu M, Wang C, Wu N, Zhao X, Zhang Y, Liao J, Chu E, Lin X (2014) Clove extract inhibits tumor growth and promotes cell cycle arrest and apoptosis. Oncol Res 21(5):247–259

Liu HT, Ho YS (2018) Anticancer effect of curcumin on breast cancer and stem cells. Food Sci Human Wellness 2:134–137

Mazri MA, Meziani R (2015) Micropropagation of date palm: a review. Cell Dev Biol 4(3):160

Mirmalek SA, Azizi MA, Jangholi E, Yadollah-Damavandi S, Javidi MA, Parsa Y et al (2016) Cytotoxic and apoptogenic effect of hypericin, the bioactive component of Hypericum perforatum on the MCF-7 human breast cancer cell line. Cancer Cell Int 16:3

Mishra MR, Srivastava RK, Akhtar N (2018) Enhanced alkaloid production from cell culture system of Catharanthus roseus in combined effect of nutrient salts, sucrose and plant growth regulators. J Biotechnol Biomed Sci 1(4):14–34

Mishra M, Shukla N, Chandra R (2007) Micropropagation of papaya (Carica papaya L.). In: Mohan Jain S, Häggman H (eds) Protocols for micropropagation of woody trees and fruits. Springer, Dordrecht, pp 437–441

Modi AR, Patil G, Kumar N, Singh AS, Subhash N (2012) A simple and efficient in vitro mass multiplication procedure for Stevia rebaudiana Bertoni and analysis of genetic fidelity of in vitro raised plants through RAPD. Sugar Tech 14(4):391–397

Mohammed A, Chiruvella KK, Rao YK, Geethangili M, Raghavan SC, Ghanta RG (2015) In vitro production of Echioidinin, 7-O-Methywogonin from callus cultures of Andrographislineata and their cytotoxicity on cancer cells. PLoS ONE 10(10):e0141154

Mojica BE, Fong LE, Biju D, Muharram A, Davis IM, Vela KO et al (2018) The impact of the roast levels of coffee extracts on their potential anticancer activities. J Food Sci 83(4):1125–1130

More NV, Kharat AS (2016) Antifungal and anticancer potential of Argemone mexicana L. Med 3:28

Ovadje P, Ammar S, Guerrero JA, Arnason JT, Pandey S (2016) Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways. Oncotarget 7(45):73080–73100

Park GH, Park JH, Song HM, Eo HJ, Kim MK, Lee JW, Lee MH, Cho KH, Lee JR, Cho HJ, Jeong J, B. (2014) Anticancer activity of ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells. BMC Complement Altern Med 23(14):408

Parsons J, Wirth S, Dominguez M, Bravo-Almonacid F, Giulietti AM, Talou JR (2010) Production of human epidermal growth factor (hEGF) by in vitro cultures of Nicotiana tabacum: effect of tissue differentiation and sodium nitroprusside addition. Int J BiotechnolBiochem 6:131–138

Pengo N, Prak K, Costa JR, Luft C, Agrotis A, Freeman J, Gewinner CA, Chan AWE, Selwood DL, Kriston-Vizi J, Ketteler R (2018) Identification of kinases and phosphatases that regulate ATG4B activity by siRNA and small molecule screening in cells. Front Cell Dev Biol l 6:148

Prashant A, Rangaswamy C, Yadav AK, Reddy V, Sowmya MN, Madhunapantula S (2017) In vitro anticancer activity of ethanolic extracts of Piper nigrum against colorectal carcinoma cell lines. Int J Appl Basic Med Res 7:67–72

Przychodzen P, Wyszkowska R, Gorzynik-Debicka M, Kostrzewa T, Kuban-Jankowska A, Gorska-Ponikowska M (2019) Anticancer potential of Oleuropein, the polyphenol of olive oil, with 2-methoxyestradiol, separately or in combination, in human osteosarcoma cells. Int Inst Anticancer Res 39(3):1243–1251

Rai V, Tandon PK, Khatoon S (2014) Effect of chromium on antioxidant potential of Catharanthus roseus varieties and production of their anticancer alkaloids: vincristine and vinblastine. BioMed Res Int 934182:1–10

Rao RS, Ravishankar GA (2002) Plant cell cultures: chemical factories of secondary metabolites. Bio-technol Adv 20:101–153

Rao S, Nadumane VK (2015) Evaluation of the anticancer potential of coffee beans: an in vitro study. Indian J Trad Knowl 15(2):266–271

Ravindranathan P, Pasham D, Goel A (2019) Oligomericproanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cells. Carcinogenesis 40:412–421

Renouard S, Corbin C, Drouet S, Medvedec B, Doussot J, Colas C et al (2018) Investigation of Linum flavum (L.) hairy root cultures for the production of anticancer aryltetralin lignans. Int J Mol Sci 19(990):1–18

Richter LJ, Thanavala Y, Arntzen CJ, Mason HS (2000) Production of hepatitis B surface antigen in transgenic plants for oral immunization. Nat Biotechnol 18(11):1167–1171

Roduan MRM, Hamid RA, Sulaiman H, Mohtarrudin N (2017) Annona muricata leaves extracts prevent DMBA/TPA-induced skin tumorigenesis via modulating antioxidants enzymes system in ICR mice. Biomed Pharmacother 94:481–488

Santhi KS, Sengottuvel R (2016) Qualitative and quantitative phytochemical analysis of Moringa concanensis Nimmo. Int J Curr Microbiol Appl Sci 5:633–640

Sarmadi M, Karimi N, Palazón J, Ghassempour A, Mirjalili MH (2018) The effects of salicylic acid and glucose on biochemical traits and taxane production in a Taxus baccata callus culture. Plant Physiol Biochem 132:271–280

Seca AML, Pinto DCGA (2018) Plant secondary metabolites as anticancer agents: successes in clinical trials and therapeutic application. Int J Mol Sci 19:263

Sevimli-Gur C, Cetin B, Akay S, Gulce-Iz S, Yesil-Celiktas O (2013) Extracts from black carrot tissue culture as potent anticancer agents. Plant Foods Hum Nutr 68(3):293–298

Sharma V, Hussain S, Gupta M, Saxena AK (2014) In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells. Indian J Biochem Biophys 51(5):416–419

Shin S, Moon SY, Kim WY, Paek SM, Park HH, Lee CS (2018) Structure-based classification and anti-cancer effects of plant metabolites. Int J Mol Sci 19:2651

Singh S, Verma SK, Singh SK (2017) In vitro anticancer activity of Achyranthes aspera root extract against different human cancer cell lines. Biolife 5(1):119–122

Sivanandhan G, Selvaraj N, Ganapathi A, Manickavasagam M (2014) Enhanced biosynthesis of withanolides by elicitation and precursor feeding in cell suspension culture of Withania somnifera (L) Dunal in shake-flask culture and bioreactor. PLoS ONE 9(8):e104005

Tashackori H, Sharifi M, Chashmi NA, Behmanesh M, Safaie N (2018) Piriformospora indica cell wall modulates gene expression and metabolite profile in Linum album hairy roots. Planta 248(5):1289–1306

Thompson M, Schmelz EM, Bickford L (2019) Anticancer properties of cinnamon oil and its active component, trans-cinnamaldehyde. J Nutr Food Sci 9:1

Thorpe TA (2007) History of plant tissue culture. Mol Biotechnol 37(2):169–180

Tundis R, Loizza MR, Bonesi M, Peruzzi L, Efferth T (2019) Daphne striata Tratt. and D. mezereum L.: a study of anti-proliferative activity towards human cancer cells and antioxidant properties. Nat Prod Res 33(12):1809–1812

Vallianou NJ, Evangelopoulos A, Schizas N, Kazazis C (2015) Potential anticancer properties and mechanisms of action of curcumin. Anticancer Res 35:645–652

Vandermies M, Fickers P (2019) Bioreactor-scale strategies for the production of recombinant protein in the yeast Yarrowia lipolytica. Microorganisms 7(2):40

Wang L, Wang J, Fang L, Zang Z, Zhi D, Wang S et al (2014) Anticancer activities of citrus peel polymethoxyflavones related to angiogenesis and others. J Biomed Biotechnol 453972:1–10

Weathers PJ, Towler MJ, Xu J (2010) Bench to batch: advances in plant cell culture for producing useful products. App Microbiol Biotechnol 85(5):1339–1351

Wetterauer B, Wildi E, Wink M (2018) Production of the anticancer compound camptothecin in root and hairy root cultures of Ophiorrhiza mungos L. In: Kumar N (ed) Biotechnological approaches for medicinal and aromatic plants. Springer, Singapore, pp 303–341

Yang XZ, Zheng H, Ye Q, Li RY, Chen Y (2015) Essential oil of Cinnamon exerts anti-cancer activity against head and neck squamous cell carcinoma via attenuating epidermal growth factor receptor-tyrosine kinase. JBUON 20(6):1518–1525

Yao H, Liu J, Xu S, Zhu Z, Xu J (2017) The structural modification of natural products for novel drug discovery. Expert Opin Drug Discov 12:121–140

Zhong C, Hu D, Hou LB, Song LY, Zhang YJ, Xie Y, Tian L, W. (2017) Phenolic compounds from the rhizomes of Smilax china L. and their anti-Inflammatory activity. Molecues 22(515):1–8

Zhu J, Wang M, Wen W, Yu R (2015) Biosynthesis and regulation of terpenoid indole alkaloids in Catharanthus roseus. Pharmacogn Rev 9(17):24