Optimization of ultrasound-assisted, microwave-assisted and Soxhlet extraction of bioactive compounds from Lagenaria siceraria: A comparative analysis

Ahmed, 2014, Phenolic and flavonoid contents and anti-oxidative potential of epicarp and mesocarp of Lagenaria siceraria fruit: a comparative study, Asian Pac J Trop Med, 7, S249, 10.1016/S1995-7645(14)60241-8

Ahmed, 2016, Cooking effect on anti-oxidative and alpha-amylase inhibitory potential of aqueous extract of Lagenaria siceraria fruit and its nutritional properties, Free Radic. Antioxid., 6, 44, 10.5530/fra.2016.1.5

Ahmed, 2017, Chemical constituents of Lagenaria siceraria mesocarp and its xanthine oxidase and alpha-amylase inhibitory activities, Int. J. Fruit Sci., 17, 310, 10.1080/15538362.2017.1315628

Ahmed, 2019, Hepatoprotective, anti-hemolytic, and anti-radical properties of cold-pressed, no-solvent, extract of bottle gourd fruit, Int. J. Veg. Sci., 25, 330, 10.1080/19315260.2018.1513963

Atique, 2018, Solvents for extraction of antidiabetic, iron chelating, and antioxidative properties from Bottle Gourd fruit, Int. J. Veg. Sci., 24, 212, 10.1080/19315260.2017.1409304

Biela, 2020, Antioxidant action of deprotonated flavonoids: thermodynamics of sequential proton-loss electron-transfer, Phytochemistry, 180, 10.1016/j.phytochem.2020.112528

Chaudhery, 2014, Study of bioactivities of lipid content of fresh Lagenaria siceraria seeds pulp and identification of its chemical constituents, J. Med. Plant Res., 8, 1014, 10.5897/JMPR2014.5484

Chemat, 2004, Comparison of conventional and ultrasound-assisted extraction of carvone and limonene from caraway seeds, Flavour Fragr. J., 19, 188, 10.1002/ffj.1339

Chen, 2021, The role of oat nutrients in the immune system: a narrative review, Nutrients, 13, 1048, 10.3390/nu13041048

da Rocha, 2020, Microwave-assisted extraction and ultrasound-assisted extraction of bioactive compounds from grape pomace, Int. J. Food Eng., 16

Dar, 2014, Comparative analysis of antimicrobial potential of peel and mesocarp of Lagenaria siceraria fruit extracts in various solvents against clinically important pathogens, Pharmacology, 3, 100

Das, 2020, Effects of microwave combined with ultrasound treatment on the pasteurization and nutritional properties of bottle gourd (lagenaria siceraria) juice, J. Food Process. Preserv., 44, 14904, 10.1111/jfpp.14904

De Castro, 2010, Soxhlet extraction: past and present panacea, J. Chromatogr. A, 1217, 2383, 10.1016/j.chroma.2009.11.027

Dobrinčić, 2020, Comparison of different extraction methods for the recovery of olive leaves polyphenols, Processes, 8, 1008, 10.3390/pr8091008

Enioutina, 2020, How can we improve the safe use of herbal medicine and other natural products? A clinical pharmacologist mission, Expert. Rev. Clin. Pharmacol., 13, 935, 10.1080/17512433.2020.1803739

Eskilsson, 2000, Analytical-scale microwave-assisted extraction, J. Chromatogr. A, 902, 227, 10.1016/S0021-9673(00)00921-3

Ferdaus, M.J., Ferdous, Z., Sara, R.J., Mahin, M.G.,Faruque, M.O., 2020. Total antioxidants activity and proximate analysis of selected fruits and vegetables in Jashore Region, Bangladesh. Curr. Res. Nutr. Food Sci. 8, 785–797. doi:10.12944/CRNFSJ.8.3.11.

Ghafoor, 2009, Optimization of ultrasound-assisted extraction of phenolic compounds, antioxidants, and anthocyanins from grape (Vitis vinifera) seeds, J. Agric. Food Chem., 57, 4988, 10.1021/jf9001439

Ghribia, L., Ghouilaa, H., Omrib, A., Besbesb, M., Janneta, H.B., 2014. Antioxidant and anti–acetylcholinesterase activities of extracts and secondary metabolites from Acacia cyanophylla. Asian Pac. J. Trop. Biomed. 4, S417–S423. doi:10.12980/APJTB.4.2014C1038.

Ghule, 2007, Diuretic activity of Lagenaria siceraria fruit extracts in rats, Indian J. Pharm. Sci., 69, 817, 10.4103/0250-474X.39441

Huyut, 2017, Antioxidant and antiradical properties of selected flavonoids and phenolic compounds, Biochem. Res. Int., 2017, 1, 10.1155/2017/7616791

Juee, 2020, Calabash (Lagenaria siceraria) potency to ameliorate hyperglycemia and oxidative stress in diabetes, J. Funct. Foods, 66, 103821, 10.1016/j.jff.2020.103821

Kaufmann, 2002, Recent extraction techniques for natural products: microwave-assisted extraction and pressurised solvent extraction, Phytochem. Anal., 13, 105, 10.1002/pca.631

Kronenberg, 2002, Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials, Ann. Intern. Med., 137, 805, 10.7326/0003-4819-137-10-200211190-00009

Kumar, 2012, Phytochemical, ethnobotanical and pharmacological profile of Lagenaria siceraria:-a review, J. Pharmacogn. Phytochem., 1, 24

Lampakis, 2021, Technologies and extraction methods of polyphenolic compounds derived from pomegranate (punica granatum) peels. A mini review, Processes, 9, 236, 10.3390/pr9020236

Louli, 2004, Recovery of phenolic antioxidants from wine industry by-products, Bioresour. Technol., 92, 201, 10.1016/j.biortech.2003.06.002

Lovrić, V., Putnik, P., Kovačević, D.B., Jukić, M., Dragović-Uzelac, V., 2017. Effect of microwave-assisted extraction on the phenolic compounds and antioxidant capacity of blackthorn flowers. Food Technol. Biotechnol. 55(2), 243–250. doi:10.17113/ftb.55.02.17.4687.

Maqsood, 2017, Lipase inhibitory activity of Lagenaria siceraria fruit as a strategy to treat obesity, Asian Pac J Trop Med, 10, 305, 10.1016/j.apjtm.2017.03.010

Martín, 2021, Impact of dietary flavanols on microbiota, immunity and inflammation in metabolic diseases, Nutrients, 13, 850, 10.3390/nu13030850

Mehany, 2021, Polyphenols as promising biologically active substances for preventing sars-cov-2: a review with research evidence and underlying mechanisms, Food Biosci., 40, 100891, 10.1016/j.fbio.2021.100891

Mohale, D., Dewani, A., Saoji, A., Khadse, C., 2008. Antihyperlipidemic activity of isolated constituents from the fruits of Lagenaria siceraria in albino rats. Int. J. Green Pharm. 2(2). DOI: 10.22377/ijgp.v2i2.39.

Naviglio, 2019, Rapid Solid-Liquid Dynamic Extraction (RSLDE): a powerful and greener alternative to the latest solid-liquid extraction techniques, Foods, 8, 245, 10.3390/foods8070245

Nayak, 2015, Comparison of microwave, ultrasound and accelerated-assisted solvent extraction for recovery of polyphenols from Citrus sinensis peels, Food Chem., 187, 507, 10.1016/j.foodchem.2015.04.081

Rahman, 2003, Bottle gourd (Lagenaria siceraria) a vegetable for good health, Nat. Prod. Rad., 2, 249

Rates, 2001, Plants as source of drugs, Toxicon, 39, 603, 10.1016/S0041-0101(00)00154-9

Saha, 2011, Antihyperglycemic activity of Lagenaria siceraria aerial parts on streptozotocin induced diabetes in rats, Diabetol. Croat., 40, 49

Sharma, 2015, Temperature-dependent studies on the total phenolics, flavonoids, antioxidant activities, and sugar content in six onion varieties, J. Food Drug Anal., 23, 243, 10.1016/j.jfda.2014.10.005

Sorokina, 2020, Review on natural products databases: where to find data in 2020, J. Cheminform., 12, 1, 10.1186/s13321-020-00424-9

Touiti, 2021, Overview on pharmacovigilance of nephrotoxic herbal medicines used worldwide, Clin. Phytosci., 7, 1, 10.1186/s40816-021-00248-6

Trujillo-Mayol, 2019, Improvement of the polyphenol extraction from avocado peel by assisted ultrasound and microwaves, J. Food Process Eng., 42, 13197, 10.1111/jfpe.13197

Tungmunnithum, 2018, Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: an overview, Medicines, 5, 93, 10.3390/medicines5030093

Upaganlawar, 2011, Cardioprotective effects of Lagenaria siceraria fruit juice on isoproterenol-induced myocardial infarction in wistar rats: a biochemical and histoarchitecture study, J. Young Pharm., 3, 297, 10.4103/0975-1483.90241

Veeresham, 2012, Natural products derived from plants as a source of drugs, J. Adv. Pharm. Technol. Res., 3, 200, 10.4103/2231-4040.104709

Yetişir, H., Şakar, M., Serçe, S., 2008. Collection and morphological characterization of Lagenaria siceraria germplasm from the Mediterranean region of Turkey. Genet. Resour. Crop Evol. 55(8), 1257–1266. doi:https://doi.org/10.1007/s10722-008-9325-y.

Zhang, 2018, Techniques for extraction and isolation of natural products: a comprehensive review, Chin. Med., 13, 20, 10.1186/s13020-018-0177-x