Metformin-associated lactic acidosis: Current perspectives on causes and risk
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Inzucchi, 2012, Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD), Diabetes Care, 35, 1364, 10.2337/dc12-0413
Davidson, 1997, An overview of metformin in the treatment of type 2 diabetes mellitus, Am J Med, 102, 99, 10.1016/S0002-9343(96)00353-1
2012, Standards of medical care in diabetes—2012, Diabetes Care, 35, S11
Huang, 2015, Helicobacter pylori infection decreases metformin tolerance in patients with type 2 diabetes mellitus, Diabetes Technol Ther, 17, 128, 10.1089/dia.2014.0203
2009
Peters, 2008, Metformin-associated lactic acidosis in an intensive care unit, Crit Care, 12, R149, 10.1186/cc7137
Misbin, 1998, Lactic acidosis in patients with diabetes treated with metformin, N Engl J Med, 338, 265, 10.1056/NEJM199801223380415
Rocha, 2013, Metformin in patients with chronic kidney disease: strengths and weaknesses, J Nephrol, 26, 55, 10.5301/jn.5000166
Eppenga, 2014, Risk of lactic acidosis or elevated lactate concentrations in metformin users with renal impairment: a population-based cohort study, Diabetes Care, 37, 2218, 10.2337/dc13-3023
Richy, 2014, Incidence of lactic acidosis in patients with type 2 diabetes with and without renal impairment treated with metformin: a retrospective cohort study, Diabetes Care, 37, 2291, 10.2337/dc14-0464
DeFronzo, 1995, Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group, N Engl J Med, 333, 541, 10.1056/NEJM199508313330902
Waters, 1978, Blood lactate and pyruvate levels in diabetic patients treated with biguanides with and without sulphonylureas, Diabetologia, 14, 95, 10.1007/BF01263446
Fery, 1997, Effects of metformin on the pathways of glucose utilization after oral glucose in non-insulin-dependent diabetes mellitus patients, Metabolism, 46, 227, 10.1016/S0026-0495(97)90307-3
Chan, 1999, Metformin-associated lactic acidosis: a rare or very rare clinical entity?, Diabet Med, 16, 273, 10.1046/j.1464-5491.1999.00006.x
Wang, 2003, Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin, Mol Pharmacol, 63, 844, 10.1124/mol.63.4.844
Graham, 2011, Clinical pharmacokinetics of metformin, Clin Pharmacokinet, 50, 81, 10.2165/11534750-000000000-00000
Kajbaf, 2015, Unexpectedly long half-life of metformin elimination in cases of metformin accumulation, Diabet Med
Ncomanzi, 2014, Metformin-associated lactic acidosis presenting as an ischemic gut in a patient who then survived a cardiac arrest: a case report, J Med Case Rep, 8, 159, 10.1186/1752-1947-8-159
Naunton, 2014, Pharmacist review prevents evolving metformin-associated lactic acidosis, J Clin Pharm Ther, 39, 567, 10.1111/jcpt.12187
Hussain, 2014, Acute renal failure and metformin-associated lactic acidosis following colonoscopy, Diabetes Res Clin Pract, 105, e6, 10.1016/j.diabres.2013.12.055
Kim, 2015, Metformin-associated lactic acidosis: predisposing factors and outcome, Endocrinol Metab, 30, 78, 10.3803/EnM.2015.30.1.78
Bridges, 2014, Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria, Biochem J, 462, 475, 10.1042/BJ20140620
Owen, 2000, Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain, Biochem J, 348, 607, 10.1042/bj3480607
Almirall, 2008, Metformin-associated lactic acidosis in type 2 diabetes mellitus: incidence and presentation in common clinical practice, Nephrol Dial Transplant, 23, 2436, 10.1093/ndt/gfn152
Lucis, 1983, The status of metformin in Canada, Can Med Assoc J, 128, 24
Frid, 2010, Novel assay of metformin levels in patients with type 2 diabetes and varying levels of renal function: clinical recommendations, Diabetes Care, 33, 1291, 10.2337/dc09-1284
Kalantar-Zadeh, 2013, Case records of the Massachusetts General Hospital. Case 23-2013. A 54-year-old woman with abdominal pain, vomiting, and confusion, N Engl J Med, 369, 374, 10.1056/NEJMcpc1208154
Lalau, 2001, Lactic acidosis in metformin therapy: searching for a link with metformin in reports of 'metformin-associated lactic acidosis', Diabetes Obes Metab, 3, 195, 10.1046/j.1463-1326.2001.00128.x
Devetzis, 2011, Metformin-related lactic acidosis in patients with acute kidney injury, Int Urol Nephrol, 43, 1243, 10.1007/s11255-010-9845-1
Silvestre, 2007, Metformin-induced lactic acidosis: a case series, J Med Case Rep, 1, 126, 10.1186/1752-1947-1-126
Bruijstens, 2008, Reality of severe metformin-induced lactic acidosis in the absence of chronic renal impairment, Neth J Med, 66, 185
Keller, 2011, Management of metformin-associated lactic acidosis by continuous renal replacement therapy, PLoS One, 6, e23200, 10.1371/journal.pone.0023200
Brassoe, 2005, Fulminant lactic acidosis in two patients with type 2 diabetes treated with metformin, Diabet Med, 22, 1451, 10.1111/j.1464-5491.2005.01650.x
Laforest, 2013, Monitoring of metformin-induced lactic acidosis in a diabetic patient with acute kidney failure and effect of hemodialysis, Int J Clin Pharmacol Ther, 51, 147, 10.5414/CP201728
Padwal, 2011, Effect of gastric bypass surgery on the absorption and bioavailability of metformin, Diabetes Care, 34, 1295, 10.2337/dc10-2140
Guelho, 2014, Relation between metformin treatment and the development of hyperlactacidemia at the emergency room, Acta Med Port, 27, 196, 10.20344/amp.4071
Pernicova, 2014, Metformin - mode of action and clinical implications for diabetes and cancer, Nat Rev Endocrinol, 10, 143, 10.1038/nrendo.2013.256
Blough, 2015, Metformin-induced lactic acidosis with emphasis on the anion gap, Proc (Bayl Univ Med Cent), 28, 31, 10.1080/08998280.2015.11929178
Margiani, 2014, Metformin-associated lactic acidosis and temporary ileostomy: a case report, J Med Case Rep, 8, 449, 10.1186/1752-1947-8-449
Stades, 2004, Metformin and lactic acidosis: cause or coincidence? A review of case reports, J Intern Med, 255, 179, 10.1046/j.1365-2796.2003.01271.x
Lalau, 1999, Lactic acidosis in metformin-treated patients. Prognostic value of arterial lactate levels and plasma metformin concentrations, Drug Saf, 20, 377, 10.2165/00002018-199920040-00006
Kajbaf, 2013, The prognostic value of blood pH and lactate and metformin concentrations in severe metformin-associated lactic acidosis, BMC Pharmacol Toxicol, 14, 22, 10.1186/2050-6511-14-22
Lalau, 2014, Interpreting the consequences of metformin accumulation in an emergency context: impact of the time frame on the blood metformin levels, Int J Endocrinol, 2014, 717198, 10.1155/2014/717198
Vecchio, 2011, Metformin-induced lactic acidosis: no one left behind, Crit Care, 15, 107, 10.1186/cc9404
Arroyo, 2010, The MALAdy of metformin poisoning: is CVVH the cure?, Am J Ther, 17, 96, 10.1097/MJT.0b013e318197eab6
Seidowsky, 2009, Metformin-associated lactic acidosis: a prognostic and therapeutic study, Crit Care Med, 37, 2191, 10.1097/CCM.0b013e3181a02490
Friesecke, 2010, Outcome of severe lactic acidosis associated with metformin accumulation, Crit Care, 14, R226, 10.1186/cc9376
Levey, 2006, Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate, Ann Intern Med, 145, 247, 10.7326/0003-4819-145-4-200608150-00004
Sambol, 1995, Kidney function and age are both predictors of pharmacokinetics of metformin, J Clin Pharmacol, 35, 1094, 10.1002/j.1552-4604.1995.tb04033.x
Misbin, 2004, The phantom of lactic acidosis due to metformin in patients with diabetes, Diabetes Care, 27, 1791, 10.2337/diacare.27.7.1791
Goergen, 2010, Systematic review of current guidelines, and their evidence base, on risk of lactic acidosis after administration of contrast medium for patients receiving metformin, Radiology, 254, 261, 10.1148/radiol.09090690
Calabrese, 2002, Evaluation of prescribing practices: risk of lactic acidosis with metformin therapy, Arch Intern Med, 162, 434, 10.1001/archinte.162.4.434
Horlen, 2002, Frequency of inappropriate metformin prescriptions, JAMA, 287, 2504, 10.1001/jama.287.19.2504-a
Emslie-Smith, 2001, Contraindications to metformin therapy in patients with type 2 diabetes—a population-based study of adherence to prescribing guidelines, Diabet Med, 18, 483, 10.1046/j.1464-5491.2001.00509.x
Huang, 2015, Adverse event notifications implicating metformin with lactic acidosis in Australia, J Diabetes Complicat, 10.1016/j.jdiacomp.2015.06.001
Sweileh, 2007, Contraindications to metformin therapy among patients with type 2 diabetes mellitus, Pharm World Sci, 29, 587, 10.1007/s11096-007-9095-1
2009, Type 2 diabetes: the management of type 2 diabetes
Rojas, 2013, Metformin: an old but still the best treatment for type 2 diabetes, Diabetol Metab Syndr, 5, 6, 10.1186/1758-5996-5-6
Ekström, 2012, Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register, BMJ Open, 2, e001076, 10.1136/bmjopen-2012-001076
Lipska, 2011, Use of metformin in the setting of mild-to-moderate renal insufficiency, Diabetes Care, 34, 1431, 10.2337/dc10-2361
2012, Cases of lactic acidosis in patients undergoing treatment with metformin for the treatment of type 2 diabetes
Hanatani, 2015, Impact of Japanese regulatory action on metformin-associated lactic acidosis in type II diabetes patients, Int J Clin Pharm, 37, 537, 10.1007/s11096-015-0097-0
Hung, 2015, Metformin use and mortality in patients with advanced chronic kidney disease: national, retrospective, observational, cohort study, Lancet Diabetes Endocrinol, 3, 605, 10.1016/S2213-8587(15)00123-0
Kalantar-Zadeh, 2015, Metformin in chronic kidney disease: more harm than help?, Lancet Diabetes Endocrinol, 3, 579, 10.1016/S2213-8587(15)00133-3
Edwards, 2015, Chronic kidney disease: metformin increases risk of mortality in patients with advanced chronic kidney disease, Nat Rev Nephrol, 11, 443, 10.1038/nrneph.2015.110
Adam, 2014, A justification for less restrictive guidelines on the use of metformin in stable chronic renal failure, Diabet Med, 31, 1032, 10.1111/dme.12515
Jones, 2015, Comment on 'A justification for less restrictive guidelines on the use of metformin in stable chronic renal failure', Diabet Med, 32, 287, 10.1111/dme.12626
Stang, 1999, Incidence of lactic acidosis in metformin users, Diabetes Care, 22, 925, 10.2337/diacare.22.6.925
Perrone, 2011, Occult metformin toxicity in three patients with profound lactic acidosis, J Emerg Med, 40, 271, 10.1016/j.jemermed.2007.11.055
Guo, 2006, Severe lactic acidosis treated with prolonged hemodialysis: recovery after massive overdoses of metformin, Semin Dial, 19, 80, 10.1111/j.1525-139X.2006.00123.x
Timbrell, 2012, Lactic acidosis secondary to metformin overdose: a case report, J Med Case Rep, 6, 230, 10.1186/1752-1947-6-230
Dell'Aglio, 2010, Metformin overdose with a resultant serum pH of 6.59: survival without sequalae, J Emerg Med, 39, e77, 10.1016/j.jemermed.2007.09.034
Yang, 2009, Successful treatment of severe lactic acidosis caused by a suicide attempt with a metformin overdose, Kaohsiung J Med Sci, 25, 93, 10.1016/S1607-551X(09)70047-6
Galea, 2007, Severe lactic acidosis and rhabdomyolysis following metformin and ramipril overdose, Br J Anaesth, 98, 213, 10.1093/bja/ael347
Panzer, 2004, Combination of intermittent haemodialysis and high-volume continuous haemofiltration for the treatment of severe metformin-induced lactic acidosis, Nephrol Dial Transplant, 19, 2157, 10.1093/ndt/gfh337
Chang, 2002, High anion gap metabolic acidosis in suicide: don't forget metformin intoxication—two patients' experiences, Ren Fail, 24, 671, 10.1081/JDI-120013973
Suchard, 2008, Fatal metformin overdose presenting with progressive hyperglycemia, West J Emerg Med, 9, 160
von Mach, 2004, Experiences of a poison center with metformin-associated lactic acidosis, Exp Clin Endocrinol Diabetes, 112, 187, 10.1055/s-2004-819164
Baro-Serra, 2012, The importance of early haemodiafiltration in the treatment of lactic acidosis associated with the administration of metformin, Nefrologia, 32, 664
Heaney, 1997, Bicarbonate haemodialysis as a treatment of metformin overdose, Nephrol Dial Transplant, 12, 1046, 10.1093/ndt/12.5.1046
Lam, 2012, Metformin-associated lactic acidosis following intentional overdose successfully treated with tris-hydroxymethyl aminomethand and renal replacement therapy. Case Reports in, Nephrology, 2012
Harvey, 2005, Severe lactic acidosis complicating metformin overdose successfully treated with high-volume venovenous hemofiltration and aggressive alkalinization, Pediatr Crit Care Med, 6, 598, 10.1097/01.PCC.0000162451.47034.4F
Cryer, 2005, Comparative outcomes study of metformin intervention versus conventional approach the COSMIC Approach Study, Diabetes Care, 28, 539, 10.2337/diacare.28.3.539
Salpeter, 2010, Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus, Cochrane Database Syst Rev, CD002967
Bodmer, 2008, Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia: a nested case–control analysis, Diabetes Care, 31, 2086, 10.2337/dc08-1171
Kruse, 2004, Review: metformin does not increase risk for lactic acidosis or increase lactate levels in type 2 diabetes, ACP J Club, 141, 7, 10.7326/ACPJC-2004-141-1-007
Fall, 2005, Lactic acidosis: from sour milk to septic shock, J Intensive Care Med, 20, 255, 10.1177/0885066605278644
Stacpoole, 1993, Lactic acidosis, Endocrinol Metab Clin North Am, 22, 221, 10.1016/S0889-8529(18)30163-4
Bartlett, 1984, The influence of renal function on lactate and glucose metabolism, Biochem J, 219, 73, 10.1042/bj2190073
Madiraju, 2014, Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase, Nature, 510, 542, 10.1038/nature13270
Hong, 2008, Population exposure-response modeling of metformin in patients with type 2 diabetes mellitus, J Clin Pharmacol, 48, 696, 10.1177/0091270008316884
Lalau, 1995, Role of metformin accumulation in metformin-associated lactic acidosis, Diabetes Care, 18, 779, 10.2337/diacare.18.6.779
Marchetti, 1987, Plasma biguanide levels are correlated with metabolic effects in diabetic patients, Clin Pharmacol Ther, 41, 450, 10.1038/clpt.1987.55
Scarpello, 2001, Review: optimal dosing strategies for maximising the clinical response to metformin in type 2 diabetes, Br J Diabetes Vasc Dis, 1, 28, 10.1177/14746514010010010501
Davis, 2001, The relationship between metformin therapy and the fasting plasma lactate in type 2 diabetes: the Fremantle Diabetes Study, Br J Clin Pharmacol, 52, 137, 10.1046/j.0306-5251.2001.01423.x
Boulé, 2011, Metformin and exercise in type 2 diabetes: examining treatment modality interactions, Diabetes Care, 34, 1469, 10.2337/dc10-2207
Cunha, 2008, Cardiovascular, metabolic and hormonal responses to the progressive exercise performed to exhaustion in patients with type 2 diabetes treated with metformin or glyburide, Diabetes Obes Metab, 10, 238, 10.1111/j.1463-1326.2006.00690.x
Stumvoll, 1995, Metabolic effects of metformin in non-insulin-dependent diabetes mellitus, N Engl J Med, 333, 550, 10.1056/NEJM199508313330903
Protti, 2010, Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication, Crit Care, 14, R22, 10.1186/cc8885
Brunmair, 2004, Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?, Diabetes, 53, 1052, 10.2337/diabetes.53.4.1052
Zmijewski, 2008, Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury, Am J Respir Crit Care Med, 178, 168, 10.1164/rccm.200710-1602OC
El-Mir, 2000, Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I, J Biol Chem, 275, 223, 10.1074/jbc.275.1.223
Al-Abri, 2013, Metformin overdose-induced hypoglycemia in the absence of other antidiabetic drugs, Clin Toxicol (Phila), 51, 444, 10.3109/15563650.2013.784774
Chen, 2015, metformin administration into the ileum is not associated with increased systemic lactate
Bakris, 2014, Effects of new metformin formulation in stage 3 and 4 CKD: a pilot study, J Am Soc Nephrol, 25, 549A
DeFronzo, 2013, Dissociation between metformin plasma exposure and its glucose-lowering effect: a novel gut-mediated mechanism of action, 1087-P