Nail involvement can predict enthesopathy in patients with psoriasis

JDDG - Journal of the German Society of Dermatology - Tập 14 Số 11 - Trang 1102-1107 - 2016
María Castellanos‐González1, Beatriz Joven2, Julio Sánchez2, Eva Andrés3, F. Vanaclocha-Sebastián1, Pablo L. Ortiz‐Romero1, R. Rivera1
1Department of Dermatology and Venereology, Hospital Universitario, 12 de Octubre, Madrid, Spain
2Department of Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain
3Research Unit, Clinical, Epidemiology and Public Health CIBER, Hospital Universitario, 12 de Octubre, Madrid, Spain

Tóm tắt

SummaryBackground: Although subclinical enthesopathy is a well‐established diagnostic criterion for psoriatic arthritis (PsA), it is frequently overlooked, as many patients are asymptomatic. The possibility of finding a clinical clue predicting enthesopathy would help clinicians establish an early diagnosis of PsA.Material and methods: A prospective single‐center study of a total of 90 patients with psoriasis was conducted to assess the presence of entheseal abnormalities as detected by ultrasound, and to determine any correlation with nail involvement.Results: Entheseal abnormalities were found in 23 patients (25.5 %), 19 (82.6 %) of whom showed nail involvement, whereas four (17.4 %) individuals did not. Enthesopathy was present in 31.1 % (19/61) of patients with onychopathy compared to 13.8 % (4/29) of those without nail involvement (p  =  0.07). There was a significant correlation between target NAPSI score and evidence of enthesopathy. In addition, the number of nails affected also showed a significant correlation with the presence of enthesopathy (p  = 0.035).Conclusions: Clinical evidence of onychopathy may be the clue to an early diagnosis of enthesopathy in psoriasis patients.

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JDDG - Journal of the German Society of Dermatology

Tập 14 Số 11

1102-1107

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