Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer

Human Pathology - Tập 23 Số 9 - Trang 974-979 - 1992
D. Craig Allred1,2,3,4,5, Gary M. Clark1,2,3,4,5, Rafael Molina1,2,3,4,5, Atul K. Tandon1,2,3,4,5, Stuart J. Schnitt1,2,3,4,5, Kennedy W. Gilchrist1,2,3,4,5, C. Kent Osborne1,2,3,4,5, Douglass C. Tormey1,2,3,4,5, William McGuire1,2,3,4,5
1Clinical Cancer Center, University of Wisconsin, Madison, WI, USA
2Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI, USA
3Department of Pathology, Beth Israel Hospital, Boston, MA, USA
4Departments of Pathology and Medicine/Oncology, University of Texas Health Science Center, San Antonio, TX, USA
5Laboratorio de Bioquimica, Hospital Clinico Provincial, Barcelona, Spain

Tóm tắt

Từ khóa


Tài liệu tham khảo

Shih, 1981, Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts, Nature, 290, 261, 10.1038/290261a0

Padhy, 1982, Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas, Cell, 28, 865, 10.1016/0092-8674(82)90065-4

Schecter, 1984, The c-neu oncogene: An erbB-related gene encoding a 185,000 MW tumour antigen, Nature, 312, 513, 10.1038/312513a0

Coussens, 1985, Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene, Science, 230, 1132, 10.1126/science.2999974

Semba, 1985, A v-erb related proto-oncogene, c-erbB-2, is distinct from c-erbB-1/epidermal growth factor receptor gene and is amplified in a human salivary gland adenocarcinoma, 82, 6497

King, 1985, Amplification of a novel v-erbB-related gene in human mammary carcinoma, Science, 229, 974, 10.1126/science.2992089

Schecter, 1985, The c-neu gene: An erbB-homologous gene distinct from and unlinked to genes encoding the EFG receptor, Science, 229, 976, 10.1126/science.2992090

Drebin, 1986, Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen, 83, 9129

Lupu, 1991, Direct interaction of a ligand for the erbB-2 oncogene produced with the EGF receptor and p185 erbB-2, Science, 249, 1552, 10.1126/science.2218496

Slamon, 1987, Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene, Science, 235, 177, 10.1126/science.3798106

van de Vijver, 1987, Amplification of the neu (c-erbB-2) oncogene in human mammary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene, Mol Cell Biol, 7, 2019, 10.1128/MCB.7.5.2019

Ali, 1988, Amplification of c-erbB-2 and aggressive human breast tumors, Science, 240, 1795, 10.1126/science.3289120

Slamon, 1989, Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer, Science, 244, 707, 10.1126/science.2470152

Zellinger, 1989, HER-2 amplification, steroid receptors and epidermal growth factor receptor in primary breast cancer, Oncogene, 4, 109

Andane, 1989, Proto-oncogene amplification and human breast tumor phenotype, Oncogene, 4, 1389

Garcia, 1989, Genetic alterations of c-myc, c-erbB-2, and c-Haras protooncogenes and clinical associations in human breast carcinomas, Cancer Res, 49, 6675

Tsuda, 1989, Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1int-2 and c-erbB2/ear-1, Cancer Res, 49, 3104

Zhou, 1989, Proto-oncogene abonormalities in human breast cancer: c-erbB-2 amplification does not correlate with recurrence of disease, Oncogene, 4, 105

Tsuda, 1990, Correlation between histologic grade of malignancy and copy number of c-erbB-2 gene in breast carcinoma, Cancer, 65, 1794, 10.1002/1097-0142(19900415)65:8<1794::AID-CNCR2820650821>3.0.CO;2-Y

Borg, 1990, HER-2/neu amplification predicts poor survival in node-positive breast cancer, Cancer Res, 50, 4332

Tandon, 1989, HER-2/neu oncogene protein and prognosis in breast cancer, J Clin Oncol, 7, 1120, 10.1200/JCO.1989.7.8.1120

van de Vijver, 1988, neu-Protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer, N Engl J Med, 319, 1239, 10.1056/NEJM198811103191902

Barnes, 1988, An immunohistochemical evaluation of c-erbB-2 expression in human breast carcinoma, Br J Cancer, 58, 448, 10.1038/bjc.1988.238

Gusterson, 1988, c-erbB-2 expression in benign and malignant breast disease, Br J Cancer, 58, 453, 10.1038/bjc.1988.239

Gusterson, 1988, Immunohistochemical distribution of c-erbB-2 in infiltrating and in situ breast cancer, Int J Cancer, 42, 842, 10.1002/ijc.2910420608

Paik, 1990, Pathological findings from the national surgical adjuvant breast project (protocol B-06): Prognostic significance of erbB-2 protein overexpression in primary breast cancer, J Clin Oncol, 8, 103, 10.1200/JCO.1990.8.1.103

McCann, 1990, c-erbB-2 oncoprotein expression in primary human tumors, Cancer, 65, 88, 10.1002/1097-0142(19900101)65:1<88::AID-CNCR2820650119>3.0.CO;2-Z

Marx, 1990, c-erbB-2 expression in correlation to other biological parameters of breast cancer, J Cancer Res Clin Oncol, 116, 15, 10.1007/BF01612634

Page, 1987

Mansour, 1989, Efficacy of adjuvant chemotherapy in high-risk node-negative breast cancer, N Engl J Med, 320, 485, 10.1056/NEJM198902233200803

Fisher, 1980, Histologic grading of breast cancer, 239

Molina, 1990, Her-2/neu oncoprotein in breast cancer. A comparison of immunohistochemical and Western blot techniques, 31, 170

Allred, 1992, HER-2/neu in node-negative breast cancer. Prognostic significance of overexpression influenced by presence of in situ carcinoma, J Clin Oncol, 10, 599, 10.1200/JCO.1992.10.4.599

Muller, 1988, Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene, Cell, 54, 105, 10.1016/0092-8674(88)90184-5

Morson, 1984, The evolution of colorectal carcinoma, Clin Radiol, 35, 425, 10.1016/S0009-9260(84)80033-1

Narod, 1991, Dysplasia and the natural history of cervical cancer, Eur J Cancer, 27, 11, 10.1016/0277-5379(91)90022-6

Page, 1985, Atypical hyperplastic lesions of the female breast. A long-term follow-up study, Cancer, 55, 2698, 10.1002/1097-0142(19850601)55:11<2698::AID-CNCR2820551127>3.0.CO;2-A

Page, 1990, Anatomic markers of human premalignancy and risk of breast cancer, Cancer, 66, 1326, 10.1002/1097-0142(19900915)66:14+<1326::AID-CNCR2820661405>3.0.CO;2-P

Connolly, 1991, Benign breast disease and risk of subsequent breast cancer: The experience in the nurse's health study, Mod Pathol, 4, 10A

Kintanar, 1991, Further delineation of patterns of atypical ductal hyperplasia: An analysis of ADH patterns associated with intraductal and invasive breast carcinoma, Mod Pathol, 4, 12A

De Potter, 1989, The expression of the neu oncogene product in breast lesions and in normal fetal and adult human tissues, Histopathology, 15, 351, 10.1111/j.1365-2559.1989.tb01587.x

Lodato, 1990, Immunohistochemical evaluation of c-erbB-2 oncogene expression in ductal carcinoma in-situ and atypical ductal hyperplasia of the breast, Mod Pathol, 3, 449

Cardiff, 1988, Cellular and molecular aspects of neoplastic progression in the mammary gland, Eur J Cancer Clin Oncol, 24, 15, 10.1016/0277-5379(88)90171-X

Wright, 1989, Expression of c-erbB-2 oncoprotein: A prognostic indicator in human breast cancer, Cancer Res, 49, 2087

Barnes, 1988, An immunohistochemical evaluation of c-erbB-2 expression in human breast carcinoma, Br J Cancer, 58, 448, 10.1038/bjc.1988.238

Heintz, 1990, Amplification of the c-erbB-2 oncogene and prognosis of breast adenocarcinoma, Arch Pathol Lab Med, 114, 160

Anbazaghan R, Gelber RD, Bettelheim R, et al: Association of c-erbB-2 expression and S-phase fraction in the prognosis of node positive breast cancer. Ann Oncol (in press)

O'Reilly, 1991, The relationship between c-erbB-2 expression, S-phase fraction and prognosis in breast cancer, Br J Cancer, 63, 444, 10.1038/bjc.1991.102

Borg, 1991, ERBB2 amplification in breast cancer with high rate of proliferation, Oncogene, 6, 137

Kommoss, 1990, In situ distribution of oncogene products and growth factor receptors in breast carcinoma: c-erbB-2 oncoprotein, EGFR and PDGFR-b-subunit, Mol Cell Probes, 4, 11, 10.1016/0890-8508(90)90035-X