Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms
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Bai, 2001, Gli1 can rescue the in vivo function of Gli2, Development, 128, 5161, 10.1242/dev.128.24.5161
Chen, 1999, Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression, Cell, 98, 305, 10.1016/S0092-8674(00)81960-1
Cheng, 2002, Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18–mSin3 corepressor complex, Proc Natl Acad Sci USA, 99, 5442, 10.1073/pnas.082096999
Ding, 1999, Mouse Suppressor of fused is a negative regulator of Sonic Hedgehog signaling and alters the subcellular distribution of Gli1, Curr Biol, 9, 1119, 10.1016/S0960-9822(99)80482-5
Ding, 1998, Diminished Sonic Hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice, Development, 125, 2533, 10.1242/dev.125.14.2533
Dunaeva, 2003, Characterization of the physical interaction of Gli proteins with SUFU protein, J Biol Chem, 278, 5116, 10.1074/jbc.M209492200
Grimm, 2001, Genomic organization and embryonic expression of suppressor of fused, a candidate gene for the split-hand/split-foot malformation type 3, FEBS Lett, 505, 13, 10.1016/S0014-5793(01)02682-5
Henderson, 2000, A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals, Exp Cell Res, 256, 213, 10.1006/excr.2000.4825
Ingham, 2001, Hedgehog signaling in animal development: paradigms and principles, Genes Dev, 15, 3059, 10.1101/gad.938601
Kogerman, 1999, Mammalian Suppressor-of-fused modulates nuclear-cytoplasmic shuttling of GLI-1, Nat Cell Biol, 1, 312, 10.1038/13031
Kudo, 1998, Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1, Exp Cell Res, 242, 540, 10.1006/excr.1998.4136
Lum, 2004, The Hedgehog response network: sensors, switches, and routers, Science, 304, 1755, 10.1126/science.1098020
Mao, 2002, Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1, J Biol Chem, 277, 35156, 10.1074/jbc.M206743200
Meng, 2001, Suppressor of fused negatively regulates beta-catenin signaling, J Biol Chem, 276, 40113, 10.1074/jbc.M105317200
Merchant, 2004, Suppressor of fused regulates Gli activity through a dual binding mechanism, Mol Cell Biol, 24, 8627, 10.1128/MCB.24.19.8627-8641.2004
Methot, 2000, Suppressor of fused opposes Hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus, Development, 127, 4001, 10.1242/dev.127.18.4001
Murone, 2000, Gli regulation by the opposing activities of fused and suppressor of fused, Nat Cell Biol, 2, 310, 10.1038/35010610
Nieuwenhuis, 2005, Hedgehog signaling and congential malformations, Clin Genet, 67, 193, 10.1111/j.1399-0004.2004.00360.x
Ohlmeyer, 1998, Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator, Nature, 396, 749, 10.1038/25533
Paces-Fessy, 2004, The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, galectin3 and other nuclear proteins, Biochem J, 378, 353, 10.1042/bj20030786
Pearce, 1999, Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators, Dev Biol, 212, 323, 10.1006/dbio.1999.9335
Preat, 1992, Characterization of suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster, Genetics, 132, 725, 10.1093/genetics/132.3.725
Sasaki, 1997, A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro, Development, 124, 1313, 10.1242/dev.124.7.1313
Sheng, 2004, Activation of the Hedgehog pathway in advanced prostate cancer, Mol Cancer, 3, 29, 10.1186/1476-4598-3-29
Stegman, 2000, Identification of a tetrameric Hedgehog signaling complex, J Biol Chem, 275, 21809, 10.1074/jbc.C000043200
Stone, 1999, Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli, J Cell Sci, 112, 4437, 10.1242/jcs.112.23.4437
Taylor, 2004, Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling, Oncogene, 23, 4577, 10.1038/sj.onc.1207605
Wang, 2000, Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of Cubitus interruptus, Genes Dev, 14, 2893, 10.1101/gad.843900
Wang, 2004, Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms, Dev Biol, 268, 493, 10.1016/j.ydbio.2004.01.008
Wang, 1999, The subcellular localization and activity of Drosophila Cubitus interruptus are regulated at multiple levels, Development, 126, 5097, 10.1242/dev.126.22.5097
Wang, 2000, Nuclear import of Cubitus interruptus is regulated by hedgehog via a mechanism distinct from Ci stabilization and Ci activation, Development, 127, 3131, 10.1242/dev.127.14.3131
Wen, 1995, Identification of a signal for rapid export of proteins from the nucleus, Cell, 82, 463, 10.1016/0092-8674(95)90435-2