Melanoma epidemiology, biology and prognosis
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Chang, 1998, The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society, Cancer, 83, 1664, 10.1002/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO;2-G
Ferlay, 2010, Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008, Int J Cancer, 127, 2893, 10.1002/ijc.25516
Forsea, 2012, Melanoma incidence and mortality in Europe: new estimates, persistent disparities, Br J Dermatol, 167, 1124, 10.1111/j.1365-2133.2012.11125.x
Cockburn, 2008, Melanoma underreporting: why does it happen, how big is the problem, and how do we fix it?, J Am Acad Dermatol, 59, 1081, 10.1016/j.jaad.2008.08.007
Galvin, A. and Walsh, P. Cancer atlas of the United Kingdom and Ireland 1991–2000 – preliminary pages. Chapter 14 Melanoma of skin. Office of National Statistics; 05 July 2005. SMPS No. 68.
Coleman, 1993
Kohler, 2011, Annual report to the nation on the status of cancer, 1975–2007, featuring tumors of the brain and other nervous system, J Natl Cancer Inst, 103, 714, 10.1093/jnci/djr077
Cancer Statistics. http://info.cancerresearchuk.org/cancerstats/; 2011 [accessed 17.11.11].
Cancer Statistics. www.cancerresearchuk.org; 2011 [accessed 18.11.11].
Geller, 2006, Crafting a melanoma educational campaign to reach middle-aged and older men, J Cutan Med Surg, 10, 259, 10.2310/7750.2006.00066
Rees, 2003, Genetics of hair and skin color, Ann Rev Genet, 37, 67, 10.1146/annurev.genet.37.110801.143233
Bulliard, 1994, Latitude gradients in melanoma incidence and mortality in the non-Maori population of New Zealand, Cancer Cause Control, 5, 234, 10.1007/BF01830242
Pennello, 2000, Association of surface ultraviolet B radiation levels with melanoma and nonmelanoma skin cancer in United States blacks, Cancer Epidemiol Biomarkers Prev, 9, 291
Lea, 2007, Ambient UVB and melanoma risk in the United States: a case–control analysis, Ann Epidemiol, 17, 447, 10.1016/j.annepidem.2007.01.030
Gilchrest, 1999, The pathogenesis of melanoma induced by ultraviolet radiation, N Engl J Med, 340, 1341, 10.1056/NEJM199904293401707
Elwood, 1997, Melanoma and sun exposure: an overview of published studies, Int J Cancer, 73, 198, 10.1002/(SICI)1097-0215(19971009)73:2<198::AID-IJC6>3.0.CO;2-R
Kricker, 2007, Ambient UV, personal sun exposure and risk of multiple primary melanomas, Cancer Cause Control, 18, 295, 10.1007/s10552-006-0091-x
Kraemer, 1994, The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm, Arch Dermatol, 130, 1018, 10.1001/archderm.1994.01690080084012
Cooke, 1985, Migration and death from malignant melanoma, Int J Cancer, 36, 175, 10.1002/ijc.2910360208
Holman, 1984, Cutaneous malignant melanoma and indicators of total accumulated exposure to the sun: an analysis separating histogenetic types, J Natl Cancer Inst, 73, 75
Nelemans, 1993, Effect of intermittent exposure to sunlight on melanoma risk among indoor workers and sun-sensitive individuals, Environ Health Persp, 101, 252, 10.1289/ehp.93101252
White, 1994, Case–control study of malignant melanoma in Washington State. I. Constitutional factors and sun exposure, Am J Epidemiol, 139, 857, 10.1093/oxfordjournals.aje.a117092
Wang, 2001, Ultraviolet A and melanoma: a review, J Am Acad Dermatol, 44, 837, 10.1067/mjd.2001.114594
Stern, 2001, Study PFu. The risk of melanoma in association with long-term exposure to PUVA, J Am Acad Dermatol, 44, 755, 10.1067/mjd.2001.114576
2007, The association of use of sunbeds with cutaneous malignant melanoma and other skin cancers: a systematic review, Int J Cancer, 120, 1116, 10.1002/ijc.22453
Lazovich, 2010, Indoor tanning and risk of melanoma: a case–control study in a highly exposed population, Cancer Epidemiol Biomarkers Prev, 19, 1557, 10.1158/1055-9965.EPI-09-1249
Cust, 2011, Sunbed use during adolescence and early adulthood is associated with increased risk of early-onset melanoma, Int J Cancer, 128, 2425, 10.1002/ijc.25576
Veierod, 2010, Sun and solarium exposure and melanoma risk: effects of age, pigmentary characteristics, and nevi, Cancer Epidemiol Biomarkers Prev, 19, 111, 10.1158/1055-9965.EPI-09-0567
El Ghissassi, 2009, A review of human carcinogens – part D: radiation, Lancet Oncol, 10, 751, 10.1016/S1470-2045(09)70213-X
Merimsky, 1998, Cigarette smoking and skin cancer, Clin Dermatol, 16, 585, 10.1016/S0738-081X(98)00043-1
Penn, 1993, The effect of immunosuppression on pre-existing cancers, Transplantation, 55, 742, 10.1097/00007890-199304000-00011
Penn, 1996, Malignant melanoma in organ allograft recipients, Transplantation, 61, 274, 10.1097/00007890-199601270-00019
Marghoob, 1995, Basal cell and squamous cell carcinomas are important risk factors for cutaneous malignant melanoma. Screening implications, Cancer, 75, 707, 10.1002/1097-0142(19950115)75:2+<707::AID-CNCR2820751415>3.0.CO;2-W
Kahn, 1998, Increased cancer mortality following a history of nonmelanoma skin cancer, JAMA, 280, 910, 10.1001/jama.280.10.910
Whiteman, 2003, Melanocytic nevi, solar keratoses, and divergent pathways to cutaneous melanoma, J Natl Cancer Inst, 95, 806, 10.1093/jnci/95.11.806
Olsen, 2009, Nevus density and melanoma risk in women: a pooled analysis to test the divergent pathway hypothesis, Int J Cancer, 124, 937, 10.1002/ijc.24011
DiFronzo, 1999, Increased incidence of second primary melanoma in patients with a previous cutaneous melanoma, Ann Surg Oncol, 6, 705, 10.1007/s10434-999-0705-0
Ferrone, 2005, Clinicopathological features of and risk factors for multiple primary melanomas, JAMA, 294, 1647, 10.1001/jama.294.13.1647
Levi, 2005, High constant incidence rates of second cutaneous melanomas, Int J Cancer, 117, 877, 10.1002/ijc.21262
Fountain, 1992, Homozygous deletions within human chromosome band 9p21 in melanoma, Proc Natl Acad Sci U S A, 89, 10557, 10.1073/pnas.89.21.10557
Cannon-Albright, 1992, Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22, Science, 258, 1148, 10.1126/science.1439824
Kamb, 1994, A cell cycle regulator potentially involved in genesis of many tumor types, Science, 264, 436, 10.1126/science.8153634
Nobori, 1994, Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers, Nature, 368, 753, 10.1038/368753a0
Piepkorn, 2000, Melanoma genetics: an update with focus on the CDKN2A(p16)/ARF tumor suppressors, J Am Acad Dermatol, 42, 705, 10.1067/mjd.2000.104687
Goldstein, 2007, Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents, J Med Genet, 44, 99, 10.1136/jmg.2006.043802
Molven, 2005, A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation, Genes Chromosomes Cancer, 44, 10, 10.1002/gcc.20202
Fletcher, 2004, Lifetime risks of common cancers among retinoblastoma survivors, J Natl Cancer Inst, 96, 357, 10.1093/jnci/djh058
Eng, 1993, Mortality from second tumors among long-term survivors of retinoblastoma, J Natl Cancer Inst, 85, 1121, 10.1093/jnci/85.14.1121
Chin, 2006, Malignant melanoma: genetics and therapeutics in the genomic era, Genes Dev, 20, 2149, 10.1101/gad.1437206
Berwick, 2006, The prevalence of CDKN2A germ-line mutations and relative risk for cutaneous malignant melanoma: an international population-based study, Cancer Epidemiol Biomarkers Prev, 15, 1520, 10.1158/1055-9965.EPI-06-0270
Box, 2001, MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations, Am J Hum Genet, 69, 765, 10.1086/323412
Demenais, 2010, Association of MC1R variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study, J Natl Cancer Inst, 102, 1568, 10.1093/jnci/djq363
Goldstein, 1995, Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations, N Engl J Med, 333, 970, 10.1056/NEJM199510123331504
Vasen, 2000, Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden), Int J Cancer, 87, 809, 10.1002/1097-0215(20000915)87:6<809::AID-IJC8>3.0.CO;2-U
Whelan, 1995, Brief report: a familial syndrome of pancreatic cancer and melanoma with a mutation in the CDKN2 tumor-suppressor gene, N Engl J Med, 333, 975, 10.1056/NEJM199510123331505
Cancer risks in BRCA2 mutation carriers. The Breast Cancer Linkage Consortium. J Natl Cancer Inst 1999;91:1310–6.
Kadouri, 2009, Absence of founder BRCA1 and BRCA2 mutations in cutaneous malignant melanoma patients of Ashkenazi origin, Fam Cancer, 8, 29, 10.1007/s10689-008-9206-8
Bishop, 2009, Genome-wide association study identifies three loci associated with melanoma risk, Nat Genet, 41, 920, 10.1038/ng.411
Brown, 2008, Common sequence variants on 20q11.22 confer melanoma susceptibility, Nat Genet, 40, 838, 10.1038/ng.163
Chatzinasiou, 2011, Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma, J Natl Cancer Inst, 103, 1227, 10.1093/jnci/djr219
Weber, 2001, Active Ras induces heterodimerization of cRaf and BRaf, Cancer Res, 61, 3595
Keyse, 2008, Kinase phosphatases (MKPs) and cancer, Cancer Metastasis Rev, 27, 253, 10.1007/s10555-008-9123-1
Dougherty, 2005, Regulation of Raf-1 by direct feedback phosphorylation, Mol Cell, 17, 215, 10.1016/j.molcel.2004.11.055
Demunter, 2001, Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma, J Invest Dermatol, 117, 1483, 10.1046/j.0022-202x.2001.01601.x
Omholt, 2003, NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression, Clin Cancer Res, 9, 6483
Sharma, 2005, Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors, Cancer Res, 65, 2412, 10.1158/0008-5472.CAN-04-2423
Poynter, 2006, BRAF and NRAS mutations in melanoma and melanocytic nevi, Melanoma Res, 16, 267, 10.1097/01.cmr.0000222600.73179.f3
Balch, 2009, Final version of 2009 AJCC melanoma staging and classification, J Clin Oncol, 27, 6199, 10.1200/JCO.2009.23.4799
Green, 2012, Population-based 20-year survival among people diagnosed with thin melanomas in Queensland, Australia, J Clin Oncol, 30, 1462, 10.1200/JCO.2011.38.8561
Balch, 2001, Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system, J Clin Oncol, 19, 3622, 10.1200/JCO.2001.19.16.3622
Balch, 1980, The prognostic significance of ulceration of cutaneous melanoma, Cancer, 45, 3012, 10.1002/1097-0142(19800615)45:12<3012::AID-CNCR2820451223>3.0.CO;2-O
Schuchter, 1996, A prognostic model for predicting 10-year survival in patients with primary melanoma. The Pigmented Lesion Group, Ann Intern Med, 125, 369, 10.7326/0003-4819-125-5-199609010-00003
Soong, 1992, Predicting survival and recurrence in localized melanoma: a multivariate approach, World J Surg, 16, 191, 10.1007/BF02071520
Thompson, 2011, Prognostic significance of mitotic rate in localized primary cutaneous melanoma: an analysis of patients in the multi-institutional American Joint Committee on Cancer melanoma staging database, J Clin Oncol, 29, 2199, 10.1200/JCO.2010.31.5812
Nagore, 2005, Prognostic factors in localized invasive cutaneous melanoma: high value of mitotic rate, vascular invasion and microscopic satellitosis, Melanoma Res, 15, 169, 10.1097/00008390-200506000-00005
Kashani-Sabet, 2001, Vascular involvement in the prognosis of primary cutaneous melanoma, Arch Dermatol, 137, 1169, 10.1001/archderm.137.9.1169
Kashani-Sabet, 2002, Tumor vascularity in the prognostic assessment of primary cutaneous melanoma, J Clin Oncol, 20, 1826, 10.1200/JCO.2002.07.082
Xu, 2012, Lymphatic invasion is independently prognostic of metastasis in primary cutaneous melanoma, Clin Cancer Res, 18, 229, 10.1158/1078-0432.CCR-11-0490
Callender, 2011, Prognostic implications of anatomic location of primary cutaneous melanoma of 1mm or thicker, Am J Surg, 202, 659, 10.1016/j.amjsurg.2011.06.048
Garbe, 1995, Primary cutaneous melanoma. Identification of prognostic groups and estimation of individual prognosis for 5093 patients, Cancer, 75, 2484, 10.1002/1097-0142(19950515)75:10<2484::AID-CNCR2820751014>3.0.CO;2-U
Balch, 2010, Multivariate analysis of prognostic factors among 2,313 patients with stage III melanoma: comparison of nodal micrometastases versus macrometastases, J Clin Oncol, 28, 2452, 10.1200/JCO.2009.27.1627
Day, 1981, Malignant melanoma. Prognostic significance of “microscopic satellites” in the reticular dermis and subcutaneous fat, Ann Surg, 194, 108, 10.1097/00000658-198107000-00019
Austin, 1994, Age as a prognostic factor in the malignant melanoma population, Ann Surg Oncol, 1, 487, 10.1007/BF02303614
Masback, 2001, Prognostic factors in invasive cutaneous malignant melanoma: a population-based study and review, Melanoma Res, 11, 435, 10.1097/00008390-200110000-00001
Vossaert, 1992, Influence of gender on survival in patients with stage I malignant melanoma, J Am Acad Dermatol, 26, 429, 10.1016/0190-9622(92)70068-Q
Joosse, 2012, Superior outcome of women with stage I/II cutaneous melanoma: pooled analysis of four European Organisation for Research and Treatment of Cancer phase III trials, J Clin Oncol, 30, 2240, 10.1200/JCO.2011.38.0584
Shivers, 1998, Molecular staging of malignant melanoma: correlation with clinical outcome, JAMA, 280, 1410, 10.1001/jama.280.16.1410
Martenson, 2001, Serum S-100b protein as a prognostic marker in malignant cutaneous melanoma, J Clin Oncol, 19, 824, 10.1200/JCO.2001.19.3.824
Tarhini, 2009, Prognostic significance of serum S100B protein in high-risk surgically resected melanoma patients participating in Intergroup Trial ECOG 1694, J Clin Oncol, 27, 38, 10.1200/JCO.2008.17.1777
Long, 2011, Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma, J Clin Oncol, 29, 1239, 10.1200/JCO.2010.32.4327
Moreau, 2012, Prognostic value of BRAF(V(6)(0)(0)) mutations in melanoma patients after resection of metastatic lymph nodes, Ann Surg Oncol, 19, 4314, 10.1245/s10434-012-2457-5
Safaee Ardekani, 2012, The prognostic value of BRAF mutation in colorectal cancer and melanoma: a systematic review and meta-analysis, PLoS One, 7, e47054, 10.1371/journal.pone.0047054
Virgili, 2007, Incidence of uveal melanoma in Europe, Ophthalmology, 114, 2309, 10.1016/j.ophtha.2007.01.032
Kujala, 2003, Very long-term prognosis of patients with malignant uveal melanoma, Invest Ophth Vis Sci, 44, 4651, 10.1167/iovs.03-0538
Mortality in patients with small choroidal melanoma. COMS Report No. 4. The Collaborative Ocular Melanoma Study Group. Arch Ophthalmol 1997;115:886–93.
Singh, 2011, Uveal melanoma: trends in incidence, treatment, and survival, Ophthalmology, 118, 1881, 10.1016/j.ophtha.2011.01.040
Miller, 1981, Ocular malignant melanoma in South African blacks, Br J Ophthalmol, 65, 720, 10.1136/bjo.65.10.720
Seddon, 1990, Host factors, UV radiation, and risk of uveal melanoma. A case–control study, Arch Ophthalmol, 108, 1274, 10.1001/archopht.1990.01070110090031
Holly, 1990, Uveal melanoma in relation to ultraviolet light exposure and host factors, Cancer Res, 50, 5773
Rootman, 1984, Color as a risk factor in iris melanoma, Am J Ophthalmol, 98, 558, 10.1016/0002-9394(84)90240-X
Tucker, 1985, Sunlight exposure as risk factor for intraocular malignant melanoma, N Eng J Med, 313, 789, 10.1056/NEJM198509263131305
Vajdic, 2002, Sun exposure predicts risk of ocular melanoma in Australia, Int J Cancer, 101, 175, 10.1002/ijc.10579
Gallagher, 1985, Risk factors for ocular melanoma: Western Canada Melanoma Study, J Natl Cancer Inst, 74, 775
Pane, 2000, Ultraviolet light exposure as a risk factor for ocular melanoma in Queensland, Australia, Ophth Epidem, 7, 159, 10.1076/0928-6586(200009)731-VFT159
Brantley, 2000, Inactivation of retinoblastoma protein in uveal melanoma by phosphorylation of sites in the COOH-terminal region, Cancer Res, 60, 4320
Loercher, 2005, MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A, J Cell Biol, 168, 35, 10.1083/jcb.200410115
Brantley, 2000, Deregulation of the Rb and p53 pathways in uveal melanoma, Am J Pathol, 157, 1795, 10.1016/S0002-9440(10)64817-1
Abdel-Rahman, 2006, High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma, J Clin Oncol, 24, 288, 10.1200/JCO.2005.02.2418
Van Raamsdonk, 2009, Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi, Nature, 457, 599, 10.1038/nature07586
Onken, 2008, Oncogenic mutations in GNAQ occur early in uveal melanoma, Inv Ophth Vis Sci, 49, 5230, 10.1167/iovs.08-2145
Van Raamsdonk, 2010, Mutations in GNA11 in uveal melanoma, N Engl J Med, 363, 2191, 10.1056/NEJMoa1000584
Lee, 2003, Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis, J Biol Chem, 278, 10314, 10.1074/jbc.M212696200
Wu, 2012, Protein kinase C inhibitor AEB071 targets ocular melanoma harboring GNAQ mutations via effects on the PKC/Erk1/2 and PKC/NF-kappaB pathways, Mol Cancer Ther, 11, 1905, 10.1158/1535-7163.MCT-12-0121
Khalili, 2012, Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner, Clin Cancer Res, 18, 4345, 10.1158/1078-0432.CCR-11-3227
Harbour, 2010, Frequent mutation of BAP1 in metastasizing uveal melanomas, Science, 330, 1410, 10.1126/science.1194472
Jensen, 1998, BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression, Oncogene, 16, 1097, 10.1038/sj.onc.1201861
Machida, 2009, The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1, J Biol Chem, 284, 34179, 10.1074/jbc.M109.046755
Nishikawa, 2009, BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity, Cancer Res, 69, 111, 10.1158/0008-5472.CAN-08-3355
Carbone, 2012, BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs, J Transl Med, 10, 179, 10.1186/1479-5876-10-179
Njauw, 2012, Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous–ocular melanoma families, PLoS One, 7, e35295, 10.1371/journal.pone.0035295
Wiesner, 2011, Germline mutations in BAP1 predispose to melanocytic tumors, Nat Genet, 43, 1018, 10.1038/ng.910
Shweiki, 1992, Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis, Nature, 359, 843, 10.1038/359843a0
Boyd, 2002, Vascular endothelial growth factor is elevated in ocular fluids of eyes harbouring uveal melanoma: identification of a potential therapeutic window, Br J Oph, 86, 448, 10.1136/bjo.86.4.448
Missotten, 2006, Vascular endothelial growth factor a in eyes with uveal melanoma, Arch Ophth, 124, 1428, 10.1001/archopht.124.10.1428
el Filali, 2010, Regulation of VEGF-A in uveal melanoma, Inv Ophth Vis Sci, 51, 2329, 10.1167/iovs.09-4739
Sheidow, 2000, Expression of vascular endothelial growth factor in uveal melanoma and its correlation with metastasis, Br J Ophth, 84, 750, 10.1136/bjo.84.7.750
Horsman, 1993, Cytogenetic analysis of uveal melanoma. Consistent occurrence of monosomy 3 and trisomy 8q, Cancer, 71, 811, 10.1002/1097-0142(19930201)71:3<811::AID-CNCR2820710325>3.0.CO;2-F
Horsman, 1990, Monosomy 3 and isochromosome 8q in a uveal melanoma, Cancer Genet Cytogen, 45, 249, 10.1016/0165-4608(90)90090-W
Augsburger, 1990, Clinical prognostic factors in patients with posterior uveal malignant melanoma, Cancer, 66, 1596, 10.1002/1097-0142(19901001)66:7<1596::AID-CNCR2820660726>3.0.CO;2-6
Seddon, 1987, Death from uveal melanoma. Number of epithelioid cells and inverse SD of nucleolar area as prognostic factors, Arch Ophth, 105, 801, 10.1001/archopht.1987.01060060087039
Prescher, 1996, Prognostic implications of monosomy 3 in uveal melanoma, Lancet, 347, 1222, 10.1016/S0140-6736(96)90736-9
Shields, 2011, Prognosis of uveal melanoma in 500 cases using genetic testing of fine-needle aspiration biopsy specimens, Ophthalmology, 118, 396, 10.1016/j.ophtha.2010.05.023
Prescher, 1995, Cytogenetics of twelve cases of uveal melanoma and patterns of nonrandom anomalies and isochromosome formation, Cancer Genet Cytogen, 80, 40, 10.1016/0165-4608(94)00165-8
White, 1998, Correlation of cytogenetic abnormalities with the outcome of patients with uveal melanoma, Cancer, 83, 354, 10.1002/(SICI)1097-0142(19980715)83:2<354::AID-CNCR20>3.0.CO;2-R
Sisley, 2000, Association of specific chromosome alterations with tumour phenotype in posterior uveal melanoma, Br J Cancer, 82, 330, 10.1054/bjoc.1999.0923
Onken, 2004, Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death, Cancer Res, 64, 7205, 10.1158/0008-5472.CAN-04-1750
Lu, 2002, Melanocytes are potential immunocompetent cells: evidence from recognition of immunological characteristics of cultured human melanocytes, Pigment cell Res, 15, 454, 10.1034/j.1600-0749.2002.02065.x
Le Poole, 1993, A novel, antigen-presenting function of melanocytes and its possible relationship to hypopigmentary disorders, J Immunol, 151, 7284, 10.4049/jimmunol.151.12.7284
Mackintosh, 2001, The antimicrobial properties of melanocytes, melanosomes and melanin and the evolution of black skin, J Theor Biol, 211, 101, 10.1006/jtbi.2001.2331
Plonka, 2009, What are melanocytes really doing all day long...?, Exp Dermatol, 18, 799, 10.1111/j.1600-0625.2009.00912.x
McLaughlin, 2005, Incidence of noncutaneous melanomas in the US, Cancer, 103, 1000, 10.1002/cncr.20866
Mallone, 2012, Descriptive epidemiology of malignant mucosal and uveal melanomas and adnexal skin carcinomas in Europe, Eur J Cancer, 48, 1167, 10.1016/j.ejca.2011.10.004
Sutherland, 1994, Patient characteristics, methods of diagnosis, and treatment of mucous membrane melanoma in the United States of America, J Am Coll Surg, 179, 561
Pandey, 1998, Primary malignant melanoma of the mucous membranes, Eur J Surg Oncol, 24, 303, 10.1016/S0748-7983(98)80011-5
Pandey, 2002, Primary malignant mucosal melanoma of the head and neck region: pooled analysis of 60 published cases from India and review of literature, Eur J Cancer Prev, 11, 3, 10.1097/00008469-200202000-00002
Hicks, 2000, Oral mucosal melanoma: epidemiology and pathobiology, Oral Oncol, 36, 152, 10.1016/S1368-8375(99)00085-8
Dahlgren, 2005, Human papilloma virus (HPV) is rarely detected in malignant melanomas of sun sheltered mucosal membranes, Acta Oncol, 44, 694, 10.1080/02841860500247461
Lundberg, 2006, Human herpes virus DNA is rarely detected in non-UV light-associated primary malignant melanomas of mucous membranes, Anticancer Res, 26, 3627
Cote, 2009, Primary melanomas of the esophagus and anorectum: epidemiologic comparison with melanoma of the skin, Melanoma Res, 19, 58, 10.1097/CMR.0b013e32831ef262
Burgi, 2005, Incidence and risk factors for the occurrence of non-AIDS-defining cancers among human immunodeficiency virus-infected individuals, Cancer, 104, 1505, 10.1002/cncr.21334
Holmstrom, 1991, Malignant melanomas of the nasal cavity after occupational exposure to formaldehyde, Br J Ind Med, 48, 9
Axell, 1982, Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits, Scand J Dent Res, 90, 434
Manolidis, 1997, Malignant mucosal melanoma of the head and neck: review of the literature and report of 14 patients, Cancer, 80, 1373, 10.1002/(SICI)1097-0142(19971015)80:8<1373::AID-CNCR3>3.0.CO;2-G
Takagi, 1974, Primary malignant melanoma of the oral cavity in Japan. With special reference to mucosal melanosis, Cancer, 34, 358, 10.1002/1097-0142(197408)34:2<358::AID-CNCR2820340221>3.0.CO;2-D
Maldonado, 2003, Determinants of BRAF mutations in primary melanomas, J Natl Cancer Inst, 95, 1878, 10.1093/jnci/djg123
Curtin, 2005, Distinct sets of genetic alterations in melanoma, N Engl J Med, 353, 2135, 10.1056/NEJMoa050092
Grabbe, 1994, Stem cell factor, a novel cutaneous growth factor for mast cells and melanocytes, Arch Derm Res, 287, 78, 10.1007/BF00370723
Lev, 1992, Dimerization and activation of the kit receptor by monovalent and bivalent binding of the stem cell factor, J Biol Chem, 267, 15970, 10.1016/S0021-9258(19)49629-4
Giebel, 1991, Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism, Proc Natl Acad Sci U S A, 88, 8696, 10.1073/pnas.88.19.8696
Nishikawa, 1991, In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: two distinct waves of c-kit-dependency during melanocyte development, EMBO J, 10, 2111, 10.1002/j.1460-2075.1991.tb07744.x
Wehrle-Haller, 1995, Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway, Development, 121, 731, 10.1242/dev.121.3.731
Alexeev, 2006, Distinctive role of the cKit receptor tyrosine kinase signaling in mammalian melanocytes, J Invest Dermatol, 126, 1102, 10.1038/sj.jid.5700125
Natali, 1992, Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor, Int J Cancer, 52, 197, 10.1002/ijc.2910520207
Montone, 1997, Proto-oncogene c-kit expression in malignant melanoma: protein loss with tumor progression, Mod Pathol, 10, 939
Bastian, 1998, Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization, Cancer Res, 58, 2170
Bastian, 2000, Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin, Cancer Res, 60, 1968
van Dijk, 2003, Distinct chromosomal aberrations in sinonasal mucosal melanoma as detected by comparative genomic hybridization, Genes Chromosomes Canc, 36, 151, 10.1002/gcc.10156
Curtin, 2006, Somatic activation of KIT in distinct subtypes of melanoma, J Clin Oncol, 24, 4340, 10.1200/JCO.2006.06.2984
Beadling, 2008, KIT gene mutations and copy number in melanoma subtypes, Clin Cancer Res, 14, 6821, 10.1158/1078-0432.CCR-08-0575
Rivera, 2008, C-kit protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma, Virchows Arch, 452, 27, 10.1007/s00428-007-0524-2
Monsel, 2010, C-Kit mutants require hypoxia-inducible factor 1alpha to transform melanocytes, Oncogene, 29, 227, 10.1038/onc.2009.320