NIHSS–the Alberta Stroke Program Early CT Score mismatch in guiding thrombolysis in patients with acute ischemic stroke

Amarenco P, Bogousslavsky J, Caplan LR, Donnan GA, Wolf ME, Hennerici MG (2013) The ASCOD phenotyping of ischemic stroke (Updated ASCO Phenotyping). Cerebrovasc Dis (Basel, Switz) 36:1–5. https://doi.org/10.1159/000352050

Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Das SR, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Jordan LC, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, O’Flaherty M, Pandey A, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Spartano NL, Stokes A, Tirschwell DL, Tsao CW, Turakhia MP, VanWagner LB, Wilkins JT, Wong SS, Virani SS (2019) Heart Disease and Stroke Statistics-2019 update: a report from the American Heart Association. Circulation 139:e56–e528. https://doi.org/10.1161/cir.0000000000000659

Xiong Y, Manwani B, Fisher M (2019) Management of acute ischemic stroke. Am J Med 132:286–291. https://doi.org/10.1016/j.amjmed.2018.10.019

Kate M, Wannamaker R, Kamble H, Riaz P, Gioia LC, Buck B, Jeerakathil T, Smyth P, Shuaib A, Emery D, Butcher K (2018) Penumbral imaging-based thrombolysis with tenecteplase is feasible up to 24 hours after symptom onset. J Stroke 20:122–130. https://doi.org/10.5853/jos.2017.00178

Tei H, Uchiyama S, Usui T (2007) Clinical-diffusion mismatch defined by NIHSS and ASPECTS in non-lacunar anterior circulation infarction. J Neurol 254:340–346. https://doi.org/10.1007/s00415-006-0368-8

Terasawa Y, Kimura K, Iguchi Y, Kobayashi K, Aoki J, Shibazaki K, Kaji R (2010) Could clinical diffusion-mismatch determined using DWI ASPECTS predict neurological improvement after thrombolysis before 3 h after acute stroke? J Neurol Neurosurg Psychiatry 81:864–868. https://doi.org/10.1136/jnnp.2009.190140

Nogueira RG, Kemmling A, Souza LM, Payabvash S, Hirsch JA, Yoo AJ, Lev MH (2017) Clinical diffusion mismatch better discriminates infarct growth than mean transit time-diffusion weighted imaging mismatch in patients with middle cerebral artery-M1 occlusion and limited infarct core. J Neurointerv Surg 9:127–130. https://doi.org/10.1136/neurintsurg-2014-011602

Raza SA, Barreira CM, Rodrigues GM, Frankel MR, Haussen DC, Nogueira RG, Rangaraju S (2019) Prognostic importance of CT ASPECTS and CT perfusion measures of infarction in anterior emergent large vessel occlusions. J Neurointerv Surg 11:670–674. https://doi.org/10.1136/neurintsurg-2018-014461

Sarraj A, Hassan AE, Grotta J, Sitton C, Cutter G, Cai C, Chen PR, Imam B, Pujara D, Arora A, Reddy S, Parsha K, Riascos RF, Vora N, Abraham M, Edgell R, Hellinger F, Haussen DC, Blackburn S, Kamal H, Barreto AD, Martin-Schild S, Lansberg M, Gupta R, Savitz S, Albers GW (2020) Optimizing patient Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT): a prospective multicenter cohort study of imaging selection. Ann Neurol. https://doi.org/10.1002/ana.25669

Kent DM, Hill MD, Ruthazer R, Coutts SB, Demchuk AM, Dzialowski I, Wunderlich O, von Kummer R (2005) “Clinical-CT mismatch” and the response to systemic thrombolytic therapy in acute ischemic stroke. Stroke 36:1695–1699. https://doi.org/10.1161/01.STR.0000173397.31469.4b

Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, Biller J, Brown M, Demaerschalk BM, Hoh B, Jauch EC, Kidwell CS, Leslie-Mazwi TM, Ovbiagele B, Scott PA, Sheth KN, Southerland AM, Summers DV, Tirschwell DL (2019) Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 50:e344–e418. https://doi.org/10.1161/str.0000000000000211

Ma H, Campbell BCV, Parsons MW, Churilov L, Levi CR, Hsu C, Kleinig TJ, Wijeratne T, Curtze S, Dewey HM, Miteff F, Tsai CH, Lee JT, Phan TG, Mahant N, Sun MC, Krause M, Sturm J, Grimley R, Chen CH, Hu CJ, Wong AA, Field D, Sun Y, Barber PA, Sabet A, Jannes J, Jeng JS, Clissold B, Markus R, Lin CH, Lien LM, Bladin CF, Christensen S, Yassi N, Sharma G, Bivard A, Desmond PM, Yan B, Mitchell PJ, Thijs V, Carey L, Meretoja A, Davis SM, Donnan GA (2019) Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke. N Engl J Med 380:1795–1803. https://doi.org/10.1056/NEJMoa1813046

Tang TY, Jiao Y, Cui Y, Zhao DL, Zhang Y, Wang Z, Meng XP, Yin XD, Yang YJ, Teng GJ, Ju SH (2020) Penumbra-based radiomics signature as prognostic biomarkers for thrombolysis of acute ischemic stroke patients: a multicenter cohort study. J Neurol. https://doi.org/10.1007/s00415-020-09713-7

Ma H, Wright P, Allport L, Phan TG, Churilov L, Ly J, Zavala JA, Arakawa S, Campbell B, Davis SM, Donnan GA (2015) Salvage of the PWI/DWI mismatch up to 48 h from stroke onset leads to favorable clinical outcome. Int J Stroke 10:565–570. https://doi.org/10.1111/ijs.12203

Berthezene Y, Eker O, Makris N, Bettan M, Mansuy A, Chabrol A, Mikkelsenm IK, Hermier M, Mechtouff L, Ong E, Derex L, Berner LP, Ameli R, Pedraza S, Thomalla G, Ostergaard L, Baron JC, Cho TH, Nighoghossian N (2018) Collateral circulation assessment within the 4.5 h time window in patients with and without DWI/FLAIR MRI mismatch. J Neurol Sci 394:94–98. https://doi.org/10.1016/j.jns.2018.09.013

Rava RA, Snyder KV, Mokin M, Waqas M, Allman AB, Senko JL, Podgorsak AR, Shiraz Bhurwani MM, Hoi Y, Siddiqui AH, Davies JM, Levy EI, Ionita CN (2020) Assessment of a Bayesian Vitrea CT perfusion analysis to predict final infarct and penumbra volumes in patients with acute ischemic stroke: a comparison with RAPID. Am J Neuroradiol. https://doi.org/10.3174/ajnr.A6395

Feil K, Reidler P, Kunz WG, Kupper C, Heinrich J, Laub C, Muller K, Voglein J, Liebig T, Dieterich M, Kellert L (2020) Addressing a real-life problem: treatment with intravenous thrombolysis and mechanical thrombectomy in acute stroke patients with an extended time window beyond 4.5 h based on computed tomography perfusion imaging. Eur J Neurol 27:168–174. https://doi.org/10.1111/ene.14051

Yoo AJ, Berkhemer OA, Fransen PSS, van den Berg LA, Beumer D, Lingsma HF, Schonewille WJ, Sprengers MES, van den Berg R, van Walderveen MAA, Beenen LFM, Wermer MJH, Nijeholt G, Boiten J, Jenniskens SFM, Bot JCJ, Boers AMM, Marquering HA, Roos Y, van Oostenbrugge RJ, Dippel DWJ, van der Lugt A, van Zwam WH, Majoie C (2016) Effect of baseline Alberta Stroke Program Early CT Score on safety and efficacy of intra-arterial treatment: a subgroup analysis of a randomised phase 3 trial (MR CLEAN). Lancet Neurol 15:685–694. https://doi.org/10.1016/s1474-4422(16)00124-1

Goyal M, Menon BK, Coutts SB, Hill MD, Demchuk AM (2011) Effect of baseline CT scan appearance and time to recanalization on clinical outcomes in endovascular thrombectomy of acute ischemic strokes. Stroke 42:93–97. https://doi.org/10.1161/strokeaha.110.594481

Bandettini di Poggio M, Finocchi C, Brizzo F, Altomonte F, Bovis F, Mavilio N, Serrati C, Malfatto L, Mancardi G, Balestrino M (2019) Management of acute ischemic stroke, thrombolysis rate, and predictors of clinical outcome, Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of. Clin Neurophysiol 40:319–326. https://doi.org/10.1007/s10072-018-3644-3