Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

Immunopharmacology - Tập 39 Số 3 - Trang 167-180 - 1998
Małgorzata Kohutnicka1, Eliza Lewandowska2, Iwona Kurkowska‐Jastrzębska3, Andrzej Członkowski3, Anna Członkowska2
1Department of Experimental and Clinical Pharmacology, Medical Academy of Warsaw, Poland.
2Institute of Psychiatry and Neurology, Al. Sobieskiego 1/9, 02-957 Warsaw, Poland
3Department of Experimental and Clinical Pharmacology, Medical Academy of Warsaw, Warsaw, Poland

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Adams, 1989, The acute histopathology of MPTP in the mouse CNS, Brain Res. Bull., 23, 1, 10.1016/0361-9230(89)90157-3

Aderka, 1989, IL-6 inhibits lipopolisacharide-induced tumor necrosis factor production in cultured human monocytes and U937 cells in mice, J. Immunol., 143, 3517, 10.4049/jimmunol.143.11.3517

Banati, 1993, Cytotoxicity of microglia, Glia, 7, 111, 10.1002/glia.440070117

Banati, 1994, Modulation of intracellular formation of reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by propentophylline, J. Cereb. Blood Flow Metab., 14, 145, 10.1038/jcbfm.1994.19

Chao, 1992, Cytokine release from microglia: different inhibition by pentoxifylline and dexamethasone, J. Infect. Dis., 166, 847, 10.1093/infdis/166.4.847

Członkowska, 1996, Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model, Neurodegeneration, 5, 137, 10.1006/neur.1996.0020

Date, 1990, Long-term effect of MPTP in the mouse brain in relation to ageing: neurochemical and immunocytochemical analysis, Brain Res., 519, 266, 10.1016/0006-8993(90)90088-S

Eddelston, 1993, Molecular profile of reactive astrocytes—implications for their role in neurologic disease, Neuroscience, 54, 15, 10.1016/0306-4522(93)90380-X

Fattori, 1995, IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage, Eur. J. Neurosci., 7, 2441, 10.1111/j.1460-9568.1995.tb01042.x

Francis, 1995, Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum, Neurotoxicol. Neuroteratol., 17, 7, 10.1016/0892-0362(94)00048-I

Frei, 1987, Antigen presentation and tumor cytotoxicity by interferon-γ-treated microglial cells, Eur. J. Immunol., 17, 1271, 10.1002/eji.1830170909

Frei, 1989, On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases, Eur. J. Neurosci., 19, 686

Gehrmann, J., Kreutzberg, G.W., 1995. Microglia in experimental neuropathology. In: Kettenmann, H., Randsom, B. (Eds.), Neuroglilal Cells. Oxford University Press, pp. 883–904.

Gehrmann, 1991, Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus, Acta Neuropathol., 82, 442, 10.1007/BF00293378

Gehrmann, 1993, Microglial involvement in experimental autoimmune inflammation of the central and peripheral nervous system, Glia, 7, 50, 10.1002/glia.440070110

Giulian, 1993, Reactive glia as rivals in regulating neuronal survival, Glia, 7, 102, 10.1002/glia.440070116

Giulian, 1988, Colony stimulating factors as promotors of ameboid microglia, J. Neurosci., 85, 317

Giulian, 1985, Interleukin-1 stimulation of astroglial proliferation after brain injury, Science, 228, 497, 10.1126/science.3872478

Giulian, 1993, Brain glia release factors with opposing actions upon neuronal survival, J. Neurosci., 13, 29, 10.1523/JNEUROSCI.13-01-00029.1993

Giulian, 1994, Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture, Neurochem. Int., 25, 227, 10.1016/0197-0186(94)90066-3

Graeber, 1990, Microglia: immune network in the CNS, Brain Pathol., 1, 2, 10.1111/j.1750-3639.1990.tb00630.x

Hama, 1991, Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholonergic neurons from postnatal, two-week-old rats in cultures, Neuroscience, 40, 445, 10.1016/0306-4522(91)90132-8

Heikkila, 1987, The use of the MPTP-treated mouse as an animal model of parkinsonism, Can. J. Neurol. Sci., 14, 436, 10.1017/S0317167100037860

Kettenmann, 1993, Electrophysiological behavior of microglia, Glia, 7, 93, 10.1002/glia.440070115

Kiefer, 1991, Effects of dexamethasone on microglial activation in vivo: Selective downregulation of major histocompatibility complex class II expression in regenerating facial nucleus, J. Neuroimmunol., 34, 99, 10.1016/0165-5728(91)90119-R

Kitt, 1987, Injury of catecholaminergic neurons after acute exposure to MPTP. A TH immunocytochemical study in the monkey, Ann. New York Acad. Sci., 495, 730, 10.1111/j.1749-6632.1987.tb23724.x

Klein, 1997, Impaired neuroglial activation in interleukin-6 deficient mouse, Glia, 19, 227, 10.1002/(SICI)1098-1136(199703)19:3<227::AID-GLIA5>3.0.CO;2-W

Kopin, 1992, Features of the dopaminergic neurotoxin MPTP, Ann. New York Acad. Sci., 648, 96, 10.1111/j.1749-6632.1992.tb24527.x

Kushima, 1992, Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains, Neurosci. Res., 13, 267, 10.1016/0168-0102(92)90039-F

Langeveld, 1995, Cultured rat striatal and cortical astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development, Neurosci. Lett., 192, 13, 10.1016/0304-3940(95)11596-O

Langston, 1984, Pargyline prevents MPTP-induced Parkinsonism in primates, Science, 225, 1480, 10.1126/science.6332378

McGeer, 1988, Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains, Neurology, 38, 1285, 10.1212/WNL.38.8.1285

McGeer, 1991, Reactions of the immune system in chronic degenerative neurological diseases, Can. J. Neurol. Sci., 18, 376, 10.1017/S0317167100032479

Michael, 1994, Astrocyte responses to CNS injury, J. Neuropathol. Exp. Neurol., 53, 213, 10.1097/00005072-199405000-00001

Müller, 1995, Astroglial neurotrophic and neurite-promoting factors, Pharmacol. Ther., 65, 1, 10.1016/0163-7258(94)00047-7

Nohava, 1992, Neurons and neuroblastoma as a source of macrophage colony-stimulating factor, Eur. J. Immunol., 22, 2539, 10.1002/eji.1830221012

O'Callaghan, 1990, Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Brain Res., 521, 73, 10.1016/0006-8993(90)91526-M

Raivich, 1994, Inhibition of posttraumatic microglial proliferation in a genetic model of macrophage colony-stimulating factor deficiency in mouse, Eur. J. Neurosci., 6, 1616, 10.1111/j.1460-9568.1994.tb00552.x

Reinhard, 1988, The neurotoxicant MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) increases glial fibryllary acidic protein and decreases dopamine levels of the mouse striatum: evidence for glial response to injury, Neurosci. Lett., 95, 246, 10.1016/0304-3940(88)90665-9

Ricaurete, 1987, Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced degeneration of dopaminergic neurons in the substantia nigra, Brain Res., 403, 45

Schöbitz, 1993, Cellular localization of interleukin-6 mRNA and interleukin-6 receptor mRNA in rat brain, Eur. J. Neurosci., 5, 1426, 10.1111/j.1460-9568.1993.tb00210.x

Shrikant, 1996, The central nervous system as an immunocompetent organ, J. Immunol., 157, 1819, 10.4049/jimmunol.157.5.1819

Sonsalla, 1986, The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice, Eur. J. Pharmacol., 129, 339, 10.1016/0014-2999(86)90444-9

Sundström, E., Henriksson, B.G., Mohammed, A.H., Souverbie, F., 1994. MPTP-treated mice: a useful model for Parkinson's disease? In: Woodruff, M.L., Nonneman, A.J. (Eds.), Toxin-induced models of neurological disorders. Plenum, New York, pp. 121–137.