Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase

Warnakulasuriya, 2009, Global epidemiology of oral and oropharyngeal cancer, Oral Oncol, 45, 309, 10.1016/j.oraloncology.2008.06.002 2012 Forastiere, 2001, Head and neck cancer, N Engl J Med, 345, 1890, 10.1056/NEJMra001375 Vedtofte, 1987, Surgical treatment of premalignant lesions of the oral mucosa, Int J Oral Maxillofac Surg, 16, 656, 10.1016/S0901-5027(87)80049-8 Cheng, 2011, Expression of vascular endothelial growth factor is significantly associated with progression and prognosis of oral squamous cell carcinomas in Taiwan, J Formos Med Assoc, 110, 50, 10.1016/S0929-6646(11)60008-9 Shieh, 2011, Lysyl oxidase-like 3 mRNA expression indicates poor survival from oral squamous cell carcinoma, J Dent Sci, 6, 205, 10.1016/j.jds.2011.09.004 Dolmans, 2003, Photodynamic therapy for cancer, Nat Rev Cancer, 3, 380, 10.1038/nrc1071 Chang, 2010, Enhancement of 5-aminolevulinic acid-induced photodynamic therapy by a bioadhesive polymer, J Dent Sci, 5, 30, 10.1016/S1991-7902(10)60005-0 Grant, 1993, Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid, Lancet, 342, 147, 10.1016/0140-6736(93)91347-O Fan, 1996, Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity, Cancer, 78, 1374, 10.1002/(SICI)1097-0142(19961001)78:7<1374::AID-CNCR2>3.0.CO;2-L Chen, 2005, Successful treatment of an extensive verrucous carcinoma with topical 5-aminolevulinic acid-mediated photodynamic therapy, J Oral Pathol Med, 34, 253, 10.1111/j.1600-0714.2004.00267.x Chen, 2010, Successful treatment of an early invasive oral squamous cell carcinoma with topical 5-aminolevulinic acid-mediated photodynamic therapy, J Dent Sci, 5, 36, 10.1016/S1991-7902(10)60006-2 Kübler, 1998, Treatment of oral leukoplakia by topical application of 5-aminolevulinic acid, Int J Oral Maxillofac Surg, 27, 466, 10.1016/S0901-5027(98)80040-4 Sieroń, 2003, Photodynamic therapy (PDT) using topically applied delta-aminolevulinic acid (ALA) for the treatment of oral leukoplakia, J Oral Pathol Med, 32, 330, 10.1034/j.1600-0714.2003.00068.x Shafirstein, 2011, Using 5-aminolevulinic acid and pulsed dye laser for photodynamic treatment of oral leukoplakia, Arch Otolaryngol Head Neck Surg, 137, 1117, 10.1001/archoto.2011.178 Kawczyk-Krupka, 2012, Comparison of cryotherapy and photodynamic therapy in treatment of oral leukoplakia, Photodiagnosis Photodyn Ther, 9, 148, 10.1016/j.pdpdt.2011.12.007 Chen, 2005, Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy, Lasers Surg Med, 37, 114, 10.1002/lsm.20214 Chen, 2007, Topical 5-aminolevulinic acid-mediated photodynamic therapy for oral verrucous hyperplasia, oral leukoplakia and oral erythroleukoplakia, Photodiagnosis Photodyn Ther, 4, 44, 10.1016/j.pdpdt.2006.11.003 Chen, 2004, Successful treatment of oral verrucous hyperplasia with topical 5-aminolevulinic acid-mediated photodynamic therapy, Oral Oncol, 40, 630, 10.1016/j.oraloncology.2003.12.010 Yu, 2008, Photodynamic therapy outcome for oral verrucous hyperplasia depends on the clinical appearance, size, color, epithelial dysplasia, and surface keratin thickness of the lesion, Oral Oncol, 44, 595, 10.1016/j.oraloncology.2007.08.016 Lin, 2010, Topical photodynamic therapy is very effective for oral verrucous hyperplasia and oral erythroleukoplakia, J Oral Pathol Med, 39, 624, 10.1111/j.1600-0714.2010.00935.x Yu, 2009, Comparison of clinical outcomes of oral erythroleukoplakia treated with photodynamic therapy using either light-emitting diode or laser light, Lasers Surg Med, 41, 628, 10.1002/lsm.20841 Ortel, 2002, Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells, Br J Cancer, 87, 1321, 10.1038/sj.bjc.6600575 Ortel, 1998, Differentiation-specific increase in ALA-induced protoporphyrin IX accumulation in primary mouse keratinocytes, Br J Cancer, 77, 1744, 10.1038/bjc.1998.292 Sinha, 2006, Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells, Br J Cancer, 95, 485, 10.1038/sj.bjc.6603273 Anand, 2009, Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo, Clin Cancer Res, 15, 3333, 10.1158/1078-0432.CCR-08-3054 Anand, 2009, Enhancement of tumor responsiveness to aminolevulinate-photodynamic therapy (ALA-PDT) using differentiation-promoting agents in mouse models of skin carcinoma, Proc SPIE, 7380, 73804B, 10.1117/12.822972 Maytin, 2009, Enhancement and optimization of PpIX-based photodynamic therapy of skin cancer: translational studies from bench to clinic, Proc SPIE, 7164, 71640k, 10.1117/12.808174 Kondo, 1993, Heme-biosynthetic enzyme activities and porphyrin accumulation in normal liver and hepatoma cell lines of rat, Cell Biol Toxicol, 9, 95, 10.1007/BF00755143 Ohgari, 2005, Mechanisms involved in delta-aminolevulinic acid (ALA)-induced photosensitivity of tumor cells: relation of ferrochelatase and uptake of ALA to the accumulation of protoporphyrin, Biochem Pharmacol, 71, 42, 10.1016/j.bcp.2005.10.019 Sato, 2007, Vitamin D enhances ALA-induced protoporphyrin IX production and photodynamic cell death in 3-D organotypic cultures of keratinocytes, J Invest Dermatol, 127, 925, 10.1038/sj.jid.5700595 Anand, 2011, Vitamin D3 enhances the apoptotic response of epithelial tumors to aminolevulinate-based photodynamic therapy, Cancer Res, 71, 6040, 10.1158/0008-5472.CAN-11-0805 Chen, 2012, 5-Aminolevulinic acid-mediated photodynamic therapy for oral cancers and precancers, J Dent Sci, 7, 307, 10.1016/j.jds.2012.03.023 Mi, 2011, A randomized clinical comparative study of cryotherapy plus photodynamic therapy vs. cryotherapy in the treatment of multiple condylomata acuminata, Photodermatol Photoimmunol Photomed, 27, 176, 10.1111/j.1600-0781.2011.00592.x Chang, 2013, Successful treatment of a large oral verrucous hyperplasia with photodynamic therapy combined with cryotherapy, J Dent Sci, 8, 87, 10.1016/j.jds.2012.09.024 Lin, 2011, Modulation of serum anti-thyroglobulin and anti-thyroid microsomal autoantibody levels by levamisole in patients with oral lichen planus, J Formos Med Assoc, 110, 169, 10.1016/S0929-6646(11)60027-2 Lin, 2011, Modulation of serum antinuclear antibody levels by levamisole treatment in patients with oral lichen planus, J Formos Med Assoc, 110, 316, 10.1016/S0929-6646(11)60047-8 Kuo, 2013, Prompt healing of erosive oral lichen planus lesion after combined corticosteroid treatment with locally injected triamcinolone acetonide plus oral prednisolone, J Formos Med Assoc, 112, 216, 10.1016/j.jfma.2012.01.014