Mutations in Plasmodium falciparum K13 propeller gene from Bangladesh (2009–2013)

Abu Naser Mohon1, Mohammad Shafiul Alam2, Abebe Genetu Bayih1, Asongna Folefoc3, Dea Shahinas4, Rashidul Haque2, Dylan R. Pillai3
1Department of Microbiology, Immunology and Infectious Diseases, Faculty of Medicine, University of Calgary, Diagnostic and Scientific Centre, Room 1 W-416, 9-3535 Research Road NW, Calgary, AB T2L 2 K8, Canada
2Parasitology Research Group, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
3Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Calgary, Calgary, Canada
4Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

Tóm tắt

Từ khóa


Tài liệu tham khảo

Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, Lwin KM, Ariey F, Hanpithakpong W, Lee SJ: Artemisinin resistance in Plasmodium falciparum malaria. New Engl J Med. 2009, 361: 455-467. 10.1056/NEJMoa0808859.

Witkowski B, Amaratunga C, Khim N, Sreng S, Chim P, Kim S, Lim P, Mao S, Sopha C, Sam B: Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies. Lancet Infect Dis. 2013, 13: 1043-1049. 10.1016/S1473-3099(13)70252-4.

O’Brien C, Henrich PP, Passi N, Fidock DA: Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum. Curr Opin Infect Dis. 2011, 24: 570-10.1097/QCO.0b013e32834cd3ed.

Dhanoa BS, Cogliati T, Satish AG, Bruford EA, Friedman JS: Update on the Kelch-like (KLHL) gene family. Hum Genomics. 2013, 7: 13-10.1186/1479-7364-7-13.

Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, Kim S, Duru V, Bouchier C, Ma L, Lim P, Leang R, Duong S, Sreng S, Suon S, Chuor CM, Bout DM, Menard S, Rogers WO, Genton B, Fandeur T, Miotto O, Ringwald P, Le Bras J, Berry A, Barale JC, Fairhurst RM, Benoit-Vical F, Mercereau-Puijalon O, Menard D: A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature. 2014, 505: 50-55.

Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M: Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Gene Dev. 1999, 13: 76-86. 10.1101/gad.13.1.76.

Zhang DD, Hannink M: Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol. 2003, 23: 8137-8151. 10.1128/MCB.23.22.8137-8151.2003.

Haque U, Overgaard HJ, Clements ACA, Norris DE, Islam N, Karim J, Roy S, Haque W, Kabir M, Smith DL: Malaria burden and control in Bangladesh and prospects for elimination: an epidemiological and economic assessment. Lancet Glob Health. 2014, 2: e98-e105. 10.1016/S2214-109X(13)70176-1.

JICPD: Joint International Continued Professional Development Meeting. Bangladesh College of Physicians and Surgeons: 22–23 February, 2004. 2004, Dhaka: BCPS

Haque R, Thriemer K, Wang Z, Sato K, Wagatsuma Y, Salam MA, Akther S, Akter J, Fukuda M, Miller RS: Therapeutic efficacy of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Bangladesh. Am J Trop Med Hyg. 2007, 76: 39-41.

Starzengruber P, Swoboda P, Fuehrer H-P, Khan WA, Hofecker V, Siedl A, Fally M, Graf O, Teja-Isavadharm P, Haque R: Current status of artemisinin-resistant falciparum malaria in South Asia: a randomized controlled artesunate monotherapy trial in Bangladesh. PLoS One. 2012, 7: e52236-10.1371/journal.pone.0052236.

Takala-Harrison S, Clark TG, Jacob CG, Cummings MP, Miotto O, Dondorp AM, Fukuda MM, Nosten F, Noedl H, Imwong M: Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia. Proc Natl Acad Sci U S A. 2012, 110: 240-245.

Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, McGready R, Al-Saai S, Dondorp AM, Lwin KM, Singhasivanon P: Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. Lancet. 2012, 379: 1960-1966. 10.1016/S0140-6736(12)60484-X.

Phompradit P, Muhamad P, Wisedpanichkij R, Chaijaroenkul W, Na-Bangchang K: Four years’ monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border. Malar J. 2014, 13: 23-10.1186/1475-2875-13-23.

Kyaw MP, Nyunt MH, Chit K, Aye MM, Aye KH, Lindegardh N, Tarning J, Imwong M, Jacob CG, Rasmussen C: Reduced susceptibility of Plasmodium falciparum to artesunate in southern Myanmar. PLoS One. 2013, 8: e57689-10.1371/journal.pone.0057689.

Roper C, Pearce R, Nair S, Sharp B, Nosten F, Anderson T: Intercontinental spread of pyrimethamine-resistant malaria. Science. 2004, 305 (5687): 1124-10.1126/science.1098876.

Verdrager J: Epidemiology of the emergence and spread of drug-resistant falciparum malaria in South-East Asia and Australasia. J Trop Med Hyg. 1986, 89 (6): 277-289.

Alam MS, Mohon AN, Mustafa S, Khan WA, Islam N, Karim MJ, Khanum H, Sullivan DJ, Haque R: Real-time PCR assay and rapid diagnostic tests for the diagnosis of clinically suspected malaria patients in Bangladesh. Malar J. 2011, 10: 175-10.1186/1475-2875-10-175.

Snounou G, Viriyakosol S, Zhu XP, Jarra W, Pinheiro L, Do Rosario VE, Thaithong S, Brown KN: High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasit. 1993, 61: 315-320. 10.1016/0166-6851(93)90077-B.

Thompson JD, Higgins DG, Gibson TJ, Clustal W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994, 22: 4673-4680. 10.1093/nar/22.22.4673.

Clamp M, Cuff J, Searle SM, Barton GJ: The jalview java alignment editor. Bioinformatics. 2004, 20: 426-427. 10.1093/bioinformatics/btg430.

Kelley LA, Sternberg MJE: Protein structure prediction on the Web: a case study using the Phyre server. Nat Prot. 2009, 4: 363-371. 10.1038/nprot.2009.2.

Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G: Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature. 2012, 482: 98-102. 10.1038/nature10814.

Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang M-I, Kobayashi A, Yokoyama S, Yamamoto M: Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. Mol Cell. 2006, 21: 689-700. 10.1016/j.molcel.2006.01.013.

Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Mao S, Sam B: Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014, 371: 411-423. 10.1056/NEJMoa1314981.

White NJ: Antimalarial drug resistance. J Clin Invest. 2004, 113: 1084-1092. 10.1172/JCI21682.

Alam MS, Chakma S, Khan WA, Glass GE, Mohon AN, Elahi R, Norris LC, Podder MP, Ahmed S, Haque R, Sack DA, Sullivan DJ, Norris DE: Diversity of anopheline species and their Plasmodium infection status in rural Bandarban, Bangladesh. Parasit Vectors. 2012, 5: 150-10.1186/1756-3305-5-150.

Alam MS, Khan MG, Chaudhury N, Deloer S, Nazib F, Bangali AM, Haque R: Prevalence of anopheline species and their Plasmodium infection status in epidemic-prone border areas of Bangladesh. Malar J. 2010, 9: 15-10.1186/1475-2875-9-15.

Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, Fukuda MM, Hien TT, Mayxay M, Noedl H: Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. J Infect Dis. 2014, jiu491-Epub ahead of print

World Health Organization: Global Plan for Artemisinin Resistance Containment (GPARC). 2011, Geneva: WHO

Maude RJ, Pontavornpinyo W, Saralamba S, Aguas R, Yeung S, Dondorp AM, Day NPJ, White NJ, White LJ: The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia. Malar J. 2009, 8: 31-10.1186/1475-2875-8-31.