Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

Immunity - Tập 26 - Trang 433-443 - 2007
Thirumala-Devi Kanneganti1, Mohamed Lamkanfi1, Yun-Gi Kim1, Grace Chen2, Jong-Hwan Park1, Luigi Franchi1, Peter Vandenabeele3, Gabriel Núñez1
1Department of Pathology, Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
2Department of Internal Medicine, Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
3Department of Molecular Biomedical Research, Molecular Signalling and Cell Death Unit, Flanders Interuniversity Institute for Biotechnology and Ghent University, Technologiepark 927, B-9052 Zwijnaarde, Belgium

Tài liệu tham khảo

Abeele, 2006, Ca(2+)-independent phospholipase A(2)-dependent gating of TRPM8 by lysophospholipids, J. Biol. Chem., 281, 40174, 10.1074/jbc.M605779200 Agostini, 2004, NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder, Immunity, 20, 319, 10.1016/S1074-7613(04)00046-9 Amer, 2006, Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf, J. Biol. Chem., 281, 35217, 10.1074/jbc.M604933200 Cerretti, 1992, Molecular cloning of the interleukin-1 beta converting enzyme, Science, 256, 97, 10.1126/science.1373520 Dinarello, 1996, Biologic basis for interleukin-1 in disease, Blood, 87, 2095, 10.1182/blood.V87.6.2095.bloodjournal8762095 Dinarello, 2006, Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process, Am. J. Clin. Nutr., 83, 447S, 10.1093/ajcn/83.2.447S Dowds, 2004, Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC, J. Biol. Chem., 279, 21924, 10.1074/jbc.M401178200 Dunzendorfer, 2004, TLR4 is the signaling but not the lipopolysaccharide uptake receptor, J. Immunol., 173, 1166, 10.4049/jimmunol.173.2.1166 Ferrari, 2006, The P2X7 receptor: a key player in IL-1 processing and release, J. Immunol., 176, 3877, 10.4049/jimmunol.176.7.3877 Franchi, 2006, Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in Salmonella-infected macrophages, Nat. Immunol., 7, 576, 10.1038/ni1346 Franchi, 2006, Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense, J. Immunol., 177, 3507, 10.4049/jimmunol.177.6.3507 Gurcel, 2006, Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival, Cell, 126, 1135, 10.1016/j.cell.2006.07.033 Hoffman, 2004, Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist, Lancet, 364, 1779, 10.1016/S0140-6736(04)17401-1 Kanneganti, 2006, Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA, J. Biol. Chem., 281, 36560, 10.1074/jbc.M607594200 Kanneganti, 2006, Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3, Nature, 440, 233, 10.1038/nature04517 Kawai, 2006, TLR signaling, Cell Death Differ., 13, 816, 10.1038/sj.cdd.4401850 Kawai, 2001, Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes, J. Immunol., 167, 5887, 10.4049/jimmunol.167.10.5887 Khakh, 2006, P2X receptors as cell-surface ATP sensors in health and disease, Nature, 442, 527, 10.1038/nature04886 Kuida, 1995, Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme, Science, 267, 2000, 10.1126/science.7535475 Labasi, 2002, Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response, J. Immunol., 168, 6436, 10.4049/jimmunol.168.12.6436 Lamkanfi, 2004, Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity, J. Biol. Chem., 279, 24785, 10.1074/jbc.M400985200 Li, 1995, Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock, Cell, 80, 401, 10.1016/0092-8674(95)90490-5 Liu-Bryan, 2005, Monosodium urate and calcium pyrophosphate dihydrate (CPPD) crystals, inflammation, and cellular signaling, Joint Bone Spine, 72, 295, 10.1016/j.jbspin.2004.12.010 Locovei, 2007, Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex, FEBS Lett., 581, 483, 10.1016/j.febslet.2006.12.056 Mackey, 2002, RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis, Cell, 108, 743, 10.1016/S0092-8674(02)00661-X Mackey, 2003, Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance, Cell, 112, 379, 10.1016/S0092-8674(03)00040-0 Maeda, 2005, Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing, Science, 307, 734, 10.1126/science.1103685 Mariathasan, 2004, Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf, Nature, 430, 213, 10.1038/nature02664 Mariathasan, 2006, Cryopyrin activates the inflammasome in response to toxins and ATP, Nature, 440, 228, 10.1038/nature04515 Martinon, 2002, The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta, Mol. Cell, 10, 417, 10.1016/S1097-2765(02)00599-3 Martinon, 2006, Gout-associated uric acid crystals activate the NALP3 inflammasome, Nature, 440, 237, 10.1038/nature04516 Miao, 2006, Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf, Nat. Immunol., 7, 569, 10.1038/ni1344 Molofsky, 2006, Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection, J. Exp. Med., 203, 1093, 10.1084/jem.20051659 Ozoren, 2006, Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes, J. Immunol., 176, 4337, 10.4049/jimmunol.176.7.4337 Park, 2007, RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs, J. Immunol., 178, 2380, 10.4049/jimmunol.178.4.2380 Pelegrin, 2006, Pannexin-1 couples to maitotoxin and nigericin-induced IL-1beta release through a dye-uptake independent pathway, J. Biol. Chem., 282, 2386, 10.1074/jbc.M610351200 Pelegrin, 2006, Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor, EMBO J., 25, 5071, 10.1038/sj.emboj.7601378 Seki, 2001, Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta, J. Immunol., 166, 2651, 10.4049/jimmunol.166.4.2651 Simberg, 2004, DOTAP (and other cationic lipids): chemistry, biophysics, and transfection, Crit. Rev. Ther. Drug Carrier Syst., 21, 257, 10.1615/CritRevTherDrugCarrierSyst.v21.i4.10 Solle, 2001, Altered cytokine production in mice lacking P2X(7) receptors, J. Biol. Chem., 276, 125, 10.1074/jbc.M006781200 Surprenant, 1996, The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7), Science, 272, 735, 10.1126/science.272.5262.735 Sutterwala, 2006, Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1, Immunity, 24, 317, 10.1016/j.immuni.2006.02.004 Thome, 1998, Identification of CARDIAK, a RIP-like kinase that associates with caspase-1, Curr. Biol., 8, 885, 10.1016/S0960-9822(07)00352-1 Thornberry, 1992, A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes, Nature, 356, 768, 10.1038/356768a0 Ting, 2005, CATERPILLER: a novel gene family important in immunity, cell death, and diseases, Annu. Rev. Immunol., 23, 387, 10.1146/annurev.immunol.23.021704.115616 Walev, 2001, Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O, Proc. Natl. Acad. Sci. USA, 98, 3185, 10.1073/pnas.051429498 Yoo, 2002, Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1, Biochem. Biophys. Res. Commun., 299, 652, 10.1016/S0006-291X(02)02714-6 Zhou, 2004, Lipopolysaccharide could be internalized into human peripheral blood mononuclear cells and elicit TNF-alpha release, but not via the pathway of toll-like receptor 4 on the cell surface, Cell Mol. Immunol., 1, 373