Local elevation of CCL22: A new trend in immunotherapy (skin model)

Hyduk, 2007, Phospholipase C, calcium,and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants, Blood, 109, 176, 10.1182/blood-2006-01-029199 Schaniel, 1998, Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells, J Exp Med, 188, 451, 10.1084/jem.188.3.451 Chang, 1997, Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes, J Biol Chem, 272, 25229, 10.1074/jbc.272.40.25229 Ross, 1999, Mouse langerhans cells differentially express an activated T cell-attracting CC chemokine, J Invest Dermatol, 113, 991, 10.1046/j.1523-1747.1999.00803.x Zlotnik, 2006, The chemokine and chemokine receptor superfamilies and their molecular evolution, Genome Biol, 7, 243, 10.1186/gb-2006-7-12-243 Imai, 1999, Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine, Int Immunol, 11, 81, 10.1093/intimm/11.1.81 Sebastiani, 2001, Chemokine receptor expression and function in CD4+ T lymphocytes with regulatory activity, J Immunol, 166, 996, 10.4049/jimmunol.166.2.996 Andrew, 1998, STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13, J Immunol, 161, 5027, 10.4049/jimmunol.161.9.5027 Ghadially, 2005, Differential regulation of CCL22 gene expression in murine dendritic cells and B cells, J Immunol, 174, 5620, 10.4049/jimmunol.174.9.5620 Yoshino, 2003, Distinct antigen trafficking from skin in the steady and active states, Int Immunol, 15, 773, 10.1093/intimm/dxg075 Clark, 2010, Skin-resident T cells: the ups and downs of on site immunity, J Invest Dermatol, 130, 362, 10.1038/jid.2009.247 Steinman, 2003, Tolerogenic dendritic cells, Annu Rev Immunol, 21, 685, 10.1146/annurev.immunol.21.120601.141040 Seneschal, 2012, Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells, Immunity, 36, 873, 10.1016/j.immuni.2012.03.018 Clark, 2006, The vast majority of CLA+ T cells are resident in normal skin, J Immunol, 176, 4431, 10.4049/jimmunol.176.7.4431 Clark, 2008, Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells, J Exp Med, 205, 2221, 10.1084/jem.20071190 Bala, 2006, Induction and maintenance of self tolerance: the role of CD4+CD25+ regulatory T cells, Arch Immunol Ther Exp Warsz, 54, 307, 10.1007/s00005-006-0035-x Steitz, 2004, Initiation and regulation of CD8+T cells recognizing melanocytic antigens in the epidermis: implications for the pathophysiology of vitiligo, Eur J Cell Biol, 83, 797, 10.1078/0171-9335-00423 Klarquist, 2010, Reduced skin homing by functional Treg in vitiligo, Pigment Cell Melanoma Res, 23, 276, 10.1111/j.1755-148X.2010.00688.x Yadav, 2012, Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo, J Exp Med, 209, 1713, 10.1084/jem.20120822 Vulcano, 2001, Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo, Eur J Immunol, 31, 812, 10.1002/1521-4141(200103)31:3<812::AID-IMMU812>3.0.CO;2-L Bosma, 2008, Dexamethasone transforms lipopolysaccharide-stimulated human blood myeloid dendritic cells into myeloid dendritic cells that prime interleukin-10 production in T cells, Immunology, 125, 91, 10.1111/j.1365-2567.2008.02824.x Stary, 2011, Glucocorticosteroids modify Langerhans cells to produce TGF-beta and expand regulatory T cells, J Immunol, 186, 103, 10.4049/jimmunol.1002485 Berman, 2013, Pathobiology of actinic keratosis: ultraviolet-dependent keratinocyte proliferation, J Am Acad Dermatol, 68, S10, 10.1016/j.jaad.2012.09.053 Taguchi, 2013, The role of epidermal Langerhans cells in NB-UVB-induced immunosuppression, Kobe J Med Sci, 59, E1 van der Aar, 2011, Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells, J Allergy Clin Immunol, 127, 1532, 10.1016/j.jaci.2011.01.068 Peelen, 2011, Effects of vitamin D on the peripheral adaptive immune system: a review, Autoimmun Rev, 10, 733, 10.1016/j.autrev.2011.05.002 Fu, 2005, Salmonella enterica Serovar Typhimurium infection of dendritic cells leads to functionally increased expression of the macrophage-derived chemokine, Infect Immun, 73, 1714, 10.1128/IAI.73.3.1714-1722.2005 Wang, 2011, Th17 cells and activated dendritic cells are increased in vitiligo lesions, PLoS One, 6, e18907, 10.1371/journal.pone.0018907 Liu, 2012, Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: Vbeta13 as a therapeutic target and biomarker, Diabetes, 61, 1160, 10.2337/db11-0867 Han, 1996, A new type of CD4+ suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice, J Autoimmun, 9, 331, 10.1006/jaut.1996.0045 Montane, 2011, Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets, J Clin Invest, 121, 3024, 10.1172/JCI43048 Jhunjhunwala, 2012, Bioinspired controlled release of CCL22 recruits regulatory T cells in vivo, Adv Mater, 24, 4735, 10.1002/adma.201202513