Mutations in the Genes for Oocyte-Derived Growth Factors GDF9 and BMP15 Are Associated with Both Increased Ovulation Rate and Sterility in Cambridge and Belclare Sheep (Ovis aries)1
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1996, Reproductive physiology and endocrinology of prolific sheep., Prolific Sheep, 453
1982, Segregation of a major gene influencing fecundity in progeny of Booroola sheep., NZ J Agric Res, 25, 525, 10.1080/00288233.1982.10425216
1982, Genetic segregation for fecundity in Booroola Merino sheep., Proceedings of the World Congress on Sheep and Beef Cattle Breeding, 395
1991, Evidence for the presence of a major gene influencing ovulation rate on the X-chromosome of sheep., Biol Reprod, 44, 620, 10.1095/biolreprod44.4.620
1985, Variation and repeatability of ovulation rate in Cambridge ewes., Anim Prod, 40, 529
1985, Single genes for fecundity in Icelandic sheep., Genetics of Reproduction in Sheep, 159, 10.1016/B978-0-407-00302-6.50020-9
1986, Reproduction in Javanese sheep: evidence for a gene with large effect on ovulation rate and litter size., J Anim Sci, 63, 418, 10.2527/jas1986.632418x
1988, Inheritance of high prolificacy of the Olkuska sheep (preliminary results)., J Agric Sci Finland, 60, 597
1991, Evidence for single gene effects on ovulation rate in the Cambridge and Belclare breeds., Major Genes for Reproduction in Sheep, 93
1998; , ,, Hyper-prolificacy in the French Lacaune sheep breed; a possible major gene., Proceedings of the 6th World Congress on Genetics Applied to Livestock Production;, 27, 11
2001, Evidence that an imprinted gene on the X chromosome increases ovulation rate in sheep., Biol Reprod, 64, 216, 10.1095/biolreprod64.1.216
1992, Infertility due to bilateral ovarian hypoplasia in sheep homozygous (FecXI FecXI) for the Inverdale prolificacy gene located on the X chromosome., Biol Reprod, 46, 636, 10.1095/biolreprod46.4.636
1993, Ovaries of ewes homozygous for the X-linked Inverdale gene (FecXI) are devoid of secondary and tertiary follicles but contain many abnormal structures., Biol Reprod, 49, 895, 10.1095/biolreprod49.5.895
1993, The ovine Booroola fecundity gene (FecB) is linked to markers from a region of human chromosome 4q., Nat Genet, 4, 410, 10.1038/ng0893-410
1985, The single gene inheritance of the high litter size of the Booroola merino., Genetics of Reproduction in Sheep, 115, 10.1016/B978-0-407-00302-6.50016-7
2001, Mutation in bone morphogenetic protein receptor-1B is associated with increased ovulation rate in Booroola Merino ewes., Proc Natl Acad Sci U S A, 98, 5104, 10.1073/pnas.091577598
2001, Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells., Biol Reprod, 64, 1225, 10.1095/biolreprod64.4.1225
2001, The Booroola (FecB) phenotype is associated with a mutation in the bone morphogenetic receptor type 1B (BMPR1B) gene., J Endocrinol, 169, R1, 10.1677/joe.0.169R001
2002, Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner., Nat Genet, 25, 279
2001, Ovulation rate and litter size of prolific Inverdale (FecXI) and Hanna (FecXH) sheep., Proc Assoc Advancement Anim Breeding Genet, 14, 175
2002, DNA tests in prolific sheep from eight countries provide new evidence on origin of the Booroola (FecB) mutation., Biol Reprod, 66, 1869, 10.1095/biolreprod66.6.1869
1996, Major gene effects on reproduction in sheep., Irish J Agric Food Res, 35, 87
1997, Ovarian hypoplasia in Cambridge and Belclare ewes., Belclare Research Centre Research Report, 24
2001, Autosomal gene affecting the structure and function of the sheep ovary., Irish Grassland and Animal Production Association Proceedings of Agricultural Research Forum, 50
1995, Oocyte-specific expression of growth differentiation factor-9., Mol Endocrinol, 9, 131
1998, A novel growth differentiation factor-9 (GDF-9) related factor is co-expressed with GDF-9 in mouse oocytes during folliculogenesis., Mech Dev, 78, 135, 10.1016/S0925-4773(98)00161-0
1996, Growth differentiation factor-9 is required during early ovarian folliculogenesis., Nature, 383, 531, 10.1038/383531a0
1998, The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes., Mol Endocrinol, 12, 1809, 10.1210/mend.12.12.0206
2001, Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function., Mol Endocrinol, 15, 854, 10.1210/mend.15.6.0662
2002, Genetic mapping of ovine growth differentiation factor 9 (GDF9) to sheep chromosome 5., Anim Genet, 33, 244, 10.1046/j.1365-2052.2002.t01-11-00876.x
1999, Molecular cloning of the ovine growth/differentiation factor-9 gene and expression of growth/differentiation factor-9 in ovine and bovine ovaries., Biol Reprod, 60, 381, 10.1095/biolreprod60.2.381
1963, The genetic improvement of hill and lowland ewes—High Fertility ewes., Animal Production Division Research Report, 78
1976, Sheep Production, 366
1990, Extraction of DNA from sheep white blood cells., NZ J Agric Res, 33, 437, 10.1080/00288233.1990.10428440
2001, An enhanced linkage map of the sheep genome comprising more than 1000 loci., Genome Res, 11, 1275, 10.1101/gr.GR-1350R
1996, Mendelian Inheritance in Sheep (MIS 96), 75
1999, Human growth differentiation factor-9 (GDF-9) and its novel homolog GDF-9B are expressed during early folliculogenesis., J Clin Endocrinol Metab, 84, 2744
1999, Localisation of growth differentiation factor-9 (Gdf-9) mRNA and protein in rat ovaries and cDNA cloning of rat GDF-9 and its novel homolog GDF-9B., Mol Cell Endocrinol, 156, 189, 10.1016/S0303-7207(99)00100-8
2000, Expression of growth and differentiation factor-9 in the ovaries of fetal sheep homozygous or heterozygous for the Inverdale prolificacy gene (FecXI)., Biol Reprod, 62, 1479, 10.1095/biolreprod62.6.1479
2002, Expression of mRNA encoding growth differentiation factor 9 and bone morphogenetic protein 15 during follicular formation and growth in a marsupial, the brushtail possum (Trichasurus vulpecula)., Mol Cell Endocrinol, 192, 115, 10.1016/S0303-7207(02)00085-0
2002, Growth differentiation factor 9 and bone morphogenetic protein 15 are essential for ovarian follicular development in sheep., Biol Reprod, 67, 1777, 10.1095/biolreprod.102.007146
2003, The role of bone morphogenetic proteins in ovarian function., Reproduction, 61, 323
2002, Aberrant expression of growth differentiation factor-9 in oocytes of women with polycystic ovary syndrome., J Clin Endocrinol Metab, 87, 1337, 10.1210/jcem.87.3.8316
2002, Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9., Biol Reprod, 67, 473, 10.1095/biolreprod67.2.473
2003, Molecular basis of bone morphogenic protein-15 signalling in granulosa cells., J Biol Chem, 278, 304, 10.1074/jbc.M207362200
2000, BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II., EMBO J, 19, 3314, 10.1093/emboj/19.13.3314
2003, The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly., Mol Cell, 11, 605, 10.1016/S1097-2765(03)00094-7
2003, Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-β ligand:receptor interactions., EMBO J, 22, 1555, 10.1093/emboj/cdg156
2000, Crystal structure of the BMP2-BRIA ectodomain complex., Nature Structural Biol, 7, 492, 10.1038/75903
1996, Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily., Proc Natl Acad Sci U S A, 93, 878, 10.1073/pnas.93.2.878