Long-Term Persistence of Immunoglobulin A (IgA) and IgM Antibodies against Human Cytomegalovirus in Solid-Organ Transplant Recipients

American Society for Microbiology - Tập 6 Số 4 - Trang 621-623 - 1999
Bodo R. Eing1, H. Baumeister1, Joachim E. Kuehn1, Guenter May1
1<!--label omitted: 1-->Institute of Medical Microbiology, Clinical Virology, University of Muenster, Muenster, Germany

Tóm tắt

ABSTRACT

The retrospective analysis of 494 solid-organ transplant recipients revealed that during the follow-up period (mean duration, 3.2 years) 184 (88%) of 209 anti-human cytomegalovirus (HCMV) immunoglobulin A (IgA)-positive patients remained IgA positive, as did 128 (74.85%) of 171 anti-HCMV IgM-positive patients. We conclude that anti-HCMV IgA and IgM testing for management of clinically relevant HCMV infections in solid-organ transplant recipients is dispensable.

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Tài liệu tham khảo

10.1111/j.1432-2277.1993.tb00647.x

10.1002/(SICI)1096-9071(199603)48:3<289::AID-JMV13>3.0.CO;2-8

10.1002/jmv.1890440416

10.1128/JCM.36.11.3337-3341.1998

May G. Serological diagnosis of reactivated varicella-zoster virus infections by immunoglobulin A antibody detection. Klin. Lab. 42 1996 761 764

10.1097/00007890-199806150-00012

10.1128/jcm.26.4.654-661.1988

10.1007/BF01708555

10.1086/515383

10.1093/infdis/149.2.277

10.1159/000149236

10.1099/0022-1317-74-12-2699

10.1086/314468

10.1128/JCM.36.9.2681-2685.1998

10.1128/jcm.26.12.2531-2535.1988

10.1002/jmv.1890250208

10.1007/BF01710536