Neurosteroids: Biosynthesis, metabolism and function of pregnenolone and dehydroepiandrosterone in the brain

Naftolin, 1975, The formation of estrogens by central neuroendocrine tissues, Recent Prog. Horn. Res., 31, 295 Celotti, 1979, Metabolism of sex steroids in the central nervous system, Vol. 1, 41 Corpéchot, 1981, Characterization and measurement of dehydroepiandrosterone sulfate in rat brain, 78, 4704 Corpéchot, 1981, Déhydroépiandrostérone libre et sulfo-conjuguée dans le cerveau de souris dysmyéliniques, C.R. Acad. Sci. Paris, 292, 231 Corpéchot, 1983, Pregnenolone and its sulfate ester in the rat brain, Brain Res., 270, 119, 10.1016/0006-8993(83)90797-7 Jo, 1989, Pregnenolone, dehydroepiandrosteron, and their sulfate and fatty acid esters in the rat brain, Steroids, 54, 287, 10.1016/0039-128X(89)90003-2 Lacroix, 1987, Simultaneous radioimmunoassay of progesterone, androst-4-enedione, pregnenolone, dehydroepiendrosterone and 17β-hydroxy-progesterone in specific regions of human brain, J. Steroid Biochem., 28, 317, 10.1016/0022-4731(87)91025-9 Lanthier, 1986, Sex steroids and 5-ene-3β-hydroxysteroids in specific regions of the human brain and cranial nerves, J. Steroid Biochem., 25, 445, 10.1016/0022-4731(86)90259-1 Robel, 1987, Neurosteroids: 3β-hydroxy-Δ5-derivatives in rat and monkey brain, J. Steroid Biochem., 27, 649, 10.1016/0022-4731(87)90133-6 Synguelakis, 1985, Evolution circadienne de Δ5-3β-hydroxystéroïdes et de glucocorticoïdes dans le plasma et le cerveau de rat, C.R. Acad. Sci. Paris, 301, 823 Robel, 1986, Neuro-steroids: 3β-hydroxy-Δ5-derivatives in the rat brain, 367 Kishimoto, 1973, Fatty acid esters of testosterone in rat brain: identification distribution and some properties of enzymes which synthetize and hydrolyze the ester, Archs Biochem. Biophys., 159, 528, 10.1016/0003-9861(73)90485-2 Pahuja, 1989, A comparison of the fatty acid esters of estradiol and corticosterone synthesized by tissues of the rat, J. Biol. Chem., 264, 3216, 10.1016/S0021-9258(18)94054-8 Martyn, 1988, Properties of fatty acyl-coenzyme A: estradiol-17β acyltransferase in bovine placental microsomes, Molec. Cell. Endocr., 60, 7, 10.1016/0303-7207(88)90114-1 Oftebro, 1979, The presence of an adrenodoxin-like ferredoxin and cytochrome P-450 in brain mitochondria, J. Biol. Chem., 254, 4331, 10.1016/S0021-9258(17)30009-1 DuBois, 1981, Induction of synthesis of cholesterol side chain cleavage cytochrome P-450 by adrenocorticotropin in cultured bovine adrenocortical cells, J. Biol. Chem., 256, 7000, 10.1016/S0021-9258(19)69090-3 Le Goascogne, 1987, Neurosteroids: cytochrome P450soc in rat brain, Science, 237, 1212, 10.1126/science.3306919 Le Goascogne, 1989, Cell specific variations and hormonal regulation of immunoreactive cytochrome P450soc in the rat ovary, J. Reprod. Fert., 85, 61072, 10.1530/jrf.0.0850061 Hu, 1989, Neurostéroïdes: biosynthèse et métabolisme de la prégnènolone dans les oligodendrocytes du cerveau de rat Warner, 1989, Endocrine regulation of cytochrome P-450 in the rat brain and pituitary gland, J. Endocr., 122, 341, 10.1677/joe.0.1220341 Hu, 1987, Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone, 84, 8215 Jung-Testas, 1989, Neurosteroids: biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells, Endocrinology, 125, 2083, 10.1210/endo-125-4-2083 Banzal, 1985, Developmental expression of 2′,3′ cyclic nucleotide 3′ phosphodiesterase in dissociated fetal rat brain cultures and rat brain, J. Neurosci. Res., 14, 21, 10.1002/jnr.490140103 Jung-Testas, 1989, Localisation immunocytochimique du cytochrome P-450soc dans les oligodendrocytes de rat en culture, C. R. Acad. Sci. Paris, 308, 165 Aloisi, 1988, Differentiation of bipotential glial precursors in oligodendrocytes is promoted by interaction with type-1 astrocytes in cerebellar cultures, 85, 6167 Hall, 1985, Trophic stimulation of steroidogenesis: in search of the elusive trigger, Recent Prog. Horm. Res., 41, 1 Hu, 1989, Neurosteroids: steroidogenesis in primary cultures of rat glial cells after release of aminoglutethimide blockade, Biochem. Biophys. Res. Commun., 161, 917, 10.1016/0006-291X(89)92686-7 Darbeida, 1988, Glucocorticoid enhancement of glucorticoid production by cultured ovine adrenocortical cells, Biochim. Biophys. Acta, 272, 200, 10.1016/0167-4889(88)90118-8 Le Goascogne, 1989, The cholesterol side-chain cleavage complex in human brain white matter, J. Neuroendocr., 1, 153, 10.1111/j.1365-2826.1989.tb00095.x Weidenfeld, 1978, In vitro conversion of pregnenolone to progesterone by discrete brain areas of the male rat, J. Steroid Biochem., 13, 961, 10.1016/0022-4731(80)90171-5 Ficher, 1978, In vitro progesterone metabolism by selected brain areas, pituitary gland and testes of the adult male rat, J. Steroid Biochem., 9, 203, 10.1016/0022-4731(78)90150-4 Karavolas, 1988, Conversion of 17α-hydroxy-progesterone to 5α, 3α and 20α-reduced metabolites by female rat anterior pituitary and hypothalamus, Steroids, 51, 527, 10.1016/0039-128X(88)90049-9 Shinzawa, 1988, Relationship between zonal distribution of microsomal cytochrome P-450s (P-45017α,lyase and P-450C21) and steroidogenic activities in guinea-pig adrenal cortex, J. Endocr., 119, 191, 10.1677/joe.0.1190191 Adams, 1981, Estrogenic effects of physiological concentration of 5-androstene-3β,17β-diol and its metabolism in MCF7 human breast cancer cells, Cancer Res., 41, 4720 Poortman, 1975, Interactions of Δ5-androstene-3β,17β-diol with estradiol and dihydrotestosterone receptors in human myometrial and mammary cancer tissue, J. Clin. Endocr. Metab., 40, 373, 10.1210/jcem-40-3-373 Warner, 1989, Distribution and regulation of 5α-androstane-3β,17β-diol hydroxylase in the rat central nervous system, Endocrinology, 124, 2699, 10.1210/endo-124-6-2699 Baulieu, 1987, Neurosteroids: pregnenolone and dehydroepiandrosterone in the brain, Vol. 48, 89 Corpéchot, 1985, Neurosteroids: regulatory mechanism in male rat brain during heterosexual exposure, Steroids, 45, 229, 10.1016/0039-128X(85)90072-8 Lanthier, 1987, Effect of heterosexual olfactory and visual stimulation of 5-en-3β-hydroxysteroids and progesterone in the male rat brain, J. Steroid Biochem., 28, 697, 10.1016/0022-4731(87)90400-6 Haug, 1979, Effects of treatment with testosterone and estradiol on the attack by groups of gonadectomized male and female mice towards lactatcol2 intruders, Physiol. Behav., 23, 397, 10.1016/0031-9384(79)90385-8 Schlegel, 1985, Studies on the effects of dehydroepiandrosterone and its metabolites on attack by castrated mice on lactating intruders, Physiol. Behav., 34, 867, 10.1016/0031-9384(85)90005-8 Levitan, 1988, Structural and functional basis for GABAA receptor heterogeneity, Nature, 335, 76, 10.1038/335076a0 Olsen, 1982, Drug interaction at the GABA receptor-ionophore complex, A. Rev. Pharmac. Toxic., 22, 245, 10.1146/annurev.pa.22.040182.001333 Lambert, 1987, Actions of synthetic and endogenous steroids on the GABAA receptors, Trends Pharmac. Sci., 8, 224, 10.1016/0165-6147(87)90067-8 Majewska, 1986, Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor, Science, 232, 1004, 10.1126/science.2422758 Puia, 1990, Neurosteroids act on recombinant human GABAA receptors, Neuron, 4, 759, 10.1016/0896-6273(90)90202-Q Majewska, 1987, Pregnenolone-sulfate: an endogenous antagonist of the γ-amino butyric acid receptor complex in brain?, Brain Res., 404, 355, 10.1016/0006-8993(87)91394-1 Mienville, 1988, Pregnenolone sulfate and anionic currents Majewska, 1989, Pregnenolone sulfate antagonizes barbiturate-induced hypnosis, Biochem. Behav., 33, 701, 10.1016/0091-3057(89)90410-3 Jung-Testas, 1991, Estrogen-inducible progesterone receptor in primary cultures of rat glial cells, Exp. cell. Res., 193, 12, 10.1016/0014-4827(91)90532-Y Heyns, 1977, Prostatic binding protein. A steroid-binding protein secreted by rat prostate, Eur. J. Biochem., 78, 221, 10.1111/j.1432-1033.1977.tb11733.x Strott, 1977, A pregnenolone-binding protein in soluble fraction of guinea pig adrenal cortex, J. Biol. Chem., 252, 464, 10.1016/S0021-9258(17)32739-4 Lanthier, 1990, Pregnenolone binding sites in the rat olfactory bulb, J. Steroid Biochem., 35, 487, 10.1016/0022-4731(90)90258-T Baulieu, 1978, Steroid induced meiotic division in Xenopus laevis oocytes: surface and calcium, Nature, 275, 593, 10.1038/275593a0 Blondeau, 1984, Progesterone receptor characterized by photoaffinity labelling in the plasma membrane of Xenopus laevis oocytes, Biochem. J., 219, 785, 10.1042/bj2190785 Towle, 1983, Steroid binding to synaptic plasma membrane: differential binding of glucocorticoids and gonadal steroids, J. Steroid Biochem., 18, 135, 10.1016/0022-4731(83)90079-1 Melcangi, 1988, Testosterone 5α-reductase activity in the rat brain is highly concentrated in white matter structures and in purified myelin sheaths of axons, J. Steroid Biochem., 31, 173, 10.1016/0022-4731(88)90051-9