New Insights Into Merkel Cell Carcinoma

Toker, 1972, Trabecular carcinoma of the skin, Arch Derm, 105, 107, 10.1001/archderm.1972.01620040075020

Rywlin, 1982, Malignant Merkel-cell tumor is a more accurate description than trabecular carcinoma, Am J Dermatopathol, 4, 513, 10.1097/00000372-198212000-00007

Tang, 1977, Trabecular carcinoma of the skin an ultrastructural study, Cancer, 42, 2311, 10.1002/1097-0142(197811)42:5<2311::AID-CNCR2820420531>3.0.CO;2-L

Toker, 1982, Trabecular carcinoma of the skin a question of title, Am J Dermatopathol, 4, 497, 10.1097/00000372-198212000-00003

Halata, 2003, Friedrich Sigmund Merkel and his “Merkel cell” morphology, development and physiology: review and new results, Anat Rec, 271, 225, 10.1002/ar.a.10029

Foschini, 2000, Divergent differentiation in endocrine and non-endocrine tumors of the skin, Semin Diagn Pathol, 17, 162

LeBoit, 1992, Pagetoid intraepidermal spread in Merkel cell (Primary neuroendocrine) carcinoma of the skin, Am J Surg Pathol, 16, 584, 10.1097/00000478-199206000-00006

Brown, 2000, Intraepidermal Merkel cell carcinoma with no dermal involvement, Am J Dermatopathol, 22, 65, 10.1097/00000372-200002000-00013

Smith, 1993, Neuroendocrine (Merkel cell) carcinoma with an intraepidermal component, Am J Dermatopathol, 15, 528, 10.1097/00000372-199312000-00002

Skelton, 1997, Merkel cell carcinoma: analysis of clinical, histologic and immunohistologic features of 132 cases with relation to survival, J Am Acad Dermatol, 37, 734, 10.1016/S0190-9622(97)70110-5

Rocamora, 1987, Epidermotropic primary neuroendocrine (Merkel cell) carcinoma of the skin with Pautrier-like microabcesses, J Am Acad Dermatol, 16, 1163, 10.1016/S0190-9622(87)70151-0

Gilman, 1991, Epidermotropic neuroendocrine carcinoma. Immunohistochemical differentiation from simulators, including malignant melanoma, J Cutan Pathol, 18, 120, 10.1111/j.1600-0560.1991.tb00139.x

Yamamoto, 1993, A combined occurrence of neuroendocrine carcinoma of the skin and a benign appendageal neoplasm, J Cutan Pathol, 20, 173, 10.1111/j.1600-0560.1993.tb00237.x

Collina, 1997, Combined neuroendocrine carcinoma of the skin (Merkel cell) and trichilemmal cyst, Am J Dermatopathol, 19, 545, 10.1097/00000372-199710000-00111

Perse, 1987, Trabecular (Merkel cell) carcinoma arising in the wall of an epidermal cyst, Am J Dermatopathol, 9, 423, 10.1097/00000372-198710000-00009

Walsh, 2001, Primary neuroendocrine (Merkel cell) carcinoma of the skin: morphologic diversity and implications thereof, Hum Pathol, 32, 680, 10.1053/hupa.2001.25904

Hwang, 2008, Merkel cell carcinoma with squamous and sarcomatous differentiation, J Cutan Pathol, 35, 955, 10.1111/j.1600-0560.2007.00917.x

Isimbaldi, 1993, Tripartitie differentiation (squamous, glandular and melanocytic) of a primary cutaneous neuroendocrine carcinoma, Am J Dermatopathol, 15, 260, 10.1097/00000372-199306000-00012

Saeb-Lima, 2008, Merkel cell carcinoma with eccrine differentiation: a clinicopathologic study of 7 cases, Ann Diagn Pathol, 12, 410, 10.1016/j.anndiagpath.2008.07.001

Cooper, 2000, Merkel cell tumor with leiomyosarcomatous differentiation, Histopathology, 36, 540, 10.1046/j.1365-2559.2000.00896.x

Eusebi, 2000, Small cell neuroendocrine carcinoma with skeletal muscle differentiation. Report of three cases, Am J Surg Pathol, 24, 223, 10.1097/00000478-200002000-00008

Tan, 2008, Merkel cell carcinoma with fibrosarcomatous differentiation, Pathology, 40, 314, 10.1080/00313020701813685

Albores-Saavedra, 2010, Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study, J Cutan Pathol, 37, 20, 10.1111/j.1600-0560.2009.01370.x

Heath, 2008, Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the “AEIOU” features, J Am Acad Dermatol, 58, 375, 10.1016/j.jaad.2007.11.020

Penn, 1999, Merkel's cell carcinoma in organ recipients: report of 41 cases, Transplantation, 68, 1717, 10.1097/00007890-199912150-00015

Feng, 2008, Clonal integration of a polyomavirus in human Merkel cell carcinoma, Science, 319, 1096, 10.1126/science.1152586

Busam, 2009, Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas, Am J Surg Pathol, 33, 1378, 10.1097/PAS.0b013e3181aa30a5

Andres, 2010, Prevalence of Merkel MCPyV in Merkel cell carcinoma and non-MCC tumors, J Cutan Pathol, 37, 28, 10.1111/j.1600-0560.2009.01352.x

Popp, 2002, UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas, Int J Cancer, 99, 352, 10.1002/ijc.10321

Lunder, 1998, Merkel-cell carcinomas in patients treated with methoxsalen and ultraviolet A radiation, N Engl J Med, 339, 1247, 10.1056/NEJM199810223391715

Bobos, 2006, Immunohistochemical distinction between merkel cell carcinoma and small cell carcinoma of the lung, Am J Dermatopathol, 28, 99, 10.1097/01.dad.0000183701.67366.c7

Chu, 2000, Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases, Mod Pathol, 9, 962, 10.1038/modpathol.3880175

Jensen, 2000, Cytokeratin staining in Merkel cell carcinoma: an immunohistochemical study of cytokeratins 5/6, 7, 17, and 20, Appl Immunohistochem Mol Morphol, 8, 310, 10.1097/00022744-200012000-00008

Calder, 2007, A case series and immunophenotypic analysis of CK20−/CK7+ primary neuroendocrine carcinoma of the skin, J Cutan Pathol, 34, 918, 10.1111/j.1600-0560.2007.00759.x

Hanly, 2000, Analysis of thyroid transcription factor-1 and cytokeratin 20 separates merkel cell carcinoma from small cell carcinoma of the lung, J Cutan Pathol, 27, 118, 10.1034/j.1600-0560.2000.027003118.x

Ralston, 2008, MASH1: a useful marker in differentiating pulmonary small cell carcinoma from merkel cell carcinoma, Mod Pathol, 21, 1357, 10.1038/modpathol.2008.118

Su, 2002, CD117 (KIT receptor) expression in Merkel cell carcinoma, Am J Dermatopathol, 24, 289, 10.1097/00000372-200208000-00001

Nicholson, 2000, CD99 and cytokeratin-20 in small-cell and basaloid tumors of the skin, Appl Immunohistochem Mol Morphol, 8, 37, 10.1097/00129039-200003000-00006

Buresh, 2008, Reactivity with TdT in Merkel cell carcinoma: a potential diagnostic pitfall, Am J Clin Pathol, 129, 894, 10.1309/R494HQ9VRDJWDY30

Asioli, 2007, p63 expression as a new prognostic marker in Merkel cell carcinoma, Cancer, 110, 640, 10.1002/cncr.22828

Goldberg, 2007, Prognostic value of tumor thickness in patients with Merkel cell carcinoma, J Surg Pathol, 95, 618

Andea, 2008, Merkel cell carcinoma: histologic features and prognosis, Cancer, 113, 2549, 10.1002/cncr.23874

Llombart, 2005, Clinicopathologic and immunohistochemical analysis of 20 cases of Merkel cell carcinoma in search of prognostic markers, Histopathol, 46, 622, 10.1111/j.1365-2559.2005.02158.x

Mott, 2004, Merkel cell carcinoma: a clinicopathologic study with prognostic implications, J Cutan Pathol, 31, 217, 10.1111/j.0303-6987.2004.00149.x

Allen, 2005, Merkel cell carcinoma: prognosis and treatment of patients from a single institution, J Clin Oncol, 23, 2300, 10.1200/JCO.2005.02.329

Allen, 1999, The surgical management of Merkel cell carcinoma, Ann Surg, 229, 97, 10.1097/00000658-199901000-00013

Edge, 2009, AJCC Cancer Staging Manual. 7th ed

Beer, 2008, Mast cells have prognostic value in Merkel cell carcinoma, Am J Dermatopathol, 30, 27, 10.1097/DAD.0b013e31815c932a

Ng, 2008, Vascular density has prognostic value in Merkel cell carcinoma, Am J Dermatopathol, 30, 442, 10.1097/DAD.0b013e318172364d

Kim, 2008, Nuclear expression of survivin portends a poor prognosis in Merkel cell carcinoma, Mod Pathol, 21, 764, 10.1038/modpathol.2008.61

Fernandez-Figueras, 2007, Expression profiles associated with aggressive behavior in Merkel cell carcinoma, Mod Pathol, 20, 90, 10.1038/modpathol.3800717

Brunner, 2008, Expression of VEGF-A/C, VEGF-R2, PDGF-alpha/beta, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma, Mod Pathol, 21, 876, 10.1038/modpathol.2008.63

Gupta, 2006, Sentinel lymph node biopsy for evaluation and treatment of patients with Merkel cell carcinoma, Arch Dermatol, 142, 685, 10.1001/archderm.142.6.685

Stokes, 2009, Patients with Merkel cell carcinoma tumors <1.0 cm in diameter are unlikely to harbor regional lymph node metastasis, J Clin Oncol, 27, 3772, 10.1200/JCO.2008.20.8272

Kokoska, 1997, Early aggressive treatment for Merkel cell carcinoma improves outcome, Am J Surg, 174, 688, 10.1016/S0002-9610(97)00193-1

Gillenwater, 2001, Merkel cell carcinoma of the head and neck: effect of surgical excision and radiation on recurrence and survival, Arch Otolaryngol Head Neck Surg, 127, 149, 10.1001/archotol.127.2.149