Ocular hemodynamic changes in patients with high‐grade carotid occlusive disease and development of chronic ocular ischaemia

Wiley - Tập 73 Số 1 - Trang 66-71 - 1995
Emı́lia Kerty1, Ivar Hörven2
1Departments of Neurology, Rikshospitalet, University of Oslo, Norway
2Departments of Ophthalmology, Rikshospitalet, University of Oslo, Norway

Tóm tắt

ABSTRACT Ophthalmic artery blood flow pattern and the pulsatile ocular blood volume changes in patients with hemodynamically significant carotid occlusive disease are described. Using transorbital Doppler ultrasonography and dynamic tonometry 45 patients with high‐grade internal carotid artery stenosis or occlusion and 15 healthy controls were examined. The measurements were performed under baseline conditions and 30 min after 1 gi.v. acetazolamide administration. The velocity in the ophthalmic artery was significantly lower in patients compared with controls. Pulsatile ocular blood volume was also lower in patients than in controls under baseline conditions, and a further reduction was found after acetazolamide, despite the significant decrease of intraocular pressure. A different reaction was observed in eyes with chronic ocular ischaemia.

Từ khóa


Tài liệu tham khảo

10.1111/j.1600-0404.1988.tb05939.x

10.3171/jns.1982.57.6.0769

Alm A, 1992, Adler's physiology of the eye, 214

10.1016/0014-4835(73)90185-1

Duker J S, 1991, Foundations of clinical ophthalmology, 22

Fish P, 1990, Physics and instrumentation of diagnostic medical ultrasound, 218

10.1177/00359157740676P113

10.1016/S0161-6420(92)31784-1

10.1111/j.1755-3768.1968.tb05914.x

10.1111/j.1755-3768.1970.tb06570.x

10.1111/j.1755-3768.1978.tb01370.x

10.1161/01.STR.24.8.1196

Johnson P C, 1964, Origin, localization and homeostatic significance of autoregulation in the intestine, Circ Res (Supp), 15, 225

10.1111/j.1755-3768.1994.tb02786.x

Kerty E, 1995, Ocular hemodynamic changes in patients with high‐grade carotid occlusive disease and development of chronic ocular ischaemia. II. Clinical findings. Acta Ophthalmol, Scand., 73, 72

10.3171/jns.1985.63.6.0890

Lindegaard K‐F, 1992, Transcranial Doppler, 79

Planiol T, 1973, La circulation carotidienne et cérébrale. Progrés réalises dans l'étude par les methodes physiques externes, Nouv Presse Med, 37, 2451

Riva C E, 1985, Blood velocity and volumetric flow rate in human retinal vessels, Invest Ophthalmol Vis Sci, 26, 1124

10.1136/bjo.77.1.22

10.1017/S0317167100045510

10.1136/jnnp.47.12.1307

10.1161/01.STR.17.5.916

10.1161/01.STR.10.3.326