Oxygen heterocyclic Diels-Alder-Type sesquiterpenoid dimers from Vernonia anthelmintica

Alley, 1988, Feasibility of drug screening with panels of human-tumor cell-lines using a microculture tetrazolium assay, Cancer Res., 48, 589 Asaka, 1977, Studies on a bitter principle from vernonia-anthelmintica, Phytochemistry, 16, 1838, 10.1016/0031-9422(71)85109-9 Bannwarth, 2018, GFN2-xTB – an accurate and broadly parametrized self-consistent tight-binding quantum chemical method with multipole electrostatics and density-dependent dispersion contributions, J. Chem. Theor. Comput., 15, 1652, 10.1021/acs.jctc.8b01176 Furche, 2013, Turbomole, WIREs Computational Molecular Science, 4, 91, 10.1002/wcms.1162 Kupchan, 1968, Tumor inhibitors. XXXI. Vernolepin, a novel elemanolide dilactone tumor inhibitor from Vernonia hymenolepis, J. Am. Chem. Soc., 90, 3596, 10.1021/ja01015a073 Lin, 1985 Liu, 2010, Vernodalidimers A and B, novel orthoester elemanolide dimers from seeds of Vernonia anthelmintica, Tetrahedron Lett., 51, 6584, 10.1016/j.tetlet.2010.10.031 Lu, T., Molclus Program, Version 1.9.9.9. http://www.keinsci.com/research/molclus.html. Luo, 2011, Isolation and structure determination of a sesquiterpene lactone (vernodalinol) from Vernonia amygdalina extracts, Pharm. Biol., 49, 464, 10.3109/13880209.2010.523429 Maimaiti, 2017, Two new compounds from the seeds of Vernonia anthelmintica, J. Asian Nat. Prod. Res., 19, 862, 10.1080/10286020.2016.1269760 O'Boyle, 2011, Open Babel: an open chemical toolbox, J. Cheminf., 3, 33, 10.1186/1758-2946-3-33 Rakhymbay, 2019, Phenolic compounds from Vernonia anthelmintica seeds, Chem. Nat. Compd., 55, 991, 10.1007/s10600-019-02874-6 Thongnest, 2019, Vernodalidimer L, a sesquiterpene lactone dimer from Vernonia extensa and anti-tumor effects of vernodalin, vernolepin, and vernolide on HepG2 liver cancer cells, Bioorg. Chem., 92, 103197, 10.1016/j.bioorg.2019.103197 Toyang, 2013, Cytotoxic sesquiterpene lactones from the leaves of Vernonia guineensis Benth. (Asteraceae), J. Ethnopharmacol., 146, 552, 10.1016/j.jep.2013.01.022 Turak, 2018, Three new elemanolides from the seeds of Vernonia anthelmintica, J. Asian Nat. Prod. Res., 20, 313, 10.1080/10286020.2017.1343304 Turak, 2015, Elemanolide dimers from seeds of Vernonia anthelmintica, Fitoterapia, 104, 23, 10.1016/j.fitote.2015.04.013 Turak, 2017, Pseudo-disesquiterpenoids from seeds of Vernonia anthelmintica and their biological activities, Phytochem Lett, 21, 163, 10.1016/j.phytol.2017.06.017