Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo

International Journal of Pharmaceutics - Tập 547 - Trang 537-544 - 2018
Qian-Yu Zhang1, Pui Yan Ho1, Mei-Juan Tu1, Joseph L. Jilek1, Qiu-Xia Chen1,2, Su Zeng2, Ai-Ming Yu1
1Department of Biochemistry & Molecular Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA
2College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China

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