Natural Products as Sources of New Drugs over the Last 25 Years

Journal of Natural Products - Tập 70 Số 3 - Trang 461-477 - 2007
David Newman1, Gordon M. Cragg2
1Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute-Frederick, P.O. Box B, Frederick, MD 21702, USA.
2Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute-Frederick, P.O. Box B, Frederick, Maryland 21702

Tóm tắt

Từ khóa


Tài liệu tham khảo

Cragg G. M., 1997, J. Nat. Prod., 60, 60

Newman D. J., 2003, J. Nat. Prod., 66, 1037, 10.1021/np030096l

Pelish H. E., 2001, J. Am. Chem. Soc., 123, 6741, 10.1021/ja016093h

Spring D. R., 2003, Org. Biomol. Chem., 1, 3870, 10.1039/b310752n

Burke M. D., 2004, Angew. Chem., Int. Ed., 43, 58, 10.1002/anie.200300626

Zhonghong G., 2005, Angew. Chem., Int. Ed., 44, 1368

Reayi A., 2005, Curr. Opin. Chem. Biol., 9, 247, 10.1016/j.cbpa.2005.04.007

Lipinski C. A., 2004, Drug Discovery Today:  Technol

Macarron R., 2006, Drug Discovery Today, 11, 279, 10.1016/j.drudis.2006.02.001

Keller T. H., 2006, Curr. Opin. Chem. Biol., 10, 361, 10.1016/j.cbpa.2006.06.014

Allen R., 1984, Annual Reports in Medicinal Chemistry, 19, 326

Allen R., 1985, Annual Reports in Medicinal Chemistry, 20, 325

Allen R., 1986, Annual Reports in Medicinal Chemistry, 21, 335

Allen R., 1987, Annual Reports in Medicinal Chemistry, 22, 330

Ong, H. H.; Allen, R. C. InAnnual Reports in Medicinal Chemistry; Allen, R. C., Ed.; Academic Press:  San Diego, 1988; Vol. 23, pp 325- 348.

Ong, H. H.; Allen, R. C. InAnnual Reports in Medicinal Chemistry; Allen, R. C., Ed.; Academic Press:  San Diego, 1989; Vol. 24, pp 295−315.

Ong, H. H.; Allen, R. C. InAnnual Reports in Medicinal Chemistry; Bristol, J. A., Ed.; Academic Press:  San Diego, 1990; Vol. 25, pp 309−322.

Strupczewski, J. D.; Ellis, D. B.; Allen, R. C. InAnnual Reports inMedicinal Chemistry; Bristol, J. A., Ed.; Academic Press:  San Diego, 1991; Vol. 26, pp 297−313.

Strupczewski, J. D.; Ellis, D. B. InAnnual Reports in MedicinalChemistry; Bristol, J. A., Ed.; Academic Press:  San Diego, 1992; Vol. 27, pp 321−337.

Strupczewski, J. D.; Ellis, D. B. InAnnual Reports in MedicinalChemistry; Bristol, J. A., Ed.; Academic Press:  San Diego, 1993; Vol. 28, pp 325−341.

Cheng, X.M. InAnnual Reports in Medicinal Chemistry; Bristol, J. A., Ed.; Academic Press:  San Diego, 1994; Vol. 29, pp 331−354.

Cheng, X.M. InAnnual Reports in Medicinal Chemistry; Bristol, J. A., Ed.; Academic Press:  San Diego, 1995; Vol. 30, pp 295−317.

Cheng, X.M. InAnnual Reports in Medicinal Chemistry; Bristol, J. A., Ed.; Academic Press:  San Diego, 1996; Vol. 31, pp 337−355.

Galatsis, 1997, Annual Reports in Medicinal Chemistry, 32, 326

Galatsis, 1998, Annual Reports in Medicinal Chemistry, 33, 353

Gaudilliere, 1999, Annual Reports in Medicinal Chemistry, 34, 338

Gaudilliere, B.; Berna, P. InAnnual Reports in Medicinal Chemistry; Doherty, A. M., Ed.; Academic Press:  San Diego, 2000; Vol. 35, pp 331−355.

Gaudilliere, B.; Bernardelli, P.; Berna, P. InAnnual Reports in MedicinalChemistry; Doherty, A. M., Ed.; Academic Press:  San Diego, 2001; Vol. 36, pp 293−318.

Bernardelli, P.; Gaudilliere, B.; Vergne, F. InAnnual Reports inMedicinal Chemistry; Doherty, A. M., Ed.; Academic Press:  Amsterdam, 2002; Vol. 37, pp 257−277.

Boyer-Joubert, C.; Lorthiois, E.; Moreau, F. InAnnual Reports inMedicinal Chemistry; Doherty, A. M., Ed.; Academic Press:  Amsterdam, 2003; Vol. 38, pp 347−374.

Hegde, S.; Carter, J. InAnnual Reports in Medicinal Chemistry; Doherty, A. M., Ed.; Academic Press:  Amsterdam, 2004; Vol. 39, pp 337−368.

Hegde, S.; Schmidt, M. InAnnual Reports in Medicinal Chemistry; Doherty, A. M., Ed.; Academic Press:  Amsterdam, 2005; Vol. 40, pp 443−473.

Prous J. R., 1990, Drug News Perspect., 3, 29

Prous J. R., 1991, Drug News Perspect., 4, 109

Prous J. R., 1992, Drug News Perspect., 5, 101

Prous J. R., 1993, Drug News Perspect., 6, 106

Prous J. R., 1994, Drug News Perspect., 7, 36

Prous J. R., 1995, Drug News Perspect., 8, 37

Prous J. R., 1996, Drug News Perspect., 9, 32

Graul A. I., 1997, Drug News Perspect., 10, 18

Graul A. I., 1998, Drug News Perspect., 11, 32

Graul A. I., 1999, Drug News Perspect., 12, 43

Graul A. I., 2000, Drug News Perspect., 13, 53

Graul A. I., 2001, Drug News Perspect., 14, 31

Graul A. I., 2002, Drug News Perspect., 15, 43

Graul A. I., 2003, Drug News Perspect., 16, 39

Graul A. I., 2004, Drug News Perspect., 17, 57

Graul A. I., 2005, Drug News Perspect., 18, 36

Graul A. I., 2006, Drug News Perspect., 19, 53

Newman D. J., 2005, Modern Biopharmaceuticals, Design, Development and Optimization, 2, 496

Boyd M., 1993, Current Therapy in Oncology, 22

Sweetman S. C., 2002, The Complete Drug Reference, 33 ed

Hruby V., 2002, J. Nat. Rev., Drug Discovery, 1, 858

Wan Y., 2004, J. Med. Chem., 47, 6908

Georgsson J., 2006, Bioorg. Med. Chem., 14, 5972, 10.1016/j.bmc.2006.05.019

Steckelings U. M., 2005, Peptides, 26, 1409, 10.1016/j.peptides.2005.03.010

Newman D. J., 2000, Nat. Prod. Rep., 17, 234, 10.1039/a902202c

Breinbauer R., 2002, Curr. Med. Chem., 9, 2145, 10.2174/0929867023368773

Breinbauer R., 2002, Angew. Chem., Int. Ed., 41, 2890

Kingston D. G. I., 2002, J. Curr. Opin. Drug Discovery Dev., 5, 316

Newman D. J., 2002, Curr. Cancer Drug Targets, 2, 308, 10.2174/1568009023333791

Nielsen J., 2002, Curr. Opin. Chem. Biol., 6, 305, 10.1016/S1367-5931(02)00330-7

Perez J. J., 2002, Curr. Med. Chem., 9, 2229, 10.2174/0929867023368683

van Huijsduijnen R. H., 2002, Drug Discovery Today, 7, 1019, 10.1016/S1359-6446(02)02438-8

Barun O., 2004, Angew. Chem., Int. Ed., 43, 3199, 10.1002/anie.200353609

Balamurugan R., 2005, Mol. BioSyst., 1, 45, 10.1039/b503623b

Ganesan A., 2004, Curr. Opin. Biotech., 15, 590, 10.1016/j.copbio.2004.09.002

Shang S., 2005, Curr. Opin. Chem. Biol., 9, 258, 10.1016/j.cbpa.2005.03.006

Costantino L., 2006, Curr. Med. Chem., 13, 85, 10.2174/092986706775197999

Violette A., 2006, Chem. Biol., 13, 538, 10.1016/j.chembiol.2006.03.009

Baltz R. H., 2005, Nat. Prod. Rep., 22, 741, 10.1039/b416648p

Melby T., 2006, AIDS Res. Hum. Retroviruses, 22, 385, 10.1089/aid.2006.22.375

Yang S. S., 2001, J. Nat. Prod., 64, 277

Efferth T., 2005, Drug Res. Updates, 8, 97, 10.1016/j.drup.2005.04.003

Carter, S. K.; Bakowski, M. T.; Hellmann, K.Chemotherapy of Cancer; Wiley:  New York, 1977; p 350.

Cole, W. H.Chemotherapy of Cancer; Lea and Febiger:  Philadelphia, 1970; p 349.

Iltz J. L., 2006, Clin. Ther., 28, 665

Borman S., 2002, News

Wilson R. M., 2006, J. Acc. Chem. Res., 39, 539, 10.1021/ar068018n

Klotz U., 2006, Int. J. Clin. Pharmacol. Ther., 44, 483

Wermeling D. P., 2006, Pharmacotherapy, 26, 402, 10.1592/phco.26.3.395

Iyamu E. W., 2003, Br. J. Haematol., 122, 1008, 10.1046/j.1365-2141.2003.04536.x

Cordeiro N. J., 2004, Cochrane Database Syst. Rev

Bok J. W., 2006, Chem. Biol., 13, 37

Challis G. L., 2000, FEMS Microbiol. Lett., 187, 114, 10.1111/j.1574-6968.2000.tb09145.x

Lautru S., 2005, Nat. Chem. Biol., 1, 269, 10.1038/nchembio731

McAlpine J. B., 2005, J. Nat. Prod., 68, 496, 10.1021/np0401664

Piel J., 2004, Nat. Prod. Rep., 21, 538, 10.1039/b310175b

Piel J., 2005, BioSpektrum, 11, 173

Piel J., 2006, Curr. Med. Chem., 13, 50, 10.2174/092986706775197944

Piel J., 2005, J. Nat. Prod., 68, 479, 10.1021/np049612d

Piel J., 2004, Proc. Natl. Acad. Sci. U.S.A., 101, 16227, 10.1073/pnas.0405976101

Newman D. J., 2006, J. Ind. Microbiol. Biotechnol., 23, 544

Puri S. C., 2005, J. Nat. Prod., 68, 1719

Eyberger A. L., 2006, J. Nat. Prod., 69, 1124, 10.1021/np060174f

Yang X., 2004, Zhong Cao Yao, 35, 81

Gunatilaka A. A. L., 2006, J. Nat. Prod., 69, 526