Oxygen Free Radicals and Human Diseases

SAGE Publications - Tập 111 Số 5 - Trang 172-177 - 1991
Okezie I. Aruoma1, Harparkash Kaur1, Barry Halliwell2
1Biochemistry Department, University of London King's College, Strand, London WC2R 2LS, U.K.
2Division of Pulmonary-Critical Care Medicine, University of California Davis Medical Centre, 4301 X Street, Sacramento, CA 958157, U.S.A.

Tóm tắt

FREE RADICALS and other reactive oxygen species are constantly formed in the human body. Many of them serve useful physiological func tions, but they can be toxic when generated in excess and this toxicity is often aggravated by the presence of ions of such transition metals as iron or copper. Excess generation of reactive oxygen species within tissues can damage DNA, lipids, proteins and carbohydrates. Which of these is the most important target of damage depends upon the cell type subjected to the oxidative stress and upon how it is imposed.

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SAGE Publications

Tập 111 Số 5

172-177

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