Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein
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Balcarek, 1985, Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family, Nucl. Acids Res., 13, 5527, 10.1093/nar/13.15.5527
Beaudet, 1992, Intragenic regulatory elements contribute to transcriptional control of the neurofilament light gene, Gene, 116, 205, 10.1016/0378-1119(92)90517-S
Berthold, 1978, Morphology of normal peripheral axons, 3
Bradford, 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72, 284, 10.1016/0003-2697(76)90527-3
Brady, 1993, Motor neuronsand neurofilaments in sickness and health, Cell, 73, 1, 10.1016/0092-8674(93)90151-F
Burnett, 1981, Western blotting. Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A, Anal Biochem., 112, 195, 10.1016/0003-2697(81)90281-5
Carden, 1985, The structure, biochemical properties, and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state, J. Biol. Chem., 260, 9805, 10.1016/S0021-9258(17)39307-9
Carden, 1986, 2,5Hexanedione neuropathy is associated with covalent crosslinking of neurofilament proteins, Neurochem. Pathol., 5, 15, 10.1007/BF03028034
Carden, 1987, Two-stage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns, J. Neurosci., 7, 3489, 10.1523/JNEUROSCI.07-11-03489.1987
Carden, 1987, Studies of neurofilaments that accumulate in proximal axons of rat intoxicated with β,β-iminodipropri-onitrile (IDPN), Neurochem. Pathol., 7, 189, 10.1007/BF03160180
Carpenter, 1968, Proximal enlargement in motor neuron diseases, Neurology, 18, 841, 10.1212/WNL.18.9.841
Cochard, 1984, Initial expression of neurofilaments and vimentin in the central and peripheral nervous system of the mouse embryo in vivo, J. Neurosci., 4, 2080, 10.1523/JNEUROSCI.04-08-02080.1984
Corbo, 1992, Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease, J. Neuropathol. Exp. Neurol., 51, 531, 10.1097/00005072-199209000-00008
Côté, 1993, Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis, Cell, 73, 35, 10.1016/0092-8674(93)90158-M
de Waegh, 1992, Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells, Cell, 68, 451, 10.1016/0092-8674(92)90183-D
Elder, 1992, Multiple nuclear factors interact with the promoter of the human neurofilament gene, Mol. Brain Res., 15, 99, 10.1016/0169-328X(92)90156-6
Elder, 1992, Novel DNA binding proteins participate in the regulation of human neurofilament gene expression, Mol. Brain Res., 15, 85, 10.1016/0169-328X(92)90155-5
Escurat, 1990, Differential expression of two neuronal intermediatefilament proteins, peripherin and the low-molecular-mass neurofilament protein (NF-L), during development of the rat, J. Neurosci., 10, 764, 10.1523/JNEUROSCI.10-03-00764.1990
Eyer, 1988, Influence of the phosphorylation state of neurofilament proteins on the interactions between purified filaments in vitro, Biochem. J., 252, 655, 10.1042/bj2520655
Fliegner, 1991, Cellular and molecular biology of neuronal intermediate filaments, Int. Rev. Cytol., 131, 109, 10.1016/S0074-7696(08)62018-5
Fliegner, 1990, The predicted amino acid sequence of a-internexin is that of a novel neuronal intermediate filament protein, EMBO J., 9, 749, 10.1002/j.1460-2075.1990.tb08169.x
Franke, 1987, Nuclear laminins and cytoplasmic intermediate filament proteins: a growing multigene family, Cell, 48, 3, 10.1016/0092-8674(87)90345-X
Friede, 1970, Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice, Anat. Rec., 167, 379, 10.1002/ar.1091670402
Geisler, 1983, Neurofilament architecture combines structural principles of intermediate filaments with carboxy-terminal extensions increasing in size between triplex proteins, EMBO J., 2, 1295, 10.1002/j.1460-2075.1983.tb01584.x
Geisler, 1984, Hybrid character of large neurofilament protein (NF-M): intermediate filament type sequences followed by a long acidic carboxy-terminal extension, EMBO J., 3, 2701, 10.1002/j.1460-2075.1984.tb02196.x
Geisler, 1985, Protein-chemical characterization of NF-H, the largest mammalian neurofilament component; intermediate filament-type sequences followed by a unique carboxy-terminal extension, EMBO J., 4, 57, 10.1002/j.1460-2075.1985.tb02317.x
Glicksman, 1985, Differential expression of the three neurofilament polypeptides, Ann. NY Acad. Sci., 455, 479, 10.1111/j.1749-6632.1985.tb50430.x
Goldman, 1986, Cytoskeletal protein abnormalities in neurodegenerative diseases, Ann Neurol., 19, 209, 10.1002/ana.410190302
Goldstein, 1987, Phosphorylation protects neurofilaments against proteolysis, J. Neuroimmunol., 14, 149, 10.1016/0165-5728(87)90049-X
Goldstein, 1988, mRNA levels of all three neurofilament proteins decline following nerve transection, Mol. Brain Res., 3, 287, 10.1016/0169-328X(88)90051-4
Gotow, 1992, Macromolecular structure of reassembled neurofilaments as revealed by the quick-freeze deep-etch mica method: difference between NF-M and NF-H subunits in their ability to form crossbridges, Eur. J. Cell. Biol., 58, 331
Griffin, 1980, Proximal axonopathies induced by toxic chemicals, 161
Griffin, 1978, Slow axonal transport of neurofilament proteins; impairment by ββ′-iminodiproprionitrileadministration, Science, 202, 633, 10.1126/science.81524
Hirokawa, 1982, Cross linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method, J. Cell Biol., 94, 129, 10.1083/jcb.94.1.129
Hirokawa, 1991, Molecular architecture and dynamics of the neuronal cytoskeleton, 5
Hirokawa, 1984, Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton, J. Cell Biol., 98, 1523, 10.1083/jcb.98.4.1523
Hisanaga, 1989, The effects of dephosphorylation on the structure of the projections of neurofilaments, J. Neurosci., 9, 959, 10.1523/JNEUROSCI.09-03-00959.1989
Hoffman, 1983, Slowing of the axonal transport of neurofilament proteins during development, J. Neurosci., 3, 1694, 10.1523/JNEUROSCI.03-08-01694.1983
Hoffman, 1984, Control of axonal caliber by neurofilament transport, J. Cell Biol., 99, 705, 10.1083/jcb.99.2.705
Hoffman, 1985, Slowing of neurofilament transport and the radial growth of developing nerve fibers, J. Neurosci., 5, 2920, 10.1523/JNEUROSCI.05-11-02920.1985
Hoffman, 1985, Changes in neurofilament transport coincide temporally with alterations in the caliber of axons in regenerating motor fibers, J. Cell Biol., 101, 1332, 10.1083/jcb.101.4.1332
Hoffman, 1987, Neurofilament gene expression: a major determinant of axonal caliber, 84, 3472
Julien, 1982, Multiple phosphorylation sites in mammalian neurofilament polypeptides, J. Biol. Chem., 257, 10467, 10.1016/S0021-9258(18)34041-9
Julien, 1986, Cloning and developmental expression of the murine neurofilament gene family, Mol. Brain Res., 1, 243, 10.1016/0169-328X(86)90030-6
Julien, 1987, Expression and assembly of a human neurofilament protein in transgenic mice provide a novel neuronal marking system, Genes Dev., 1, 1085, 10.1101/gad.1.10.1085
Julien, 1988, Sequence and structure of the mouse gene coding for the largest neurofilament subunit, Gene, 68, 307, 10.1016/0378-1119(88)90033-9
Kaplan, 1990, Alpha-internexin, a novel neuronal intermediate filament protein, precedes the low molecular weight neurofilament protein (NF-L) in the developing rat brain, J. Neurosci., 10, 2735, 10.1523/JNEUROSCI.10-08-02735.1990
Kelly, 1992, Schwann cells of the myelin-forming phenotype express neurofilament protein NF-M, J. Cell Biol., 118, 397, 10.1083/jcb.118.2.397
Laemmli, 1970, Cleavage of structural proteins during assembly of the head of bacteriophage T4, Nature, 227, 680, 10.1038/227680a0
Langley, 1976, β-Galactosidase a complementation: properties of the complemented enzyme and mechanism of the complementation reaction, Biochem., 15, 4866, 10.1021/bi00667a018
Lasek, 1983, Molecular biology of neuronal geometry: expression of neurofilament genes influences axonal diameter, 18, 731
Lee, 1987, Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NFH and NFM) and demonstrate their existence in the normal nervous system of adult rats, J. Neurosci., 7, 3474, 10.1523/JNEUROSCI.07-11-03474.1987
Lee, 1988, Identification of the major multiphosphorylation site in mammalian neurofilaments., 85, 1998
Le Mouellic, 1990, Targeted replacement of the homeobox gene Hox-3.1 by the Escherichia coli IacZ in mouse chimeric embryos, Proc. Natl. Acad. Sci. USA, 87, 4712, 10.1073/pnas.87.12.4712
Lendahl, 1990, CNS stem cells express a new class of intermediate filament protein, Cell, 60, 585, 10.1016/0092-8674(90)90662-X
Leterrier, 1987, Properties of highly viscous gels formed by neurofilaments in vitro. A possible consequence of a specific inter-filament cross-bridging, Biochem. J., 245, 93, 10.1042/bj2450093
Liem, 1993, Molecular biology of neuronal intermediate filaments, Curr. Opin. Cell Biol., 5, 12, 10.1016/S0955-0674(05)80003-1
McLean, 1974, Periodate-lysine-paraformaldehyde fixative. A new fixative for immunoelectron microscopy, J. Histochem. Cytochem., 22, 1077, 10.1177/22.12.1077
Mitchison, 1988, Cytoskeletal dynamics in nerve growth, Neuron, 1, 761, 10.1016/0896-6273(88)90124-9
Monaco, 1989, Experimental increase of neurofilament transport rate: decreases in neurofilament number and in axon diameter, J. Neuropathol. Exp. Neurol., 48, 23, 10.1097/00005072-198901000-00003
Monteiro, 1990, Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axons without affecting caliber, J. Cell Biol., 111, 1543, 10.1083/jcb.111.4.1543
Muma, 1990, Alterations in levels of mRNAs coding for neurofilament protein subunits during regeneration, Exp. Neurol., 107, 230, 10.1016/0014-4886(90)90140-N
Oblinger, 1988, Axotomy induced alterations in the synthesis and transport of neurofilaments and microtubules in dorsal root ganglion cells, J. Neurosci., 8, 1747, 10.1523/JNEUROSCI.08-05-01747.1988
Osamu, 1993, Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene, J. Cell Biol., 121, 387, 10.1083/jcb.121.2.387
Pachter, 1984, The differential appearance of neurofilament triplet polypeptides in the developing rat optic nerve, Dev. Biol., 103, 200, 10.1016/0012-1606(84)90021-6
Pant, 1988, Dephosphorylation of neurofilament proteins enhances their susceptibility to degradation by calpain, Biochem. J., 256, 665, 10.1042/bj2560665
Parry, 1992, Intermediate filament structure, Curr. Opin. Cell Biol., 4, 94, 10.1016/0955-0674(92)90064-J
Roots, 1983, Neurofilament accumulation induced in synapses by leupeptin, Science, 221, 971, 10.1126/science.6192501
Rosen, 1993, Mutations in Cu/ Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis, Nature, 362, 59, 10.1038/362059a0
Sakaguchi, 1993, Reduced diameter and conductance velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail, Neurosci. Lett., 153, 65, 10.1016/0304-3940(93)90078-Y
Sambrook, 1989
Schmidt, 1987, Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls, Lab. Invest., 56, 282
Schmidt, 1989, Analysis of epitopes shared by Hirano bodies and human neurofilament proteins in normal and Alzheimer's disease hippocampus, Lab. Invest., 60, 513
Schmidt, 1991, Epitope map of neurofilament protein domains in cortical and peripheral nervous system Lewy bodies, Amer. J. Pathol., 139, 53
Shaw, 1982, Differential expression of neurofilament triplet proteins in brain development, Nature, 298, 277, 10.1038/298277a0
Steinert, 1988, Molecular and cellular biology of intermediate filaments, Annu. Rev. Biochem., 57, 593, 10.1146/annurev.bi.57.070188.003113
Sternberger, 1983, Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ, 80, 6126
Szaro, 1991, Inhibition of axonal development after injection of neurofilament antibodies into a Xenopus laevis embryo, J. Comp. Neurol., 308, 576, 10.1002/cne.903080406
Towbin, 1979, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications, 76, 4350
Toyoshima, 1989, Phosphorylation of neurofilament proteins and localization of axonal swellings in motor neuron disease, J. Neurol. Sci., 89, 269, 10.1016/0022-510X(89)90028-2
Troncoso, 1985, Aluminum intoxication: a disorder of neurofilament transport in motoneurons, Brain Res., 342, 172, 10.1016/0006-8993(85)91369-1
Troncoso, 1986, Immunocytochemical studies of neurofilament antigens in the neurofibrillary pathology induced by aluminum, Brain Res., 364, 295, 10.1016/0006-8993(86)90842-5
Tucker, 1989, In situ localization of microtubule-associated protein mRNA in the developing and adult rat brain, Neuron, 2, 1245, 10.1016/0896-6273(89)90309-7
Voyvodic, 1989, Target size regulates caliber and myelination of sympathetic axons, Nature, 342, 430, 10.1038/342430a0
Watson, 1989, Phosphorylation-dependent immunoreactivity of neurofilaments increases during axonal maturation and β,β-iminodiproprionitrile intoxication, J. Neurochem., 53, 1818, 10.1111/j.1471-4159.1989.tb09248.x
Willard, 1983, Modulation of neurofilament axonal transport during the development of rabbit retinal ganglion cells, Cell, 35, 551, 10.1016/0092-8674(83)90189-7
Wong, 1987, Changes in neurofilament gene expression occur after axotomy of dorsal root ganglion neurons: an in situ hybridization study, Metab. Brain Dis., 2, 291, 10.1007/BF00999699
Wu iek, 1986, The amount of slow axonal transport is proportional to the radial dimensions of the axon, J. Neurosci., 15, 75
Xu, 1993, Increased expression of neurofilament subunit NF-L produces morphological alterations that resemblethe pathologyof human motor neuron disease, Cell, 73, 23, 10.1016/0092-8674(93)90157-L
Yamasaki, 1991, Hereditary hypotrophic axonopathywith neurofilament deficiency in a mutant strain of the Japanese quail, Acta Neuropathol., 82, 427, 10.1007/BF00293376
Yamasaki, 1992, Defective expression of neurofilament protein subunits in hereditary hypotrophic axonopathy of quail, Lab. Invest., 66, 734
Zabin, 1982, β-Galactosidase a-complementation. A model for protein-protein interaction, Mol. Cell. Biochem., 49, 87