Lysozyme from rainbow trout, Salmo gairdneri Richardson, as an antibacterial agent against fish pathogens

Journal of Fish Diseases - Tập 12 Số 2 - Trang 95-104 - 1989
Bjørn Grinde1
1Department of Animal Husbandry and Genetics, Norwegian College of Veterinary Medicine and Department of Biotechnical Disease Control, National Veterinary Institute, Oslo, Norway

Tóm tắt

Abstract. The antibacterial effect of two lysozyme variants purified from rainbow trout, Salmo gairdneri Richardson, kidney was investigated as part of a project directed towards increasing the disease resistance of fish by the transgenic technique. Seven bacterial strains from five Gram‐negative species, of which one was considered non‐pathogenic, were examined. One of the rainbow trout lysozymes was surprisingly potent, having substantial antibacterial activity on all strains tested. Hen egg‐white lysozyme was bactericidal only against the one species considered non‐pathogenic. The data suggest that lysozyme does play a role in the disease defence of rainbow trout and that the gene for the most active lysozyme may be suitable for testing the transgenic strategy.

Từ khóa


Tài liệu tham khảo

10.1111/j.1365-2672.1985.tb01490.x

Carroll S. F., 1979, Role of rabbit lysozyme in in vitro serum and plasma serum bactericidal reactions against Bacillus subtilis, Infection and Immunity, 25, 810, 10.1128/iai.25.3.810-819.1979

10.1099/00207713-36-4-518

10.1007/BF00389289

10.1093/infdis/140.4.581

10.1007/BF01935119

10.1111/j.1432-1033.1988.tb13994.x

10.1016/0044-8486(88)90243-8

10.3147/jsfp.20.125

Iacono V. J., 1980, Selective antibacterial properties of lysozyme for oral microorganisms, Infection and Immunity, 29, 623, 10.1128/iai.29.2.623-632.1980

10.1111/j.1095-8649.1980.tb03685.x

10.1007/BF00285225

10.1016/0044-8486(86)90306-6

10.1111/j.1095-8649.1976.tb04681.x

10.1016/0045-6039(86)90100-4

10.3181/00379727-119-30188

10.1093/infdis/96.1.75

10.1016/0003-9969(83)90045-6

10.1016/0005-2736(76)90471-5

10.1111/j.1439-0426.1985.tb00408.x

Thông tin
Thông tin xuất bản

Journal of Fish Diseases

Tập 12 Số 2

95-104

Thông tin tác giả