Op metastasen gerichte behandeling van prostaatcarcinoom

Tijdschrift voor Urologie - Tập 9 Số 6-7 - Trang 108-116 - 2019
G.H.J.M. Leyten1, Inge M. van Oort2, Andries M. Bergman3
1afdeling Urologie, Nederlands Kanker Instituut, Amsterdam, Nederland
2afdeling Urologie, Radboud Universiteit Medisch Centrum, Nijmegen, Nederland
3afdeling Medische oncologie, Nederlands Kanker Instituut, Amsterdam, Nederland

Tóm tắt

Samenvatting Het aantal behandelmogelijkheden voor gemetastaseerd prostaatkanker en castratieresistent prostaatkanker is het laatste decennium belangrijk toegenomen. Van abirateron, enzalutamide, cabazitaxel en radium-223 is reeds een overlevingswinst aangetoond. In dit overzichtsartikel zullen we de huidige behandelmogelijkheden en de nieuwste ontwikkelingen op het gebied van gemetastaseerd prostaatcarcinoom bespreken, onder andere nieuwe indicaties zoals ‘upfront’ abirateron, en mogelijke toekomstige behandelingen zoals 177Lu-PSMA-617 behandeling, en de ontwikkelingen op het gebied van immunotherapie. Ook zullen wij de huidige gegevens over de meerwaarde van behandelen van de patiënt met oligometastasen bespreken.

Từ khóa


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